Patents by Inventor Graham Ogg

Graham Ogg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IDENTIFICATION OF LIGANDS AND THEIR USE
    Publication number: 20210239698
    Abstract: The invention provides carriers and kits for use in the identification of ligands. Carriers of the invention are provided to which is attached a DNA encoding a peptide and a ?2 microglobulin. Carriers of the invention are capable of identifying an epitope recognized by a T-cell receptor and/or an NK-cell receptor and/or an NKT-cell receptor. The invention also provides kits for screening for a T-cell epitope and/or an NK-cell epitope and/or an NKT-cell epitope, wherein the kits comprise a carrier of the invention.
    Type: Application
    Filed: April 15, 2021
    Publication date: August 5, 2021
    Applicant: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Graham Ogg, Li-Chieh Huang, Aamir Aslam
  • IDENTIFICATION AND DISPLAY OF PEPTIDE LIGANDS
    Publication number: 20190323004
    Abstract: A carrier to which is attached a peptide and DNA encoding the peptide, wherein the peptide includes at least one non-natural amino acid and/or wherein the peptide has a constrained secondary structure; or a carrier to which is attached ?2 microglobulin, a peptide, and DNA encoding the peptide, said carrier not bearing an MHC or MHC-like molecule.
    Type: Application
    Filed: June 20, 2019
    Publication date: October 24, 2019
    Applicant: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: GRAHAM OGG, LI-CHIEH HUANG, TERENCE RABBITTS
  • Identification and display of peptide ligands
    Patent number: 10351847
    Abstract: A carrier to which is attached a peptide and DNA encoding the peptide, wherein the peptide includes at least one non-natural amino acid and/or wherein the peptide has a constrained secondary structure; or a carrier to which is attached ?2 microglobulin, a peptide, and DNA encoding the peptide, said carrier not bearing an MHC or MHC-like molecule.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: July 16, 2019
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Graham Ogg, Li-Chieh Huang, Terence Rabbitts
  • ANALYSIS OF T-CELL MONOTYPIA
    Publication number: 20170298445
    Abstract: A method of investigating the monotypia of a population of T-cells comprising detecting expression of the T cell receptor beta chain constant region TRBC1 and TRBC2, and/or the T cell receptor gamma chain constant region TRGC1 and TRGC, in a population of T-cells.
    Type: Application
    Filed: October 2, 2015
    Publication date: October 19, 2017
    Applicant: ISIS Innovation Limited
    Inventor: Graham Ogg
  • IDENTIFICATION OF LIGANDS AND THEIR USE
    Publication number: 20160341727
    Abstract: A method to identify a peptide and/or its encoding DNA, wherein the peptide binds to a T-cell receptor and/or an NK-cell receptor and/or an NKT-cell receptor, the method comprising: providing a carrier to which is attached a peptide and its encoding DNA; providing an MHC and/or an MHC-like molecule; and exposing the peptide to a T-cell receptor and/or an NK-cell receptor and/or an NKT-cell receptor in the presence of the MHC or MHC-like molecule.
    Type: Application
    Filed: January 12, 2016
    Publication date: November 24, 2016
    Inventors: Graham Ogg, Li-Chieh Huang, Aamir Aslam
  • IDENTIFICATION AND DISPLAY OF PEPTIDE LIGANDS
    Publication number: 20160298109
    Abstract: A carrier to which is attached a peptide and DNA encoding the peptide, wherein the peptide includes at least one non-natural amino acid and/or wherein the peptide has a constrained secondary structure; or a carrier to which is attached ?2 micro-globulin, a peptide, and DNA encoding the peptide, said carrier not bearing an MHC or MHC-like molecule.
    Type: Application
    Filed: July 23, 2014
    Publication date: October 13, 2016
    Applicant: Isis Innovation Limited
    Inventors: GRAHAM OGG, LI-CHIEH HUANG, TERENCE RABBITTS
  • IDENTIFICATION OF LIGANDS AND THEIR USE
    Publication number: 20130303380
    Abstract: A method to identify a peptide and/or its encoding DNA, wherein the peptide binds to a T-cell receptor and/or an NK-cell receptor and/or an NKT-cell receptor, the method comprising: providing a carrier to which is attached a peptide and its encoding DNA; providing an MHC and/or an MHC-like molecule; and exposing the peptide to a T-cell receptor and/or an NK-cell receptor and/or an NKT-cell receptor in the presence of the MHC or MHC-like molecule.
    Type: Application
    Filed: August 17, 2011
    Publication date: November 14, 2013
    Inventors: Graham Ogg, Li-Chieh Huang, Aamir Aslam