Abstract: The present disclosure provides apparatuses and computer readable media for measuring sub-epidermal moisture in patients to determine damaged tissue for clinical intervention. The present disclosure also provides methods for determining damaged tissue.

Abstract: A gravel pack system has a heel section and a toe section that is downhole from the heel section. The system also includes a conveyance having an interior passageway for fluid flow to the toe section, a closing sleeve that forms an annulus with the conveyance, a shunt having a first section that provides a fluid flow entrance into the shunt, a second section that extends to the heel section along the gravel pack system, and one or more nozzles along the second section that provides fluid flow out of the gravel pack system at the heel section, and a shroud having a first section that is coupled to the closing sleeve and a second section that is coupled to the shunt, where the shroud and the conveyance form a second annulus.

Abstract: This application describes a spatial envelope defining interaction of a robot arm and a fixture. The spatial envelope has a “keep-out” envelope defining a volume that the robot arm shall avoid entering, an input location defining a volume where the robot arm is to place a first object, an output location defining a volume from which the robot arm is to remove a second object, and a plurality of target items.

Abstract: An apparatus for analysis of a sample of a material is disclosed. The apparatus has a body configured to accept the sample and a detector with a plurality of points. The detector is configured to provide a signal about the intensities of light received at the points. The apparatus also includes a slit array having a plurality of slits configured to collected light from the accepted sample and a collimating lens array having a plurality of lenses configured to receive the light from the slit array and collimate the collected light. The apparatus also includes a diffraction grating configured to diffract the light received from the collimating lens array and a focusing lens configured to focus the diffracted light of a common frequency on a common point of the detector.

Abstract: A method of analyzing a sample is disclosed. The method includes the steps of measuring a spectral response of the sample, selecting a reference material having a Raman peak with a magnitude at a wave number, measuring a peak value in the spectral response at the wave number, and determining an amount of the reference material in the sample based in part on a ratio of the measured peak value to the magnitude of the Raman peak of the reference material.

Abstract: This application describes a method of determining a position and orientation of an object having a plurality of fiducials attached thereto. The method includes the steps of forming images of the plurality of fiducials on a sensitive surface of a sensor and determining a 2D location of each of the images of the plurality of fiducials on the sensitive surface. Information comprising 3D positions of the plurality of fiducials in a coordinate system of the object is then retrieved and each of the 2D locations of the plurality of images is associated with the 3D position of the same fiducial. A position and orientation of the object with respect to the sensitive surface of the sensor is then determined based in part on the 2D locations of the images and the 3D positions of the fiducials.

Abstract: The present application describes uses for Pertuzumab, a first-in-class HER2 dimerization inhibitor. In particular, the application describes methods for extending progression free survival in a HER2-positive breast cancer patient population; and combining two HER2 antibodies to treat HER2-positive cancer without increasing cardiac toxicity.

Abstract: The present application describes uses for Pertuzumab, a first-in-class HER2 dimerization inhibitor. In particular, the application describes methods for extending progression free survival in a HER2-positive breast cancer patient population; and combining two HER2 antibodies to treat HER2-positive cancer without increasing cardiac toxicity.

Abstract: A gravel pack system has a heel section and a toe section that is downhole from the heel section. The system also includes a conveyance having an interior passageway for fluid flow to the toe section, a closing sleeve that forms an annulus with the conveyance, a shunt having a first section that provides a fluid flow entrance into the shunt, a second section that extends to the heel section along the gravel pack system, and one or more nozzles along the second section that provides fluid flow out of the gravel pack system at the heel section, and a shroud having a first section that is coupled to the closing sleeve and a second section that is coupled to the shunt, where the shroud and the conveyance form a second annulus.

