Abstract: A hookstrip screen assembly for use in a shaker is disclosed. The hookstrip screen assembly includes a filtering element and a composite frame further including a top surface, a bottom surface, and a plurality of filtering element attachment points. Also, the filtering element is attached to the plurality of filtering element attachment points. In another aspect, a method of forming a hookstrip screen assembly for use in a shaker. The method of forming a hookstrip screen assembly includes forming a wire structure, molding a composite frame incorporating the wire structure and forming a plurality of filtering element attachment points on the composite frame. The method also includes attaching a filtering element to the plurality of filtering element attachment points on the composite frame.

Abstract: A shaker screen including a sealing element and a composite frame, wherein the sealing element is attached to a basal perimeter of the composite is disclosed. Furthermore, a method of forming a shaker screen including forming a sealing element, forming a composite frame, and attaching the sealing element to the composite frame, wherein the sealing element is disposed along at least one surface of a basal perimeter of the composite frame is disclosed. Also, a shaker screen attachment including a sealing element, a composite frame, and a wedge is disclosed. The shaker screen attachment further includes wherein the sealing element is attached to a basal perimeter of the composite frame, and wherein the wedge is disposed between the composite frame and a shaker basket such that the sealing element compresses against the shaker basket.

Abstract: A system including a first screen having a first frame and a first sealing element attached to an outer perimeter of the first frame, and a second screen disposed adjacent the first screen, the second screen having a second frame and a second sealing element attached to an outer perimeter of the second frame, wherein the first sealing element and the second sealing element provide a seal between the first screen and the second screen is disclosed. Further, a method of forming a screen frame including forming a frame and attaching a sealing element to an outer perimeter of the frame is disclosed. Additionally, a shaker screen including a frame and a sealing element attached to an outer perimeter of the frame, wherein the sealing element is attached by one selected from thermal bonding and co-molding is disclosed.

Abstract: A screen for use in a vibratory machine for separating particulate material from liquid material comprising a rigid rectangular support frame having flanges along all four edges to which screen cloths of the type described are bonded with the longer dimension of the rectangular openings defined by the warp and weft wires of the cloth parallel to the longer dimension of the frame. The frame includes an array orthogonal rigid interstices defining a plurality of similar sized rectangular openings or window and the cloths are also bonded to the interstices for the purpose of maintaining the length to width ratio of the openings in the cloths defined by the warp and weft wires thereof. The warp and weft wires of the cloths are tensioned before being bonded to the flanges and interstices.

Abstract: A frame over which woven wire mesh is to be stretched and secured to form a sieving screen and which can be used to screen solids from drilling mud recovered from down-hole when drilling for oil or gas. The frame is a rectilinear moulded plastics frame having edge regions by which it is secured in place in a shaker. Within the frame is a plurality of rectilinear windows formed by an orthogonal array of intersecting ribs also of moulded plastics material. Some of the ribs are internally reinforced by rigid metal members which extend orthogonally between hollow box-section members which define a sub-frame for reinforcing the four edge regions of the frame. The orthogonal members are secured at their ends to the sub-frame. The ends of the sub-frame members are joined at the four corners of the sub-frame. In this way not are only the edge regions of the frame reinforced internally but so also are some of the orthogonally intersecting ribs, so as thereby to produce a rigid frame for the screen.

Abstract: A screen is described for use in a vibrating machine for separating solids from liquid material, comprising woven wire cloth of orthogonal warp and weft wires, tensioned and bonded to a support structure defining at least one rectangular opening across which the cloth extends. The orientation of the cloth is chosen so that the warp wires extend across the width (i.e. shorter dimension) of the or each opening. A method of manufacturing two screens side by side in a jig involves laying a length of woven wire cloth across two rectangular frames laid side by side in the jig with longer edges thereof abutting, and orientating the cloth so that the warp wires extend continuously across the two screens. The cloth is bonded to the frames after which it is severed along the join and surplus cloth is trimmed away from the edges of the frame.

