Patents by Inventor Grant E. Dubois

Grant E. Dubois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020009530
    Abstract: The present invention is a non-caloric or reduced calorie frozen carbonated beverage and a method of making it. The freezing point of a diet beverage syrup is reduced through the use of a freezing point depressant, particularly a Sugar MNS which is used to replace a portion of the known high-potency non-caloric sweetener. The preferred Sugar MNS for use in the beverage and method of the present invention is erythritol.
    Type: Application
    Filed: April 20, 2001
    Publication date: January 24, 2002
    Inventors: Grant E. DuBois, James M. Shepherd, Sandra C. Ryan
  • Patent number: 5098723
    Abstract: A low sodium salt composition suitable as a table salt product which comprises:a. 30 to 90 parts NaCl;b. 5 to 70 parts of a non-gritty bulking agent; andc. 0 to 40 parts of a binder;wherein the bulking agent is coated with the NaCl or the NaCl, bulking agent and, optionally binder are uniformly dispersed in a granule is provided. The composition preferably has a density of less than about 0.6 gram/cc and tastes and handles like ordinary table salt.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: March 24, 1992
    Inventors: Grant E. DuBois, Josef Tsau
  • Patent number: 5098724
    Abstract: A low sodium salt composition contains NaCl, a bulking agent and optionally a binder. The composition preferably has a density of less than about 0.6 gram/cc and tastes, handles and flows like a table salt.
    Type: Grant
    Filed: September 15, 1989
    Date of Patent: March 24, 1992
    Inventors: Grant E. DuBois, Josef Tsau
  • Patent number: 4454290
    Abstract: Analogs of the glycoside stevioside are disclosed. These materials have the formula ##STR1## wherein R is a simple physiologically acceptable noncarbohydrate polar organic group. The analogs are sweet and find use as sweeteners.
    Type: Grant
    Filed: June 11, 1981
    Date of Patent: June 12, 1984
    Assignee: Dynapol
    Inventor: Grant E. DuBois
  • Patent number: 4404367
    Abstract: Glucosubstituented diterpenoid compounds analogous to stevioside, rebaudosides C and A, steviolmonoside and steviolbioside but having their gluco units substituted with simple monoglycosidic polar groups and optionally having their C.sub.19 carboxyls as simple esters are disclosed. These materials are sweet and do not degrade under mammalian GI tract conditions.
    Type: Grant
    Filed: August 26, 1981
    Date of Patent: September 13, 1983
    Assignee: Dynapol
    Inventors: Rebecca A. G. Stephenson, Paul S. Dietrich, Grant E. DuBois, Leonard A. Bunes
  • Patent number: 4402990
    Abstract: Analogs of the glycoside stevioside are disclosed. These materials have the formula ##STR1## wherein R is a simple physiologically acceptable noncarbohydrate polar organic group. The analogs are sweet and find use as sweeteners.
    Type: Grant
    Filed: August 26, 1981
    Date of Patent: September 6, 1983
    Assignee: Dynapol
    Inventor: Grant E. DuBois
  • Patent number: 4381402
    Abstract: Analogs of the glycoside stevioside are disclosed. These materials have the formula ##STR1## wherein R.sub.1 and R.sub.2 are as follows:______________________________________ R.sub.1 R.sub.2 ______________________________________ (CH.sub.2).sub.3 SO.sub.3.sup.- M.sup.+ .beta.-D-Sophorose (CH.sub.2).sub.3 SO.sub.3.sup.- M.sup.+ (CH.sub.2).sub.3 SO.sub.3.sup.- M.sup.+ H (CH.sub.2).sub.3 SO.sub.3.sup.- M.sup.+ ______________________________________and M.sup.+ is a physiologically acceptable alkali metal cation.