Abstract: An apparatus for analysis of a sample of a material is disclosed. The apparatus has a body configured to accept the sample and a detector with a plurality of points. The detector is configured to provide a signal about the intensities of light received at the points. The apparatus also includes a slit array having a plurality of slits configured to collected light from the accepted sample and a collimating lens array having a plurality of lenses configured to receive the light from the slit array and collimate the collected light. The apparatus also includes a diffraction grating configured to diffract the light received from the collimating lens array and a focusing lens configured to focus the diffracted light of a common frequency on a common point of the detector.

Abstract: A system for connecting a first ship to a second ship, the system having a plurality of target items coupled to the second ship, a camera module coupled to the first ship and configured to provide information comprising positions of images of the target items in a FOV, and a processor coupled to the camera module and a memory and configured to determine a first position and a first orientation of the second ship relative to the first ship.

Abstract: The disclosure generally relates to substituted heterocyclic compounds of Formula (Ia), which are inhibitors of PAD4, method for preparing these compounds, pharmaceutical compositions comprising these compounds and use of these compounds in the treatment of a disease or a disorder associated with PAD4 enzyme activity.

Abstract: An apparatus for analysis of a sample of a material is disclosed. The apparatus includes a holder configured to accept the sample. The holder includes a sample plate having a first surface configured to contact the accepted sample and a sample lens array that comprises a plurality of focusing elements.

Abstract: Methods and apparatus for detecting the retention of a car key by a customer after return of a rental car are disclosed. A plurality of RFID tags having a common identifier are attached to the rental car keys. The shuttle bus or other facility exit is equipped with a detection portal configured to detect a RFID tag having the common identifier and provide a signal upon detection of the RFID tag to a monitor that provides an alert upon receipt of the signal.

Abstract: A system for determining the position and orientation of a landing area relative to an approaching vehicle is disclosed. The landing area has a plurality of target items disposed proximate to the landing area at known locations. The system includes a sensor on which is formed images of target items that are within a Field of View (FOV) of the sensor, a processor configured to receive the positions of the target items on the sensor, and a memory coupled to the processor. The memory stores the locations of the target items relative to the landing area and instructions that, when loaded into the processor and executed, cause the processor to determine a position and an orientation of the landing area relative to the vehicle based in part on the information received from the sensor and the locations of the target items.

Abstract: This application describes fixture having a body and a plurality of fiducials with at least one of the fiducials having a first state and a second state and able to move to one of the first state and the second state. The fiducials are arranged such that knowledge of the 3D positions of the fiducials in an observing coordinate system is sufficient to determine a first position and a first orientation of the body in the observing coordinate system.

Abstract: A method of identifying relationships between data collections is disclosed. Each data collection comprises a plurality of data records made up of data fields. The method comprises performing a relationship search process based on a first seed value and a second seed value. A first set of records from the data collections is identified based on the first seed value. A second set of records from the data collections is identified based on the second seed value. The process then searches for a common value across the first and second record sets, wherein the common value is a value which appears in a first field in a first record of the first record set and in a second field in a second record of the second record set, wherein the first record is from a first data collection and the second record is from a second data collection.

Abstract: A shelving system for replenishing a stock of a product. The shelving system uses gondolas each having a base, a support structure coupled to the base, and a shelf coupled to the support structure. The system has a first configuration that provides access to the front of the shelf but not to the back of the shelf. The system has a second configuration that provides access to the back of the shelf so as to enable replenishment of the stock by adding additional product from the back of the shelf.

Abstract: The present application describes uses for Pertuzumab, a first-in-class HER2 dimerization inhibitor. In particular, the application describes methods for extending progression free survival in a HER2-positive breast cancer patient population; and combining two HER2 antibodies to treat HER2-positive cancer without increasing cardiac toxicity.

Abstract: An apparatus for disinfecting an object is disclosed herein. The apparatus includes an enclosure having an interior, an entrance, an exit, and a path through the interior from the entrance to the exit along which the object travels. The object moves along the path from the entrance to the exit without support from a moving conveyance. The apparatus also includes a light source that is positioned within the interior and configured to emit ultraviolet light such that every exterior surface of object is exposed to the ultraviolet light as the object traverses the interior.