Patents by Inventor Graham Vesey
Graham Vesey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210260129Abstract: The invention relates to methods for the production of mesenchymal stem cells (MSCs), in particular to methods for the large scale production of MSCs, such as allogeneic MSCs, for use in treating various diseases in humans and other animals. The invention also relates to methods which permit the selection of preferred donor cells suitable for large seal e production of MSCs. The invention also relates to purified MSCs prepared by the methods of the invention. The invention also relates to the use of plate let lysate in methods for preparing cultures of MSCs and to the preparation of extracellular matrix-enriched secretions. The invention also relates to methods for the preparation of compositions comprising one or more component(s) secreted from cultured MSCs, having improved stability characteristics.Type: ApplicationFiled: February 9, 2021Publication date: August 26, 2021Applicant: CELL IDEAS PTY LTDInventors: Balarka Banerjee, Charlotte Morgan, Graham Vesey, Nicolle Hannah Packer
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Patent number: 10967008Abstract: The present invention relates to methods for the preparation of compositions comprising adipose tissue-derived secretions, for example those derived from bovine adipose tissue, and the use of such compositions in the preparation of a pharmaceutical composition for topical use. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of a non-inflammatory condition, for example the treatment of a skin condition, and for the stimulation of hair growth in a subject by topical application. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of acne.Type: GrantFiled: July 11, 2017Date of Patent: April 6, 2021Assignee: Cell Ideas Pty LtdInventors: Graham Vesey, Rebecca Anne Webster
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Publication number: 20200261510Abstract: The invention relates to compositions comprising (i) adipose tissue-derived cell secretions or (ii) an adipose tissue-derived cell suspension, optionally comprising adipocytes, or (iii) a combination of adipose tissue-derived cell secretions and an adipose tissue-derived cell suspension, optionally comprising adipocytes, and to their use in pharmaceutical compositions and methods for treatment of various conditions. The invention also relates to improved methods, agents and compositions for cryopreservation of cells.Type: ApplicationFiled: April 20, 2020Publication date: August 20, 2020Inventors: Graham Vesey, Rebecca Anne Webster, Richard Lilischkis
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Patent number: 10660921Abstract: The invention relates to compositions comprising (i) adipose tissue-derived cell secretions or (ii) an adipose tissue-derived cell suspension, optionally comprising adipocytes, or (iii) a combination of adipose tissue-derived cell secretions and an adipose tissue-derived cell suspension, optionally comprising adipocytes, and to their use in pharmaceutical compositions and methods for treatment of various conditions. The invention also relates to improved methods, agents and compositions for cryopreservation of cells.Type: GrantFiled: September 19, 2018Date of Patent: May 26, 2020Assignee: Cell Ideas Pty Ltd.Inventors: Graham Vesey, Rebecca Anne Webster, Richard Lilischkis
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Publication number: 20190358291Abstract: The present invention relates to the treatment and prevention of cancer. The present invention relates to vaccines comprising solubilized components of cancer cells or cancer-associated cells. Moreover, the present invention also relates to methods of producing vaccines from biological samples comprising cancer cells or cancer-associated cells and using said vaccines for the treatment or prevention of cancer in subjects. The present invention also relates to methods of producing vaccines, in particular, autologous vaccines. The present invention also relates to therapeutic uses of mesenchymal stem cells and to methods of treatment and or prevention that comprise administering mesenchymal stem cells to a subject. The present invention also relates to methods of enhancing the efficacy of vaccines and methods for the treatment and prevention of cancer, and to compositions and kits suitable for use in the methods.Type: ApplicationFiled: June 12, 2019Publication date: November 28, 2019Inventors: Ross Arthur DAVEY, Christopher John WEIR, Graham VESEY
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Publication number: 20190015455Abstract: The invention relates to compositions comprising (i) adipose tissue-derived cell secretions or (ii) an adipose tissue-derived cell suspension, optionally comprising adipocytes, or (iii) a combination of adipose tissue-derived cell secretions and an adipose tissue-derived cell suspension, optionally comprising adipocytes, and to their use in pharmaceutical compositions and methods for treatment of various conditions. The invention also relates to improved methods, agents and compositions for cryopreservation of cells.Type: ApplicationFiled: September 19, 2018Publication date: January 17, 2019Inventors: Graham Vesey, Rebecca Anne Webster, Richard Lilischkis
