Patents by Inventor Graham John Hamilton Melrose

Graham John Hamilton Melrose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220401469
    Abstract: A process for preparation of a biologically active polymer comprising an acrolein derived segment and a polyalkylene glycol oligomer, the process comprising reacting polyalkylene glycol with acrolein in aqueous solution to form a copolymer of molecular weight no more than 1000 Daltons at a temperature of no more than 15° C.
    Type: Application
    Filed: July 22, 2022
    Publication date: December 22, 2022
    Applicant: RECCE PHARMACEUTICALS LTD
    Inventors: Graham John Hamilton MELROSE, Michele Keryn DILIZIA, Thomas Gabriel, Wells JARRETT, Arthur KOLLARAS, Justin Mark WARD
  • Publication number: 20210275573
    Abstract: A method of treatment of viral infection in a subject comprising administering to the subject a copolymer comprising an acrolein derived segment or a polyacrolein oligomer segment and a polyalkylene glycol oligomer segment, the copolymer having a molecular weight of no more than 1500 Daltons.
    Type: Application
    Filed: May 21, 2021
    Publication date: September 9, 2021
    Inventors: Graham John Hamilton MELROSE, Michele Keryn DILIZIA
  • Patent number: 11045491
    Abstract: A method of treatment of viral infection in a subject comprising administering to the subject a copolymer comprising an acrolein derived segment or a polyacrolein oligomer segment and a polyalkylene glycol oligomer segment, the copolymer having a molecular weight of no more than 1500 Daltons.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: June 29, 2021
    Assignee: RECCE PHARMACEUTICALS LTD
    Inventors: Graham John Hamilton Melrose, Michele Keryn Dilizia
  • Patent number: 10226482
    Abstract: A method of treatment of infection in a subject comprising administering to the subject a copolymer comprising an acrolein derived segment or a polyacrolein oligomer segment and a polyalkylene glycol oligomer segment, the copolymer having a molecular weight of no more than 1500 Daltons.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: March 12, 2019
    Assignee: RECCE PHARMACEUTICALS LIMITED
    Inventors: Graham John Hamilton Melrose, Michele Keryn Dilizia
  • Publication number: 20180338994
    Abstract: A method of treatment of viral infection in a subject comprising administering to the subject a copolymer comprising an acrolein derived segment or a polyacrolein oligomer segment and a polyalkylene glycol oligomer segment, the copolymer having a molecular weight of no more than 1500 Daltons.
    Type: Application
    Filed: February 17, 2017
    Publication date: November 29, 2018
    Inventors: Graham John Hamilton MELROSE, Michele Keryn DILIZIA
  • Publication number: 20170281669
    Abstract: A method of treatment of infection in a subject comprising administering to the subject a copolymer comprising an acrolein derived segment or a polyacrolein oligomer segment and a polyalkylene glycol oligomer segment, the copolymer having a molecular weight of no more than 1500 Daltons.
    Type: Application
    Filed: November 17, 2015
    Publication date: October 5, 2017
    Inventors: Graham John Hamilton MELROSE, Michele Keryn DILIZIA
  • Patent number: 7629002
    Abstract: A polymeric antimicrobial comprising a derivative of poly(2-propenal, 2-propenoic acid) formed by reaction between a poly(2-propenal, 2-propenoic acid) and an alcohol or phenol to form protected carbonyl groups. The invention also relates to antiseptic compositions and compositions for treating gastrointestinal disease containing the polymeric antimicrobial.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: December 8, 2009
    Assignee: Chemeq Ltd.
    Inventors: Graham John Hamilton Melrose, Andrew James Huxham
  • Publication number: 20090011023
    Abstract: The present invention relates to the treatment of gastrointestinal and/or cancer, and a method of weight gain, via the ingestion of polymeric compositions in humans, animals or birds in need of said treatment. The invention provides methods for the treatment of cancer, the treatment and/or prevention of gastrointestinal disease and/or infection and/or diarrhea, and a method for increasing weight gain in humans, animals or birds comprising administering to said humans, animals or birds an effective amount of a pharmaceutical or veterinary composition, or feed additive, comprising an effective amount of a polymer and/or copolymer, having the repeating polymeric unit (I), wherein R is H or alkyl, usually C1 to C4, or this unit in hydrated, hemiacetal or acetal form, together with a pharmaceutically or veterinarally acceptable carrier, diluent, adjuvant, excipient and/or controlled release system.