    Type: Grant
    Filed: December 17, 1981
    Date of Patent: April 26, 1983
    Assignee: Dynapol
    Inventor: Grant E. DuBois
  • Patent number: 4353889
    Abstract: Analogs of the glycoside rebaudioside A are disclosed. These materials have the formula ##STR1## wherein R is a simple physiologically acceptable noncarbohydrate polar organic group. The analogs are sweet and find use as sweeteners.
    Type: Grant
    Filed: June 11, 1981
    Date of Patent: October 12, 1982
    Assignee: Dynapol
    Inventor: Grant E. DuBois
  • Patent number: 4348333
    Abstract: Dihydrochalcones of the formula ##STR1## are disclosed wherein M.sup.+ is a physiologically acceptable cation, X is H or OH, R is a lower alkyl and R' is ##STR2## and n and q, respectively, may have a numerical value of 1 to 6. These materials are useful as sweeteners for edibles.
    Type: Grant
    Filed: October 9, 1981
    Date of Patent: September 7, 1982
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventor: Grant E. DuBois
  • Patent number: 4332830
    Abstract: Analogs of the glycoside stevioside are disclosed. These materials have the formula ##STR1## wherein R.sub.1 and R.sub.2 are as follows:______________________________________ R.sub.1 R.sub.2 ______________________________________ --(CH.sub.2).sub.3 SO.sub.3.sup.- M.sup.+ .beta.-D--Sophorose --(CH.sub.2).sub.3 SO.sub.3.sup.- M.sup.+ --(CH.sub.2).sub.3 SO.sub.3.sup.- M.sup.+ --H --(CH.sub.2).sub.3 SO.sub. 3.sup.- M.sup.+ ______________________________________and M.sup.+ is a physiologically acceptable alkali metal cation.
    Type: Grant
    Filed: September 22, 1980
    Date of Patent: June 1, 1982
    Assignee: Dynapol
    Inventor: Grant E. DuBois
  • Patent number: 4290975
    Abstract: Primary amines are selectively sulfamated by the two-step process of:A. Contacting the amine in liquid phase at low to moderate temperatures with catechol sulfate thereby forming a catechol sulfate addition product, andB. Hydrolyzing the catechol sulfate addition product to the desired sulfamate by contacting it at elevated temperature with a strong base in liquid phase.
    Type: Grant
    Filed: April 14, 1980
    Date of Patent: September 22, 1981
    Inventor: Grant E. DuBois
  • Patent number: 4283434
    Abstract: Sulfamo dihydrochalcones of the formula ##STR1## are disclosed wherein M.sup.+ is a physiologically acceptable cation, X is H or OH, and R is a lower alkyl. These materials are useful as sweeteners for edibles. They may be prepared by sulfonating the corresponding amino dihydrochalcone using, for example, catechol sulfate.
    Type: Grant
    Filed: April 14, 1980
    Date of Patent: August 11, 1981
    Inventors: Grant E. DuBois, Rebecca A. G. Stephenson
  • Patent number: 4267165
    Abstract: Dihydrochalcones of the formula ##STR1## are disclosed wherein X is H or OH and R is a lower alkyl. These materials are useful as sweeteners for edibles. A process for preparing these compounds using a novel intermediate is disclosed as are acid and base neutralization products of the subject dihydrochalcones.
    Type: Grant
    Filed: December 12, 1979
    Date of Patent: May 12, 1981
    Assignee: Dynapol
    Inventors: Grant E. DuBois, Rebecca A. G. Stephenson, Guy A. Crosby
  • Patent number: 4226804
    Abstract: Dihydrochalcones of the formula ##STR1## are disclosed wherein X is H or OH and R is lower alkyl. These materials are useful as sweeteners for edibles. A process for preparing these compounds using a novel intermediate is disclosed as are acid and base neutralization products of the subject dihydrochalcones.