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Patent number: 10111909Abstract: The invention relates to compositions comprising (i) adipose tissue-derived cell secretions or (ii) an adipose tissue-derived cell suspension, optionally comprising adipocytes, or (iii) a combination of adipose tissue-derived cell secretions and an adipose tissue-derived cell suspension, optionally comprising adipocytes, and to their use in pharmaceutical compositions and methods for treatment of various conditions. The invention also relates to improved methods, agents and compositions for cryopreservation of cells.Type: GrantFiled: September 21, 2012Date of Patent: October 30, 2018Assignee: Cell Ideas Pty LtdInventors: Graham Vesey, Rebecca Anne Webster, Richard Lilischkis
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Publication number: 20180236003Abstract: The invention relates to methods for the production of mesenchymal stem cells (MSCs), in particular to methods for the large scale production of MSCs, such as allogeneic MSCs, for use in treating various diseases in humans and other animals. The invention also relates to methods which permit the selection of preferred donor cells suitable for l arge scal e production of MSCs. The invention also relates to purified MSCs prepared by the methods of the invention. The invention also relates to the use of platelet lysate in methods for preparing cultures of MSCs and to the preparation of extracellular matrix-enriched secretions. The invention also relates to methods for the preparation of compositions comprising one or more component(s) secreted from cultured MSCs, having improved stability characteristics.Type: ApplicationFiled: September 8, 2016Publication date: August 23, 2018Inventors: Balarka Banerjee, Charlotte Morgan, Graham Vesey, Nicolle Hannah Packer
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Publication number: 20180221411Abstract: The present invention relates to methods for the improved treatment of an inflammatory disorder, where the treatment comprises administration of sex-matched stem or progenitor cells, such as mesenchymal stem cells (MSCs), or sex-matched cell secretions, or a combination thereof to a subject. The invention also relates to kits and compositions which may be used in such methods.Type: ApplicationFiled: December 18, 2015Publication date: August 9, 2018Inventors: Graham Vesey, Elizabeth Evans
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Publication number: 20180169151Abstract: The present invention relates to methods for the preparation of compositions comprising adipose tissue-derived secretions, for example those derived from bovine adipose tissue, and the use of such compositions in the preparation of a pharmaceutical composition for topical use. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of a non-inflammatory condition, for example the treatment of a skin condition, and for the stimulation of hair growth in a subject by topical application. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of acne.Type: ApplicationFiled: July 11, 2017Publication date: June 21, 2018Inventors: Graham Vesey, Rebecca Anne Webster
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Patent number: 9778161Abstract: A set of 10 or more standards containing a defined number of particles from 1000 to 1,000,000 wherein the defined number of particles is within a degree of error of 10% or less between each standard of the set.Type: GrantFiled: January 31, 2007Date of Patent: October 3, 2017Assignee: BFT PTY LTDInventors: Graham Vesey, Nick Herman, Charlotte Morgan
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Patent number: 9730964Abstract: The present invention relates to methods for the preparation of compositions comprising adipose tissue-derived secretions, for example those derived from bovine adipose tissue, and the use of such compositions in the preparation of a pharmaceutical composition for topical use. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of a non-inflammatory condition, for example the treatment of a skin condition, and for the stimulation of hair growth in a subject by topical application. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of acne.Type: GrantFiled: March 15, 2012Date of Patent: August 15, 2017Assignee: Cell Ideas Pty Ltd.Inventors: Graham Vesey, Rebecca Anne Webster
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Patent number: 9309300Abstract: An isolated mutated green fluorescent protein (gfp) gene for chromosomal insertion into a bacterium, wherein the gene is capable of being expressed in bacteria and produce sufficient fluorescence under illumination from a UV lamp in a bacterial colony to be seen by the naked eye. A gene cassette for inserting a gene into a chromosome.Type: GrantFiled: August 3, 2012Date of Patent: April 12, 2016Assignees: MACQUARIE UNIVERSITY, BTF PTY LTD.Inventors: Leonardo B. Pinheiro, Peter Bergquist, Moreland Gibbs, Graham Vesey
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Publication number: 20150343040Abstract: The present invention relates to the treatment and prevention of cancer. The present invention relates to vaccines comprising solubilized components of cancer cells or cancer-associated cells. Moreover, the present invention also relates to methods of producing vaccines from biological samples comprising cancer cells or cancer-associated cells and using said vaccines for the treatment or prevention of cancer in subjects. The present invention also relates to methods of producing vaccines, in particular, autologous vaccines. The present invention also relates to therapeutic uses of mesenchymal stem cells and to methods of treatment and or prevention that comprise administering mesenchymal stem cells to a subject. The present invention also relates to methods of enhancing the efficacy of vaccines and methods for the treatment and prevention of cancer, and to compositions and kits suitable for use in the methods.Type: ApplicationFiled: December 24, 2013Publication date: December 3, 2015Inventors: Ross Arthur DAVEY, Christopher John WEIR, Graham VESEY
