Patents by Inventor Granger G. Sutton
Granger G. Sutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6714874Abstract: The present invention provides methods and systems for assembling a genome from a shot-gun set of end sequenced DNA fragments. Specifically, the present invention provides a method of determining the genomic sequence (base sequence and orientation) of a complex genome using DNA sequence information generated from a collection of DNA fragments obtained from the genome. The present method is particularly useful in assembling genomes of at least 10 MB (up to 5 GB) and which are made up of at least 5% repetitive DNA sequences (up to 25% repetitive), but can be used also for smaller genomes with a lower percentage of repetitive DNA.Type: GrantFiled: March 15, 2000Date of Patent: March 30, 2004Assignee: Applera CorporationInventors: Gene W. Myers, Arthur L. Delcher, Ian M. Dew, Michael J. Flanigan, Saul A. Kravitz, Clark M. Mobarry, Knut Reinert, Karin A. Remington, Granger G. Sutton
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Publication number: 20030153738Abstract: A human hABH polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of mutations and the treatment of diseases which result from damaged DNA, for example, cancer. Antagonists against such polypeptides and their use as a therapeutic to augment chemotherapy of cancer cells are also disclosed.Type: ApplicationFiled: December 19, 2002Publication date: August 14, 2003Applicant: Human Genome Sciences, Inc.Inventors: Ying-Fei Wei, Granger G. Sutton
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Patent number: 6573360Abstract: A human hABH polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of mutations and the treatment of diseases which result from damaged DNA, for example, cancer. Antagonists against such polypeptides and their use as a therapeutic to augment chemotherapy of cancer cells are also disclosed.Type: GrantFiled: April 23, 1999Date of Patent: June 3, 2003Assignee: Human Genome Sciences, Inc.Inventors: Ying-Fei Wei, Granger G. Sutton, III
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Publication number: 20030044898Abstract: Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.Type: ApplicationFiled: December 21, 2001Publication date: March 6, 2003Applicant: Human Genome Sciences, Inc.Inventors: Yi Li, Liang Cao, Jian Ni, Reiner Gentz, Carol J. Bult, Granger G. Sutton, Craig A. Rosen
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Patent number: 6090575Abstract: Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.Type: GrantFiled: June 6, 1995Date of Patent: July 18, 2000Assignee: Human Genome Sciences, Inc.Inventors: Yi Li, Liang Cao, Jian Ni, Reiner Gentz, Carol J. Bult, Granger G. Sutton, III, Craig A. Rosen
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Patent number: 5998164Abstract: Human G-protein coupled receptor or polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.Type: GrantFiled: June 6, 1995Date of Patent: December 7, 1999Assignee: Human Genome Sciences, Inc.Inventors: Yi Li, Liang Cao, Jian Ni, Reiner Gentz, Carol J. Bult, Granger G. Sutton, III, Craig A. Rosen
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Patent number: 5929225Abstract: A human hABH polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of mutations and the treatment of diseases which result from damaged DNA, for example, cancer. Antagonists against such polypeptides and their use as a therapeutic to augment chemotherapy of cancer cells are also disclosed.Type: GrantFiled: February 13, 1998Date of Patent: July 27, 1999Assignee: Human Genome Sciences, Inc.Inventors: Ying-Fei Wei, Granger G. Sutton, III
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Patent number: 5880263Abstract: A human chemotactic protein polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for preventing and/or treating for stem cell mobilization, myeloprotection and neuronal protection, to treat tumors, to promote wound healing, to combat parasitic infection and to regulate hematopoiesis. Also disclosed are antagonists against such polypeptides which may be employed to treat rheumatoid arthritis, lung inflammation, allergy, infectious diseases and to prevent inflammation and atherosclerosis. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases are also disclosed.Type: GrantFiled: October 8, 1996Date of Patent: March 9, 1999Assignee: Human Genome Sciences, Inc.Inventors: Haodong Li, Steven M. Ruben, Granger G. Sutton, III
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Patent number: 5866373Abstract: A human chemotactic protein polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for preventing and/or treating for stem cell mobilization, myeloprotection and neuronal protection, to treat tumors, to promote wound healing, to combat parasitic infection and to regulate hematopoiesis. Also disclosed are antagonists against such polypeptides which may be employed to treat rheumatoid arthritis, lung inflammation, allergy, infectious diseases and to prevent inflammation and atherosclerosis. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases are also disclosed.Type: GrantFiled: June 7, 1995Date of Patent: February 2, 1999Assignee: Human Genome Sciences, Inc.Inventors: Haodong Li, Steven M. Ruben, Granger G. Sutton, III
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Patent number: 5747312Abstract: A human hABH polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of mutations and the treatment of diseases which result from damaged DNA, for example, cancer. Antagonists against such polypeptides and their use as a therapeutic to augment chemotherapy of cancer cells are also disclosed.Type: GrantFiled: January 15, 1997Date of Patent: May 5, 1998Assignee: Human Genome Sciences, Inc.Inventors: Ying-Fei Wei, Granger G. Sutton, III
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Patent number: 5618717Abstract: A human hABH polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of mutations and the treatment of diseases which result from damaged DNA, for example, cancer. Antagonists against such polypeptides and their use as a therapeutic to augment chemotherapy of cancer cells are also disclosed.Type: GrantFiled: June 5, 1995Date of Patent: April 8, 1997Assignee: Human Genome Sciences, Inc.Inventors: Ying-Fei Wei, Granger G. Sutton, III