Abstract: There is provided a method for a machine learning based method of analysing drug-like molecules by representing the molecular quantum states of each drug-like molecule as a quantum graph, and then feeding that quantum graph as an input to a machine learning system.

Abstract: Provided herein are benzenesulfonamide derivatives having Formula (III), pharmaceutical compositions comprising said compounds, and method for using said compounds for disrupting proteins/polypeptides, protein/polypeptide function, and for the treatment of diseases through the disruption of proteins or polypeptides involved in the etiology of the disease. Said compounds comprise fluorinated benzene sulfonamide structures.

Abstract: Disclosed is a drug release device and uses of such a device. The device comprises a drug release component and a support. The drug release component comprises one or more thermoplastic elastomer (TPE) polymers and one or more drugs wherein at least one of the TPE polymers is a styrenic TPE block co-polymer (TPE-S). The drug release component is impregnated with the one or more drugs and is moulded to the support.

Abstract: The invention provides a retarded acid-curing pre-polymeric composition wherein the composition comprises an acid, a pre-polymer and hydroxylamine; use of hydroxylamine as a retarder for an acid-curing pre-polymer composition; a method of retarding the curing of an acid-curing pre-polymeric composition which method comprises the step of adding hydroxylamine to the pre-polymer to form a pre-polymer mixture; and a method of curing a retarded acid-curing pre-polymeric composition wherein the method comprises the step of heating the composition to an elevated temperature for use in improving processing and controlling reactivity in a wide range of industrial applications.

Abstract: The invention provides an electrolyte comprising an ester-cured alkaline phenolic resole resin containing conducting alkaline salts and methods for the use of the resin.

Abstract: The invention provides a retarded acid-curing pre-polymeric composition wherein the composition comprises an acid, a pre-polymer and hydroxylamine; use of hydroxylamine as a retarder for an acid-curing pre-polymer composition; a method of retarding the curing of an acid-curing pre-polymeric composition which method comprises the step of adding hydroxylamine to the pre-polymer to form a pre-polymer mixture; and a method of curing a retarded acid-curing pre-polymeric composition wherein the method comprises the step of heating the composition to an elevated temperature for use in improving processing and controlling reactivity in a wide range of industrial applications.

Abstract: The invention provides an electrolyte comprising an ester-cured alkaline phenolic resole resin containing conducting alkaline salts and methods for the use of the resin.

Abstract: The invention provides an electrode, electrolyte and/or a separator plate comprising a conductive material-doped ester-cured alkaline phenolic resole resin containing conducting alkaline salts.

Abstract: The invention provides a polymer comprising an acid cured solvented resole wherein the solvented resole is substantially free from water; a shaped article formed from the polymer and use of the polymer as an electrode, as an electromagnetic shielding material, to suppress electromagnetic interference, or to prevent electrostatic discharge at a location; which polymer is conductive.

Abstract: Methods for making articulate detergents are disclosed. The detergent particulates are formed from a combination of pre-formed detergent particulates and other detergent ingredients may also be preformed such as blown powders, extrudates or agglomerates or particulate raw materials. Selection of the feed streams into a low or moderate shear mixing process enable of the finished detergent particle to be controlled without requiring careful control of the conditions.