Abstract: Fourier Transform Raman Spectroscopy (FT-Raman) determines the isomer ratio of chemical compositions.

Abstract: The invention provides magnesium S-omeprazolato compounds according to formula (I): [Mg(solva)x(solvb)y][Mg(S-omeprazolato)3]2.(solvc)z??(I), pharmaceutical compositions and processes of making the same. In formula (I), solva, solvb, and solvc represent solvent molecules where x and y are independently selected from integers 0 to 6, the sum of which is 4 or 6, while z is a positive rational number from 0 to 6. The compounds are useful for the treatment of gastric acid related conditions and the inhibition of gastric acid secretion.

Abstract: The invention provides magnesium S-omeprazolato coordination compounds according to formula (I): [Mg(solva)x(solvb)y][Mg(S-omeprazolato)3]2.(solvc)z??(I), pharmaceutical compositions and processes of making the same. In formula (I), solva, solvb, and solvc represent solvent molecules where x and y are independently selected from integers 0 to 6, the sum of which is 4 or 6, while z is a positive rational number from 0 to 6. The compounds are useful for the treatment of gastric acid related conditions and the inhibition of gastric acid secretion.

Abstract: The present invention provides an ion pair compound of the formula [narcotic]+[A]?, wherein [narcotic]+ represents at least one cation of at least one narcotic agent or one or more stereochemical isomers thereof and [A]? represents at least one anion of at least one NSAID or one or more stereochemical isomers thereof. An example of the ion pair compound is propoxyphene diclofenate. The ion pair compounds, or their pharmaceutical compositions, are useful in methods of treating a wide variety of conditions that indicate analgesics, anti-inflammatory agents, or both. Under the conditions prescribed for their use, the ion pair compounds exhibit poor or complete insolubility but excellent chemical stability in low pH environments, such as those found in the stomach. The ion pair compounds readily dissolve and dissociate in higher pH environments such as the small intestine to release the constituent narcotic and NSAID.

Abstract: Fourier Transform Raman Spectroscopy (FT-Raman) determines the isomer ratio of chemical compositions.

Abstract: The invention encompasses neutral dithiocarbamate metal compounds and methods of treating cancer using such compounds, along with methods for sensitizing AIDS/HIV patients to anti-retroviral therapy by blocking the P-glycoprotein membrane toxin extrusion pump using such compounds. Compounds inhibit the growth of cancer cells of a variety of cell types. A method is presented for using the neutral compounds disclosed herein, amongst other uses disclosed herein, to reduce tumor growth, and to potentiate the effect of other anticancer agents. The invention also encompasses pharmaceutical compositions comprising the neutral compounds and a pharmaceutically acceptable excipient, diluent, solubilizer, solvent, adjuvant or carrier, or a mixture thereof.