Patents by Inventor Graham Kyne

Graham Kyne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES
    Publication number: 20240025891
    Abstract: Provided herein are Heterocyclic Compounds of formula (I), formula (II), formula (III), formula (IlIa), formula (Mb), formula (IIIc), formula (Hid), formula (IV), formula (IVa), formula (IVb), and formula (IVc), and pharmaceutically acceptable salts, tautomers, isotopologues, and stereoisomers thereof, compositions comprising an effective amount of a Heterocyclic Compound of formula (I), formula (II), formula (III), formula (IlIa), formula (Mb), formula (IIIc), formula (Hid), formula (IV), formula (IVa), formula (IVb), and formula (IVc), and methods for treating or preventing animal and human filarial worm infections and diseases.
    Type: Application
    Filed: October 22, 2021
    Publication date: January 25, 2024
    Inventors: Natalie Hawryluk, Stacie Canan, Kevin R. Condroski, Matthew Bedore, Graham Kyne, Sanjay Menon
  • HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES
    Publication number: 20230146944
    Abstract: Provided herein are Heterocyclic compounds of formula I: and pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof, wherein W, X, Y, R1, R2, and RN are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound, and methods for treating or preventing animal and human filarial worm infections and diseases.
    Type: Application
    Filed: October 4, 2022
    Publication date: May 11, 2023
    Inventors: Natalie Hawryluk, Stacie S. Canan, Kevin R. Condroski, Graham Kyne, Matthew Bedore, Sanjay Menon
  • Heterocyclic compounds and their use for treatment of helminthic infections and diseases
    Patent number: 11505548
    Abstract: Provided herein are Heterocyclic compounds of formula I: and pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof, wherein W, X, Y, R1, R2, and RN are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound, and methods for treating or preventing animal and human filarial worm infections and diseases.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 22, 2022
    Assignees: CELGENE CORPORATION, ZOETIS LLC
    Inventors: Natalie Hawryluk, Stacie S. Canan, Kevin R. Condroski, Graham Kyne, Matthew Bedore, Sanjay Menon
  • HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES
    Publication number: 20200339559
    Abstract: Provided herein are Heterocyclic compounds of formula I: and pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof, wherein W, X, Y, R1, R2, and RN are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound, and methods for treating or preventing animal and human filarial worm infections and diseases.
    Type: Application
    Filed: April 24, 2020
    Publication date: October 29, 2020
    Inventors: Natalie Hawryluk, Stacie S. Canan, Kevin R. Condroski, Graham Kyne, Matthew Bedore, Sanjay Menon
  • COMBINATION
    Publication number: 20070149464
    Abstract: Compounds of formula (I) are used in combination with a second antiparasitic agent for the treatment of parasitic infestations in a host animal.
    Type: Application
    Filed: December 14, 2006
    Publication date: June 28, 2007
    Applicant: PFIZER INC.
    Inventors: Denis Billen, Jessica Boyle, Douglas Critcher, David Gethin, Kim Hall, Graham Kyne
  • SUBSTITUTED ARYLPYRAZOLES
    Publication number: 20070149550
    Abstract: This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
    Type: Application
    Filed: December 14, 2006
    Publication date: June 28, 2007
    Applicant: PFIZER INC.
    Inventors: Denis Billen, Jessica Boyle, Douglas Critcher, David Gethin, Kim Hall, Graham Kyne
  • Substituted arylpyrazoles
    Publication number: 20060287365
    Abstract: This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
    Type: Application
    Filed: June 14, 2006
    Publication date: December 21, 2006
    Inventors: Denis Billen, Jessica Boyle, Douglas Critcher, David Gethin, Kim Hall, Graham Kyne