Patents by Inventor Grazia Cafeo

Grazia Cafeo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calixpyrrole-based antitumor compounds
    Patent number: 10799480
    Abstract: Calixpyrrole-based antitumor compounds such as compounds of Formula IX: are described, which can be derivatized to obtain their passive transport on tumor masses through the Enhanced Permeation and Retention, EPR, effect of the neoplastic vasculature. The conjugation of the above-mentioned compounds with peptides/antibodies is further described, for their possible active transport on tumor cells.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: October 13, 2020
    Assignee: Giam Pharma International SARL.
    Inventors: Franz Heinrich Kohnke, Alberto Izzotti, Camillo Rosano, Grazia Cafeo
  • CALIXPYRROLE-BASED ANTITUMOR COMPOUNDS
    Publication number: 20190224167
    Abstract: Calixpyrrole-based antitumor compounds are described, which can be derivatized to obtain their passive transport on tumor masses through the Enhanced Permeation and Retention, EPR, effect of the neoplastic vasculature. The conjugation of the above mentioned compounds with peptides/antibodies is further described, for their possible active transport on tumor cells.
    Type: Application
    Filed: September 26, 2017
    Publication date: July 25, 2019
    Inventors: Franz Heinrich Kohnke, Alber Izzotti, Camillo Rosano, Grazia Cafeo