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Patent number: 9062288Abstract: Provided herein is a use of an adipose tissue-derived cell suspension which comprises adipocytes for the preparation of a pharmaceutical composition for use in the treatment of an inflammatory disorder, a cartilage or bone disorder and/or the alleviation of pain associated with an inflammatory disorder in a mammalian subject. Also provided herein is a method of treating an inflammatory disorder, a cartilage or bone disorder or alleviating pain associated with an inflammatory disorder in a mammalian subject, comprising administering to the subject a pharmaceutical composition which comprises: (i) an adipose tissue-derived cell suspension which comprises adipocytes; or (ii) a cell-free extract which is prepared from an adipose tissue-derived cell suspension, wherein the adipose tissue-derived cell suspension comprises adipocytes, together with a pharmaceutically-acceptable carrier or diluent.Type: GrantFiled: August 20, 2009Date of Patent: June 23, 2015Assignee: Regeneus LTDInventor: Graham Vesey
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Publication number: 20140234272Abstract: The invention relates to compositions comprising (i) adipose tissue-derived cell secretions or (ii) an adipose tissue-derived cell suspension, optionally comprising adipocytes, or (iii) a combination of adipose tissue-derived cell secretions and an adipose tissue-derived cell suspension, optionally comprising adipocytes, and to their use in pharmaceutical compositions and methods for treatment of various conditions. The invention also relates to improved methods, agents and compositions for cryopreservation of cells.Type: ApplicationFiled: September 21, 2012Publication date: August 21, 2014Applicant: Cell Ideas Pty Ltd.Inventors: Graham Vesey, Rebecca Anne Webster, Richard Lilischkis
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Publication number: 20140087001Abstract: The present invention relates to methods for the preparation of compositions comprising adipose tissue-derived secretions, for example those derived from bovine adipose tissue, and the use of such compositions in the preparation of a pharmaceutical composition for topical use. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of a non-inflammatory condition, for example the treatment of a skin condition, and for the stimulation of hair growth in a subject by topical application. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of acne.Type: ApplicationFiled: March 15, 2012Publication date: March 27, 2014Inventors: Graham Vesey, Rebecca Anne Webster
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Publication number: 20130065297Abstract: An isolated mutated green fluorescent protein (gfp) gene for chromosomal insertion into a bacterium, wherein the gene is capable of being expressed in bacteria and produce sufficient fluorescence under illumination from a UV lamp in a bacterial colony to be seen by the naked eye. A gene cassette for inserting a gene into a chromosome.Type: ApplicationFiled: August 3, 2012Publication date: March 14, 2013Inventors: Leonardo B. Pinheiro, Peter Bergquist, Moreland Gibbs, Graham Vesey
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Publication number: 20110293577Abstract: Provided herein is a use of an adipose tissue-derived cell suspension which comprises adipocytes for the preparation of a pharmaceutical composition for use in the treatment of an inflammatory disorder, a cartilage or bone disorder and/or the alleviation of pain associated with an inflammatory disorder in a mammalian subject. Also provided herein is a method of treating an inflammatory disorder, a cartilage or bone disorder or alleviating pain associated with an inflammatory disorder in a mammalian subject, comprising administering to the subject a pharmaceutical composition which comprises: (i) an adipose tissue-derived cell suspension which comprises adipocytes; or (ii) a cell-free extract which is prepared from an adipose tissue-derived cell suspension, wherein the adipose tissue-derived cell suspension comprises adipocytes, together with a pharmaceutically-acceptable carrier or diluent.Type: ApplicationFiled: August 20, 2009Publication date: December 1, 2011Applicant: REGENEUS PTY LTD.Inventor: Graham Vesey
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Publication number: 20110039254Abstract: An isolated mutated green fluorescent protein (gfp) gene for chromosomal insertion into a bacterium, wherein the gene is capable of being expressed in bacteria and produce sufficient fluorescence under illumination from a UV lamp in a bacterial colony to be seen by the naked eye. A gene cassette for inserting a gene into a chromosome.Type: ApplicationFiled: September 12, 2005Publication date: February 17, 2011Inventors: Leonardo B. Pinheiro, Peter Bergquist, Moreland Gibbs, Graham Vesey