Abstract: A woven wire cloth screen is described in which at least one fine mesh cloth overlies a coarser mesh backing cloth and an additional coarser mesh cloth is secured over the fine mesh cloth, whose mesh and wire size at least are selected so as in general to prevent relatively large abrasive particles from making contact with the fine mesh cloth. Two fine mesh cloths may be sandwiched between the coarser cloths. In one screen the backing cloth is 30#×01.280 mm diameter S/S wire, the upper fine mesh is 180#×0.030 mm diameter S/S wire, the lower fine mesh is 160#×0.036 mm diameter S/S wire, and the additional top cloth is 30#×60#×0.160 mm diameter S/S wire. A method of making such a screen is described in which the cloths are in turn laid over a rigid frame to which they are to be bonded and the tension in the wire mesh cloths is achieved using pneumatically powered rams acting on clamps which grip the edges of the cloths.

Abstract: A screen for use in a vibratory machine for separating particulate material from liquid material comprising a rigid rectangular support frame having flanges along all four edges to which screen cloths of the type described are bonded with the longer dimension of the rectangular openings defined by the warp and weft wires of the cloth parallel to the longer dimension of the frame. The frame includes an array orthogonal rigid interstices defining a plurality of similar sized rectangular openings or window and the cloths are also bonded to the interstices for the purpose of maintaining the length to width ratio of the openings in the cloths defined by the warp and weft wires thereof. The warp and weft wires of the cloths are tensioned before being bonded to the flanges and interstices.

Abstract: The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steriod, on the regulation of expression of the CYP3A4 gene in a human.

Abstract: A method of plugging an area of damaged mesh in a sifting screen. The method is applicable to screens in which woven wire mesh is stretched, tensioned and secured over a supporting frame containing a plurality of windows and in which local damage to the mesh is in an area of the mesh which overlies one of the windows. The method has the steps of inserting into the window a device which is a close fit therein, and securing the device in the window so as to completely cover the area of damaged mesh. The device may be a former having stretched thereacross and secured thereto mesh similar to that stretched across the window in question, or simply a plate or block. The device may be secured in place by a force or interference fit, mechanical means, or adhesive, or the device may be resiliently deformable to allow it to be pushed past a projection in the window, so as to snap fit the device in place.

Abstract: A screen is described wherein one end of the screen frame is provided with an upwardly open channel profile and the other end with a similar but downwardly open channel profile, such that the outboard edge of an upwardly open profile will fit within the channel of a downwardly open profile provided along the edge of an adjoining screen frame, to enable two such screens to be connected together and to enable linear movement in a direction generally perpendicular to the line of engagement and generally in the plane of at least one of the two screens, to be transmitted from one screen frame to the other. The engagement of one profile by another also serves to close the gap between the two screen frames and prevent at least particulate material from passing therebetween. Preferably the engagement prevents liquid from passing therebetween.

Abstract: A screen is described wherein one end of the screen frame is provided with an upwardly open channel profile and the other end with a similar but downwardly open channel profile, such that the outboard edge of an upwardly open profile will fit within the channel of a downwardly open profile provided along the edge of an adjoining screen frame, to enable two such screens to be connected together and to enable linear movement in a direction generally perpendicular to the line of engagement and generally in the plane of at least one of the two screens, to be transmitted from one screen frame to the other. The engagement of one profile by another also serves to close the gap between the two screen frames and prevent at least particulate material from passing therebetween. Preferably the engagement prevents liquid from passing therebetween.

Abstract: A method of plugging an area of damaged mesh in a sifting screen is described. The method is applicable to screens of the type in which woven wire mesh is stretched, tensioned and secured over a supporting frame containing a plurality of windows and in which local damage to the mesh is in an area of the mesh which overlies one of the windows. The method comprises the steps of inserting into the window a device which is a close fit therein, and securing the device in the window so as to completely cover the area of damaged mesh. The device may comprise a former having stretched thereacross and secured thereto mesh similar to that stretched across the window in question, or simply a plate or block. The device may be secured in place by a force or interference fit, mechanical means, or adhesive, or the device may be resiliently deformable to allow it to be pushed past a projection in the window, so as to snap fit the device in place.