Patents by Inventor Graham S. Leonard

Graham S. Leonard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spray-chilled nabumetone
    Patent number: 5539000
    Abstract: Nabumetone which is spray-chilled and formulated into unit dose forms which have a smaller volume than was previously possible.
    Type: Grant
    Filed: February 22, 1993
    Date of Patent: July 23, 1996
    Assignee: SmithKline Beecham p.l.c.
    Inventor: Graham S. Leonard
  • Pharmaceutical compositions
    Patent number: 5275823
    Abstract: Chewable tablets containing unpleasant tasting medicaments such as cimetidine are provided. The palatability of the tablets is improved by including certain hygroscopic water-insoluble substances as extragranular excipients in amounts corresponding to 5% (w/w) to 15% (w/w) of the table.
    Type: Grant
    Filed: December 23, 1991
    Date of Patent: January 4, 1994
    Assignee: Smith Kline & French Laboratories Ltd.
    Inventors: Gordon France, Graham S. Leonard
  • Pharmaceutical compositions
    Patent number: 5229134
    Abstract: Delayed-release oral dosage forms are described comprising cimetidine or a salt thereof and optionally a buffer that is capable of aiding dissolution of cimetidine in the intestine, coated with a release-delaying substance comprising a coating agent such as Eudragit.RTM. L 30 D.
    Type: Grant
    Filed: December 5, 1990
    Date of Patent: July 20, 1993
    Assignee: Laboratories Smith Kline & French
    Inventors: Jacky Mention, Rene Tarral, Graham S. Leonard
  • Pharmaceutical compositions
    Patent number: 5169640
    Abstract: The invention provides a solid pharmaceutical dosage form comprising:(i) cimetidine; and(ii) antacid, wherein at least part of the antacid is in the form of granules comprising a freely water-soluble solid diluent, the antacid, and a rapidly swellable water-insoluble disintegrant.Compositions of this type overcome the problem of the reduced bioavailability of cimetidine which can occur when cimetidine is co-administered with antacids.
    Type: Grant
    Filed: January 4, 1989
    Date of Patent: December 8, 1992
    Assignee: Smith Kline & French Laboratories, Ltd.
    Inventors: Gordon France, Graham S. Leonard, Kevin E. Pearmain
  • Pharmaceutical formulations
    Patent number: 4996222
    Abstract: The invention provides pharmaceutical suspension compositions of cimetidine wherein substantially all of the cimetidine is in the polymorph B crystalline form.
    Type: Grant
    Filed: March 9, 1990
    Date of Patent: February 26, 1991
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Brian A. C. Carlin, John N. C. Healey, Graham S. Leonard, Geoffrey D. Tovey