Patents by Inventor Graham John Boulnois

Graham John Boulnois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pneumolysin mutants and pneumococcal vaccines made therefrom
    Patent number: 6716432
    Abstract: Mutants of pneumolysin that are non-toxic by reason of amino acid substitutions have been constructed. These mutants elicit an immune response in animals that is reactive to wild-type pneumolysin. The invention also encompasses vaccines for humans based on these mutants, including vaccines comprising conjugates with pneumococcal capsular polysaccharides.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: April 6, 2004
    Inventors: James Cleland Paton, David John Hansman, Graham John Boulnois, Peter William Andrew, Timothy John Mitchell, John Arthur Walker