Patents by Inventor Grant D. Trobridge

Grant D. Trobridge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10221460
    Abstract: Provided herein are methods for the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient. In particular, gene expression levels of GCOM1, MEX3D, TRPM4, ATPAF1, PTRF, GLYATL1, FLNA, OBSCN, STRA13, WHSC1, ARFGAP3, KDM2A, FAM83H, CLDN7, CNOT6, and B3GNT9 are measured. Kits containing means for the measurement of gene expression as described herein and methods for treatment of prostate cancer are also provided.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: March 5, 2019
    Assignee: Washington State University
    Inventors: Grant D. Trobridge, Arun Kumar Nalla
  • Patent number: 10036039
    Abstract: Provided herein are Cocal vesiculovirus envelope pseudotyped retroviral vectors that exhibit high titers, broad species and cell-type tropism, and improved serum stability. Disclosed Cocal vesiculovirus envelope pseudotyped retroviral vectors may be suitably employed for gene therapy applications and, in particular, for the ex vivo and in vivo delivery of a gene of interest to a wide variety of target cells.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: July 31, 2018
    Assignee: FRED HUTCHINSON CANCER RESEARCH CENTER
    Inventors: Grant D. Trobridge, Hans-Peter Kiem
  • Publication number: 20180066282
    Abstract: Provided herein are Cocal vesiculovirus envelope pseudotyped retroviral vectors that exhibit high titers, broad species and cell-type tropism, and improved serum stability. Disclosed Cocal vesiculovirus envelope pseudotyped retroviral vectors may be suitably employed for gene therapy applications and, in particular, for the ex vivo and in vivo delivery of a gene of interest to a wide variety of target cells.
    Type: Application
    Filed: August 23, 2017
    Publication date: March 8, 2018
    Inventors: Grant D. Trobridge, Hans-Peter Kiem
  • Publication number: 20170183739
    Abstract: Provided herein are methods for the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient. In particular, gene expression levels of GCOM1, MEX3D, TRPM4, ATPAF1, PTRF, GLYATL1, FLNA, OBSCN, STRA13, WHSCl, ARFGAP3, KDM2A, FAM83H, CLDN7, CNOT6, and B3GNT9 are measured. Kits containing means for the measurement of gene expression as described herein and methods for treatment of prostate cancer are also provided.
    Type: Application
    Filed: March 25, 2015
    Publication date: June 29, 2017
    Inventors: Grant D. TROBRIDGE, Arun Kumar NALLA
  • Publication number: 20160244782
    Abstract: Provided herein are Cocal vesiculovirus envelope pseudotyped retroviral vectors that exhibit high titers, broad species and cell-type tropism, and improved serum stability. Disclosed Cocal vesiculovirus envelope pseudotyped retroviral vectors may be suitably employed for gene therapy applications and, in particular, for the ex vivo and in vivo delivery of a gene of interest to a wide variety of target cells.
    Type: Application
    Filed: April 15, 2016
    Publication date: August 25, 2016
    Inventors: Grant D. Trobridge, Hans-Peter Kiem
  • Publication number: 20120164118
    Abstract: Provided herein are Cocal vesiculovirus envelope pseudotyped retroviral vectors that exhibit high titers, broad species and cell-type tropism, and improved serum stability. Disclosed Cocal vesiculovirus envelope pseudotyped retroviral vectors may be suitably employed for gene therapy applications and, in particular, for the ex vivo and in vivo delivery of a gene of interest to a wide variety of target cells.
    Type: Application
    Filed: May 4, 2010
    Publication date: June 28, 2012
    Applicant: Fred Hutchinson Cancer Research Center
    Inventors: Grant D. Trobridge, Hans-Peter Kiem