Patents by Inventor Graham Michael Wynne

Graham Michael Wynne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090186923
    Abstract: Compounds of general formula (I) wherein W is chloro or fluoro; R1 is phenyl optionally substituted with one or more substituents selected from halo, —CN, —C1-C6 alkyl, —SOR3, —SO2R3, —SO2N(R2)2, —N(R2)2, —NR2C(O)R3, —CO2R2, —CONR2R3, —NO2, —OR2, —SR2, —O(CH2)pOR2, and —O(CH2)p—O—(CH2)qOR2 wherein each R2 is independently hydrogen, —C1-C6 alkyl, —C3-C8 cycloalkyl, aryl or heteroaryl; each R3 is independently, —C1-C6 alkyl, —C3-C8 cycloalkyl, aryl or heteroaryl; p and q are each independently an integer from 1 to 3; and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.
    Type: Application
    Filed: January 21, 2009
    Publication date: July 23, 2009
    Inventors: Richard Edward Armer, Eric Roy Pettipher, Mark Whittaker, Graham Michael Wynne, Julia Vile, Frank Schroer
  • Patent number: 7521448
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of cancer.
    Type: Grant
    Filed: August 16, 2004
    Date of Patent: April 21, 2009
    Assignee: OSI Pharmaceuticals, Inc.
    Inventors: Joshua Bolger, Arlindo L. Castelhano, Andrew Phillip Crew, Han-Qing Dong, Ayako Honda, Radoslaw Laufer, An-Hu Li, Kristen Mulvihill, Li Qiu, Colin Peter Sambrook Smith, Yingchaun Sun, Graham Michael Wynne, Tao Zhang
  • Publication number: 20090075938
    Abstract: There are disclosed compound of Formula (1): A1, A2, A3 and A4 which may be the same or different, represent N or CR1, X is a divalent group selected from O, S(O)n, C?W, NR4, NC(?O)R5 and CR6R7, W is O, S, NR20, Y is N or CR8, one of R4, R5, R6, R8, R9 and NR20 represents -L-R3, in which L is a single bond or a linker group, additionally, R1, R3-R9, which may be the same or different, independently represent hydrogen or a substituent and R20 represents hydrogen, hydroxyl, alkyl optionally substituted by aryl, alkoxy optionally substituted by aryl, aryl, CN, optionally substituted alkoxy, optionally substituted aryloxy, optionally substitute alkanoyl, optionally substituted aroyl, NO2, NR30R31, in which R30 and R31, which may be the same or different, represent hydrogen, optionally substituted alkyl or optionally substituted aryl; additionally, one of R30 and R31 may represent optionally substituted alkanoyl or optionally substituted aroyl, n represents an integer from 0 to 2, in addition, when an adjacent pai
    Type: Application
    Filed: February 9, 2007
    Publication date: March 19, 2009
    Inventors: Graham Michael Wynne, Stephen Paul Wren, Peter David Johnson, Paul Damien Price, Olivier De Moor, Gary Nugent, Richard Storer, Richard Joseph Pye, Colin Richard Dorgan
  • Patent number: 6949563
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, wherein R1 is R2 is and R3 is C0-4alkyl, are useful in the treatment of cancer.
    Type: Grant
    Filed: January 6, 2004
    Date of Patent: September 27, 2005
    Inventors: Graham Michael Wynne, Kevin Doyle, Saleh Ahmed, An-Hu Li, John Fraser Keily, Chrystelle Marie Rasamison, Neil Anthony Pegg, Imaad Saba, Claire Thomas, Don Smyth, Shazia Sadiq, Gary Newton, Graham Dawson, Andrew Phillip Crew, Arlindo Lucas Castelhano
  • Patent number: 6861564
    Abstract: The present invention relates to an improved process for preparing 4-substituted resorcinol derivatives, and intermediate compounds useful in the preparation of such resorcinol derivatives.
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: March 1, 2005
    Assignee: Pfizer Inc.
    Inventors: Stuart Edward Bradley, John Kitchin, Graham Michael Wynne
  • Publication number: 20040186124
    Abstract: Compounds represented by Formula (I): 1
    Type: Application
    Filed: January 6, 2004
    Publication date: September 23, 2004
    Inventors: Graham Michael Wynne, Kevin Doyle, Saleh Ahmed, An-Hu Li, John Fraser Keily, Chrystelle Marie Rasamison, Neil Anthony Pegg, Imaad Saba, Claire Thomas, Don Smyth, Shazia Sadiq, Gary Newton, Graham Dawson, Andrew Phillip Crew, Arlindo Lucas Castelhano
  • Publication number: 20030088113
    Abstract: The present invention relates to an improved process for preparing 4-substituted resorcinol derivatives, and intermediate compounds useful in the preparation of such resorcinol derivatives.
    Type: Application
    Filed: October 28, 2002
    Publication date: May 8, 2003
    Inventors: Stuart Edward Bradley, John Kitchin, Graham Michael Wynne
  • Patent number: 6504037
    Abstract: The present invention relates to an improved process for preparing 4-substituted resorcinol derivatives, and intermediate compounds useful in the preparation of such resorcinol derivatives.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: January 7, 2003
    Assignee: Warner-Lambert Company
    Inventors: Stuart Edward Bradley, John Kitchin, Graham Michael Wynne
  • Publication number: 20020032352
    Abstract: The present invention relates to an improved process for preparing 4-substituted resorcinol derivatives, and intermediate compounds useful in the preparation of such resorcinol derivatives.
    Type: Application
    Filed: March 8, 2001
    Publication date: March 14, 2002
    Inventors: Stuart Edward Bradley, John Kitchin, Graham Michael Wynne