    Type: Application
    Filed: September 15, 2008
    Publication date: January 8, 2009
    Inventor: Graham John Hamilton MELROSE
  • Patent number: 7438899
    Abstract: The present invention relates to the treatment of gastrointestinal disease and/or cancer, and a method of weight gain, via the ingestion of polymeric compositions in humans, animals or birds in need of said treatment. The invention provides methods for the treatment of cancer, the treatment and/or prevention of gastrointestinal disease and/or infection and/or diarrhoea, and a method for increasing weight gain in humans, animals or birds comprising administering to said humans, animals or birds an effective amount of a pharmaceutical or veterinary composition, or feed additive, comprising an effective amount of a polymer and/or copolymer, having the repeating polymeric unit (I), wherein R is H or alkyl, usually C1 to C4, or this unit in hydrated, hemiacetal or acetal form, together with a pharmaceutically or veterinarally acceptable carrier, diluent, adjuvant, excipient and/or controlled release system.
    Type: Grant
    Filed: March 5, 2004
    Date of Patent: October 21, 2008
    Assignee: Chemeq Ltd.
    Inventor: Graham John Hamilton Melrose
  • Patent number: 6803356
    Abstract: A method for the preparation of polymers derived from acrolein and including poly(2-propenal, 2-propenoic acid), characterised in that the polymers are exposed to the presence of water, whereby such polymers exhibit increased antimicrobial activity. The polymers may be heated in the range of 40 to 150° C. Further, the polymers may be prepared in the presence of polyethylene glycols, polyols and/or alkanols.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: October 12, 2004
    Assignee: Chemeq Ltd.
    Inventors: Graham John Hamilton Melrose, Gerry Daly, Andrew James Huxham
  • Publication number: 20040170599
    Abstract: The present invention relates to the treatment of gastrointestinal disease and/or cancer, and a method of weight gain, via the ingestion of polymeric compositions in humans, animals or birds in need of said treatment.
    Type: Application
    Filed: March 5, 2004
    Publication date: September 2, 2004
    Inventor: Graham John Hamilton Melrose
  • Patent number: 6723336
    Abstract: The present invention relates to the treatment of gastrointestinal disease and/or cancer, and a method of weight gain, via the ingestion of polymeric compositions in humans, animals or birds in need of said treatment. The invention provides methods for the treatment of cancer, the treatment and/or prevention of gastrointestinal disease and/or infection and/or diarrhea and a method for increasing weight gain in humans, animals or birds comprising administering to said humans, animals or birds an effective amount of a pharmaceutical or veterinary composition or feed additive, comprising an effective amount of a polymer and/or copolymer, having the repeating polymeric unit (I) wherein R is H or alkyl, usually C1 to C4, or this unit in hydrated, hemiacetal or acetal form, together with a pharmaceutically or veterinarally acceptable carrier, diluent, adjuvant, excipient and/or controlled release system.
    Type: Grant
    Filed: November 24, 1997
    Date of Patent: April 20, 2004
    Assignee: Chemeq Ltd.
    Inventor: Graham John Hamilton Melrose
  • Publication number: 20040013636
    Abstract: An emulsion composition for the topical application comprising: (a) A polymeric oily phase; (b) A polymeric emulsifier; (c) An aqueous phase; (d) A polymeric antimicrobial and optionally one or more components selected from polymeric film formers, inorganic and polymeric stabilizers, other inorganic or polymeric excipients and mixtures thereof.
    Type: Application
    Filed: July 28, 2003
    Publication date: January 22, 2004
    Inventors: John Alexander Staton, Graham John Hamilton Melrose
  • Publication number: 20030195131
    Abstract: A polymeric antimicrobial comprising a derivative of poly(2-propenal, 2-propenoic acid) formed by reaction between a poly(2-propenal, 2-propenoic acid) and an alcohol or phenol to form protected carbonyl groups. The invention also relates to antiseptic compositions and compositions for treating gastrointestinal disease containing the polymeric antimicrobial.
    Type: Application
    Filed: January 18, 2002
    Publication date: October 16, 2003
    Inventors: Graham John Hamilton Melrose, Gerry Daly, Andrew James Huxham, Damon Matthew Goadby Tilbrook