Patents by Inventor Grant Logan
Grant Logan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11783952Abstract: Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design.Type: GrantFiled: December 14, 2021Date of Patent: October 10, 2023Assignee: Lawrence Livermore National Security, LLCInventors: Lindsay John Perkins, Jim H. Hammer, John H. Moody, Max Tabak, Burl Grant Logan
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Publication number: 20220193232Abstract: The present invention provides compositions and methods for treating KMA-expressing malignancies including chimeric antigen receptors (CARs) and T cells containing CARs (CAR T-cells). The invention also provides methods and compositions comprising CAR T-cells co-expressing other anti-tumoral agents including cytokines and antibodies.Type: ApplicationFiled: February 28, 2022Publication date: June 23, 2022Inventors: Kenneth MICKLETHWAITE, Rosanne DUNN, David GOTTLIEB, Grant LOGAN
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Patent number: 11305011Abstract: The present invention provides compositions and methods for treating KMA-expressing malignancies including chimeric antigen receptors (CARs) and T cells containing CARs (CAR T-cells). The invention also provides methods and compositions comprising CAR T-cells co-expressing other anti-tumoral agents including cytokines and antibodies.Type: GrantFiled: April 25, 2016Date of Patent: April 19, 2022Assignee: HAEMALOGIX PTY. LTD.Inventors: Kenneth Micklethwaite, Rosanne Dunn, David Gottlieb, Grant Logan
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Publication number: 20220108807Abstract: Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design.Type: ApplicationFiled: December 14, 2021Publication date: April 7, 2022Inventors: Lindsay John Perkins, Jim H. Hammer, John H. Moody, Max Tabak, Burl Grant Logan
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Patent number: 11227693Abstract: Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design.Type: GrantFiled: October 5, 2018Date of Patent: January 18, 2022Assignee: Lawrence Livermore National Security, LLCInventors: Lindsay John Perkins, Jim H. Hammer, John H. Moody, Max Tabak, Burl Grant Logan
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Patent number: 11104917Abstract: The present disclosure relates generally to promoters derived from the AAV anti-sense strand, their use in the expression of one or more heterologous coding sequences, and isolated polynucleotides, vectors and recombinant viruses comprising the promoters. The present disclosure also relates to enhancers derived from the AAV anti-sense strand, their use in increasing the expression of one or more heterologous coding sequences, and isolated polynucleotides, vectors and recombinant viruses comprising the enhancers.Type: GrantFiled: May 4, 2016Date of Patent: August 31, 2021Assignees: CHILDREN'S MEDICAL RESEARCH INSTITUTE, THE SYDNEY CHILDREN'S HOSPITALS NETWORK (RANDWICK AND WESTMEAD) (INCORPORATING THE ROYAL ALEXANDRA HOSPITAL FOR CHILDREN)Inventors: Grant Logan, Ian Alexander, Allison Dane
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Publication number: 20190066851Abstract: Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design.Type: ApplicationFiled: October 5, 2018Publication date: February 28, 2019Inventors: Lindsay John Perkins, Jim H. Hammer, John H. Moody, Max Tabak, Burl Grant Logan
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Patent number: 10134491Abstract: Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design.Type: GrantFiled: May 15, 2014Date of Patent: November 20, 2018Assignee: Lawrence Livermore National Security, LLCInventors: Lindsay John Perkins, Jim H. Hammer, John D. Moody, Max Tabak, George Beedon Zimmerman, Burl Grant Logan
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Publication number: 20180228892Abstract: The present invention provides compositions and methods for treating KMA-expressing malignancies including chimeric antigen receptors (CARs) and T cells containing CARs (CAR T-cells). The invention also provides methods and compositions comprising CAR T-cells co-expressing other anti-tumoral agents including cytokines and antibodies.Type: ApplicationFiled: April 25, 2016Publication date: August 16, 2018Inventors: Kenneth Micklethwaite, Rosanne Dunn, David Gottlieb, Grant Logan
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Publication number: 20180142260Abstract: The present disclosure relates generally to promoters derived from the AAV anti-sense strand, their use in the expression of one or more heterologous coding sequences, and isolated polynucleotides, vectors and recombinant viruses comprising the promoters. The present disclosure also relates to enhancers derived from the AAV anti-sense strand, their use in increasing the expression of one or more heterologous coding sequences, and isolated polynucleotides, vectors and recombinant viruses comprising the enhancers.Type: ApplicationFiled: May 4, 2016Publication date: May 24, 2018Inventors: Grant Logan, Ian Alexander
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Publication number: 20140348283Abstract: Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design.Type: ApplicationFiled: May 15, 2014Publication date: November 27, 2014Inventors: Lindsay John Perkins, Jim H. Hammer, John D. Moody, Max Tabak, George Beedon Zimmerman, Burl Grant Logan
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Publication number: 20080108965Abstract: A sanitary diaper changing kit includes a package, a pair of disposable gloves in the package, and a re-sealable disposal bag in the package. Alternatively, the kit may include other materials such as small single-use package of moist wipes or towelettes, a small single-use package of antiseptic wipes, a small single use package of petroleum jelly and a small single-use package of powder. The sanitary diaper changing kit may be packaged and sold with a disposable diaper, or may be sold separately from diapers to be used in conjunction with a disposable diaper. The kit allows the person changing the diaper to be isolated from the contaminated diaper during the diaper changing operation and provides a convenient means by which the soiled diaper and other used or soiled materials may be disposed of in a sanitary procedure and diaper wearer remains isolated from care giver.Type: ApplicationFiled: October 11, 2006Publication date: May 8, 2008Inventors: William Michael Christensen, Thomas George Petredis, Grant Logan
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Patent number: 5043739Abstract: The invention provides an inexpensive array of rectifying antennas which employ field emission diodes for rectifying electromagnetic waves of microwave frequencies and higher frequencies.Type: GrantFiled: January 30, 1990Date of Patent: August 27, 1991Assignee: The United States of America as represented by the United States Department of EnergyInventors: B. Grant Logan, William J. Orvis
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Patent number: 4252608Abstract: The invention provides a method and apparatus for raising the potential of a magnetic mirror cell by pumping charged particles of the opposite sign of the potential desired out of the mirror cell through excitation, with the pumping being done by an externally imposed field at the bounce frequency of the above charged particles. These pumped simple mirror cells then provide end stoppering for a center mirror cell for the tandem mirror plasma confinement apparatus. For the substantially complete pumping case, the end plugs of a tandem mirror can be up to two orders of magnitude lower in density for confining a given center mirror cell plasma than in the case of end plugs without pumping. As a result the decrease in recirculating power required to keep the system going, the technological state of the art required, and the capital cost are all greatly lowered.Type: GrantFiled: March 16, 1979Date of Patent: February 24, 1981Assignee: The United States of America as represented by the United States Department of EnergyInventors: David E. Baldwin, B. Grant Logan
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Patent number: 4127442Abstract: Method and apparatus for cooling a plasma of warm charged species confined in the center mirror cell of the tandem mirror apparatus by injecting cold neutral species of the plasma into at least one mirroring region of the center mirror cell, the cooling due to the loss of warm charged species through charge exchange with the cold neutral species with resulting diffusion of the warm neutral species out of the plasma.Type: GrantFiled: June 16, 1977Date of Patent: November 28, 1978Assignee: The United States of America as represented by the United States Department of EnergyInventor: B. Grant Logan