Abstract: Disclosed are methods, systems, and devices for generating sleep predicators to avoid preventable mental episodes from breaking through, thereby averting an irreversible brain damage to a patient, that may be caused by such future mental episodes. In one embodiment, the present invention is a method comprising: acquiring biomedical data from a patient by using a means of signal acquisition; forming a database of the biomedical records in which the database further comprises a sleep prediction algorithm, psychiatric records, and a statistical engine to compute the data and the psychiatric records using the algorithm; mapping the acquired data in reference to the sleep prediction algorithm; validating the sleep predictors; and providing an output of the sleep predicators to a patient or caretaker. The present invention can be used to treat mania, depression, bipolar disorder, schizophrenia, PTSD, anxiety, and other chronic mental health conditions.