Abstract: A system for occlusion detection could include a syringe pump for a syringe containing a medication, wherein the syringe includes a plunger and the syringe pump includes a plunger driver. A bendable element could be integrally formed with the plunger driver, and a force sensor could also be integrally formed with the plunger driver. Upon occurrence of an occlusion, the plunger would exert a force backwardly against the bendable element, thereby deflecting the bendable element into contact with the force sensor to thereby generate a signal indicating the occurrence of the occlusion.

Abstract: The subject invention pertains to methods and apparatus for the production and purification of cell products, such as immunoglobulins. One aspect of the invention is an integrated cell culture and purification apparatus for the growth and maintenance of cells and the harvest and purification of cell products, such as immunoglobulins. Thus, the apparatus integrates a cell culture function with a purification function. Other aspects of the invention pertain to an automated method for producing immunogenic compositions such as vaccines.

Abstract: An infusate tubing clamp system for an infusion pump includes at least one movable tubing holder for removably securing a portion of infusate tubing. An actuator is operatively coupled to the at least one movable tubing holder. When the actuator is activated, the at least one movable tubing holder responsively and reversibly moves to a position that compressively clamps the portion of infusate tubing with sufficient force to temporarily and reversibly occlude the infusate tubing.

Abstract: A dose request device for a medicament delivery device can include a housing, a dose request button, a short-range non-contact identifier, a communication interface configured to communicate with the medicament delivery device, and a controller. The short-range non-contact identifier can be configured to be capable of reading an identification code from a tag when the tag is disposed within a first range and not to be able to read the identification code from the tag when the tag is disposed beyond a second range. The controller can be configured and programmed to determine whether the identification code read by the short-range non-contact identifier matches any authorized identification code of a set of one or more authorized identification codes, and if so, and if the dose request button is pressed, the controller can then communicate a dose request to the medicament delivery device via the communication interface.

Abstract: A real-time embedded server system for controlling, in real-time, at least one infusion pump. The embedded server system includes an embedded server including a memory and a processor electrically coupled to the memory and configured to implement a control engine configured to issue control commands to at least one infusion pump, a messaging engine configured to issue messages to and receive messages from at least one infusion pump, an aggregation engine configured to aggregate data related to the operation of the at least one infusion pump, and a networking engine configured to control network access of the embedded server and the at least one infusion pump. A patient care system including at least one embedded server controlling device configured to make patient-specific care decisions and an associated network of devices operably coupled to a patient and configured to be controlled by the at least one controlling device.

Abstract: A medical device includes a placeable control panel and a medical device control module configured to provide at least one of a therapeutic or a patient monitoring function. The placeable control panel can include a surface that includes button markings and a responder wirelessly interrogateable to report at least application information of the placeable control panel. The medical device control module can include an outer surface configured to receive the placeable control panel such that the button markings of placeable control panel are accessible to a user. The medical device control module also can include an interrogator configured to wirelessly interrogate the responder of the placeable control panel for the application information of the placeable control panel and a controller operatively coupled to the interrogator. The controller can be programmed and configured to control the medical device control module in accordance with the application information of the placeable control panel.

Abstract: A medical infusion pump pressure plate alignment system and components that include a chassis, a sensor module, and a pressure plate in various embodiments. The pressure plate has a first end pivotally mounted to the chassis of the control module for pivotal retention and a second end selectively mounted to the chassis of the control module. The pressure plate, hooks or rail contain recessed or projection features configured for receipt of the complementary features of the sensor module. Additional alignment features can include a retaining component incorporated with the hook, a guide feature on the outer surface of the pressure plate, and a kickstand feature attached to the rail.

Abstract: A rotatable electrical connector can include a base housing having a bottom surface, a top housing that is rotatably engaged with the base housing, and a plurality of contact pads that are arranged radially within the base housing. The contact pads each have a top surface and a bottom surface. A plurality of signal pins are individually associated with the plurality of contact pads; and each of the signal pins correspondingly project outwardly from the bottom surface of an associated contact pad and outwardly from the bottom surface of the base housing. A center ground pad, having a top surface and a bottom surface, is provided within the base housing. A ground pin projects outwardly from the bottom surface of the center ground pad and outwardly from the bottom surface of the base housing. A plurality of conductors is arranged radially within the top housing. The conductors individually correspond to the plurality of contact pads within the base housing.

Abstract: A compact medical infusion pump includes a base unit and a compact pump mechanism coupled to the base unit. The compact pump mechanism also includes a carriage member shaped to support a medical syringe, is movable in a first linear direction relative to the base unit, and is fixed to a first guide rod arm. The mechanism further includes a plunger driver shaped to selectively engage a plunger portion of the medical syringe, is moveable in a second linear direction opposite the first linear direction, and is fixed to a second guide rod arm. The mechanism also includes a rotatable drive member that is centrally located with respect to the base unit and is driven by a drive train assembly. The rotatable drive member engages both the first guide rod arm and the second guide rod arm to translate the carriage member and the plunger driver in opposite directions.

