Abstract: A prosthetic heart valve system may include a collapsible anchor frame which may include a support frame that has a central portion, and atrial and ventricular portions flared radially outwardly from the central portion. The atrial and ventricular portions may be sized to sandwich or clamp an annulus of the heart valve. An atrial sheet may be coupled to the atrial portion of the support frame and may extend radially inwardly to a central aperture in the atrial sheet, the atrial sheet being formed of a material that is substantially impermeable to blood. The system may include a leaflet support structure, an inflow end of the leaflet support structure coupled to the atrial sheet. The atrial sheet may define an opening positioned radially outside of the leaflet support structure so that blood flowing around an exterior of the leaflet support structure passes through the opening.

Abstract: A prosthetic tricuspid heart valve system includes a collapsible anchor frame and a collapsible prosthetic heart valve. The anchor includes a support structure having a waisted central portion, and atrial and ventricular flared portions sized to clamp a native valve annulus. Atrial and ventricular sheets are coupled to the atrial and ventricular flared portions, and each include a central aperture. A generally cylindrical fabric valve-receiving member has an inflow end coupled to the atrial sheet and an outflow end coupled to the ventricular sheet to provide a conduit through the valve-receiving member between the atrial and ventricular sheet. The prosthetic heart valve may include a stent and a plurality of prosthetic leaflets, the prosthetic heart valve configured to be expanded into and received within the valve-receiving member of the anchor frame.

Abstract: The present disclosure provides replacement heart valves that include an outer frame, an inner frame, and arms extending therebetween. The outer frame and inner frame may be formed by a plurality of cells, such as diamond shaped cells. The arms may extend from an apex of a diamond shaped cell on the inner frame and be fastened to an apex where adjacent cells of the outer frame adjoin. The arms may include one or more bends. For example, the arms may extend in a first direction for a predefined length, have a bend point, and then extend in a second direction opposite the first. The arms may isolate the inner frame from the outer frame such that forces exerted on the outer frame are absorbed by the arms and do not deform the inner frame.

Abstract: A collapsible and expandable prosthetic atrioventricular valve may include an outer stent, an inner stent, and a plurality of prosthetic leaflets mounted within the inner stent. The outer stent may have an atrial disc, a ventricular disc, and a plurality of posts coupling the atrial disc to the ventricular disc. A plurality of connectors may extend between the inner stent and the outer stent to couple the inner stent to the outer stent. The outer stent may be devoid of metal in a space circumferentially extending between adjacent ones of the plurality of posts. The space may extending approximately one half, approximately one third, or approximately one fourth of a circumference of the outer stent.