    Type: Grant
    Filed: March 9, 1979
    Date of Patent: October 7, 1980
    Assignee: Dynapol
    Inventors: Grant E. DuBois, Rebecca A. G. Stephenson, Guy A. Crosby
  • Patent number: 4129599
    Abstract: Method is provided for cyclization of polyunsaturated substituted acylic or monocarbocyclic initiator group containing compound having an endocyclic double bond with a chalcogen atom in the allylic position of the initiator group and having at least two sites of unconjugated aliphatic unsaturation in the side chain substituent on the ring. The polyunsaturated compound is cyclized in the presence of a strong acid in a protic solvent which is inert to the acid, preferably a hydroxylic solvent. Mild temperatures and varying times are employed. The products are useful primarily as intermediates for naturally occurring and synthetic steroids. By appropriate substitution of the side chain, the steroidial products are provided with the substituent at C-11, which upon cyclization results in the alpha-configuration. By resolution of the intermediates prior to cyclization, optically active steroids can be obtained.
    Type: Grant
    Filed: June 23, 1977
    Date of Patent: December 12, 1978
    Assignee: The Board of Trustees of Leland Stanford Jr. University
    Inventors: Sina Escher, Grant E. Dubois
  • Patent number: 4064185
    Abstract: Compositions are provided as well as methods for preparing the compositions which serve as cyclization precursors for the preparation of C-11 alkenyl substituted steroids and nor-steroids. The alkenyl group may be converted after cyclization to a variety of heterosubstituents to provide heterofunctionalized C-11 steroids and nor-steroids. The compounds are provided having an initiator group, which has a chalcoxy atom in juxtaposition to a double bond, an olefinically unsaturated linking group and a terminating group which acts to from a carbocation which reacts with a nucleophile to provide a stable product. The C-11 substituent is found to provide upon cyclization the alpha-configuration, so that the subject compounds provide a direct route to the difficultly accessible alpha-C-11 substituted steroids, or, if desired, the alpha-configuration can be inverted to the beta-configuration.
    Type: Grant
    Filed: April 28, 1975
    Date of Patent: December 20, 1977
    Assignee: The Board of Trustees of Leland Stanford Junior University
    Inventors: William S. Johnson, Grant E. Dubois
  • Patent number: 4055678
    Abstract: Dihydrochalcones of the formula ##STR1## derivatizing group, Y is a polar group, X is hydrogen or hydroxyl and R is a lower alkyl, their preparation and their use as non-sugar sweeteners are disclosed.
    Type: Grant
    Filed: January 12, 1976
    Date of Patent: October 25, 1977
    Assignee: Dynapol
    Inventors: Guy A. Crosby, Grant E. DuBois
  • Patent number: 4025535
    Abstract: Flavanones represented by the formula ##STR1## wherein R is a lower alkyl of from one to three carbon atoms inclusive, n is an integer of from one to three inclusive and M is hydrogen or a physiologically acceptable metal cation, are disclosed. These materials are themselves useful as dietetic sweeteners as well as being direct intermediates for the preparation of useful dihydrochalcone sweeteners.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: May 24, 1977
    Assignee: Dynapol Corporation
    Inventors: Guy A. Crosby, Grant E. DuBois, Ned M. Weinshenker
  • Patent number: 3976790
    Abstract: A group of novel dihydrochalcone compounds represented by the formula ##SPC1##Wherein M is hydrogen or a pharmacologically acceptable cation and R is a lower saturated alkyl of from 1 to 4 carbon atoms, and their use as sweetening agents in food products are disclosed.
    Type: Grant
    Filed: June 10, 1974
    Date of Patent: August 24, 1976
    Assignee: Dynapol
    Inventors: Guy A. Crosby, Grant E. DuBois
  • Patent number: 3976687
    Abstract: Dihydrochalcones of the formula ##SPC1##Wherein D is a derivatizing group, Y is a polar group, X is hydrogen or hydroxyl and R is a lower alkyl, their preparation and their use as non-sugar sweeteners are disclosed.
    Type: Grant
    Filed: June 10, 1974
    Date of Patent: August 24, 1976
    Assignee: Dynapol
    Inventors: Guy A. Crosby, Grant E. DuBois