Patents by Inventor Granger G. Sutton

Granger G. Sutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and system for the assembly of a whole genome using a shot-gun data set
    Patent number: 6714874
    Abstract: The present invention provides methods and systems for assembling a genome from a shot-gun set of end sequenced DNA fragments. Specifically, the present invention provides a method of determining the genomic sequence (base sequence and orientation) of a complex genome using DNA sequence information generated from a collection of DNA fragments obtained from the genome. The present method is particularly useful in assembling genomes of at least 10 MB (up to 5 GB) and which are made up of at least 5% repetitive DNA sequences (up to 25% repetitive), but can be used also for smaller genomes with a lower percentage of repetitive DNA.
    Type: Grant
    Filed: March 15, 2000
    Date of Patent: March 30, 2004
    Assignee: Applera Corporation
    Inventors: Gene W. Myers, Arthur L. Delcher, Ian M. Dew, Michael J. Flanigan, Saul A. Kravitz, Clark M. Mobarry, Knut Reinert, Karin A. Remington, Granger G. Sutton
  • Human ABH
    Publication number: 20030153738
    Abstract: A human hABH polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of mutations and the treatment of diseases which result from damaged DNA, for example, cancer. Antagonists against such polypeptides and their use as a therapeutic to augment chemotherapy of cancer cells are also disclosed.
    Type: Application
    Filed: December 19, 2002
    Publication date: August 14, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Ying-Fei Wei, Granger G. Sutton
  • Human G-protein coupled receptors
    Publication number: 20030044898
    Abstract: Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.
    Type: Application
    Filed: December 21, 2001
    Publication date: March 6, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Yi Li, Liang Cao, Jian Ni, Reiner Gentz, Carol J. Bult, Granger G. Sutton, Craig A. Rosen