Abstract: A combined detectional and positional sensor for a syringe pump. The sensor can comprise a syringe thumbpress clamp that is pivotable so that an engagement pin deflects a linear membrane potentiometer first circuit thus providing a closed switch for detection of a syringe in the pump and a variable signal return for indication of plunger head position. Embodiments of the sensor can be used in relatively large syringe pumps and in relatively small syringe pumps, for example.

Abstract: An infusion planning system providing clinical decision support for dynamic patient treatment scheduling. The infusion planning system includes a graphical user interface and a rescheduling assistance engine. The graphical user interface presents a time schedule display graphically representing a plurality of patient treatments over time including at least one infusion delivery profile graphic associated with an ordered infusion. The rescheduling assistance engine includes a user interface display providing a plurality of selectable schedule updates each comprising a set of recommended changes to the patient treatments in compliance with rules governing the patient treatment. The rescheduling assistance engine also provides a selectable graphical visual preview of each of the selectable schedule updates in some embodiments.

Abstract: A method for associating medical devices is provided. The method can include providing a plurality of medical devices and each of the medical devices can include an accelerometer configured to measure spatial accelerations of the medical device. Each of at least two of the medical devices can measure with its accelerometer an acceleration pattern with respect to time. The method can include comparing for correspondence, according to defined correspondence criteria, the measured acceleration patterns, and associating all of the medical devices that measured acceleration patterns that satisfy the defined correspondence criteria. The method can also include modifying a parameter of each member of a set of devices that are associated.

Abstract: An infusion pump can include a syringe receptacle, a retention mechanism, a drive mechanism, and a keyed lock. The retention mechanism can inhibit removal of the syringe from the receptacle when in an engaged state, and enable removal of the syringe when in a disengaged state. The drive mechanism can include a pusher to selectively couple to a thumb press of the syringe, a motor coupleable to the pusher, and a clutch to couple and decouple the motor to the pusher. The keyed lock can operate in coordination with the retention and drive mechanisms such that, if: the keyed lock is locked, the retention mechanism is in the engaged state, and the pusher is coupled to the thumb press of the syringe, then as long as the keyed lock remains locked, the retention mechanism is constrained to the engaged state and the clutch to the coupled state.

Abstract: A dose request device for a medicament delivery device can include a housing, a dose request button, a short-range non-contact identifier, a communication interface configured to communicate with the medicament delivery device, and a controller. The short-range non-contact identifier can be configured to be capable of reading an identification code from a tag when the tag is disposed within a first range and not to be able to read the identification code from the tag when the tag is disposed beyond a second range. The controller can be configured and programmed to determine whether the identification code read by the short-range non-contact identifier matches any authorized identification code of a set of one or more authorized identification codes, and if so, and if the dose request button is pressed, the controller can then communicate a dose request to the medicament delivery device via the communication interface.

Abstract: A cell culture system for the production of cells and cell derived products includes a reusable instrumentation base device incorporating hardware to support cell culture growth. A disposable cultureware module including a cell growth chamber is removably attachable to the instrumentation base device. The base device includes microprocessor control and a pump for circulating cell culture medium through the cell growth chamber. The cultureware module is removably attached to the instrumentation base device. Cells are introduced into the cell growth chamber and a source of medium is fluidly attached to the cultureware module. Operating parameters are programmed into the microprocessor control. The pump is operated to circulate the medium through the cell growth chamber to grow cells or cell products therein. The grown cells or cell products are harvested from the cell growth chamber and the cultureware module is then disposed.

Abstract: An infusion pump includes a pumping mechanism having at least one sensor and a pump motor and a pump control subsystem configured to control operation of the pumping mechanism, the pump control subsystem including a processor, a memory, and a startup module configured to drive the pump motor at a first rate, receive input from the at least one sensor, and drive the pump motor at a second rate based on the input received from the at least one sensor. Startup algorithms command an infusion pump to reach a targeted delivery rate or steady state in minimal time without requiring priming of the pump line or otherwise engaging in known methods of pump startup analysis.

Abstract: An embodiment of a medication dispenser comprises a drug pump having a control module. A medication dose request device can be in communication with the drug pump. A dispensing device, for dispensing substantially solid medication in response to activation of the medication dose request device, can be in communication with the drug pump.

Abstract: A cell culture system for the production of cells and cell derived products includes a reusable instrumentation base device incorporating hardware to support cell culture growth. A disposable cultureware module including a cell growth chamber is removably attachable to the instrumentation base device. The base device includes microprocessor control and a pump for circulating cell culture medium through the cell growth chamber. The cultureware module is removably attached to the instrumentation base device. Cells are introduced into the cell growth chamber and a source of medium is fluidly attached to the cultureware module. Operating parameters are programmed into the microprocessor control. The pump is operated to circulate the medium through the cell growth chamber to grow cells or cell products therein. The grown cells or cell products are harvested from the cell growth chamber and the cultureware module is then disposed.