Abstract: In accordance the present invention, a method, apparatus and computer program for monitoring air pressure change are provided that may include receiving a user input selecting a pressure monitoring application, receiving a user input initiating monitoring of an ambient air pressure by the pressure monitoring application, determining a first barometric pressure of the ambient air pressure at a first time, determining a second barometric pressure of the ambient air pressure at a second time, wherein the second time is a predetermined time interval from the first time, comparing the first barometric pressure with the second barometric pressure to determine a first absolute rate of change of the ambient air pressure over the predetermined time interval, and providing an indication to employ protective measures when the first absolute rate of change of the ambient air pressure is equal to or a exceeds a threshold rate of change likely to cause barotrauma.

Abstract: Disclosed herein are computer implemented methods of distinguishing ischemic stroke, hemorrhagic stroke, and stroke mimic by detecting circulating biomarkers in a subject. Also provided herein are systems, kits, and methods for the detecting.

Abstract: Provided herein are computer implemented methods of evaluating, detecting, and identifying biomarkers of blood brain barrier disruption. Also provided herein are kits and methods for detecting blood brain barrier disruption in a subject.

Abstract: Provided herein are methods, kits, and devices for detecting ischemic stroke and identifying biomarkers of ischemic stroke. Evaluating the expression patterns of ischemic stroke biomarkers in biological samples can allow for the diagnosis of stroke in a time-sensitive and bedside manner.