Patents by Inventor Grazia Chiellini

Grazia Chiellini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VITAMIN D ANALOG - RAK, METHODS AND USES THEREOF
    Publication number: 20070191317
    Abstract: Compounds of formula IA or IB are provided where X1, X2 and X3 are independently selected from H or hydroxy protecting groups and R1 is selected from straight or branched chain alkyl groups having from 1 to 8 carbon atoms; straight or branched chain alkenyl groups having from 2 to 8 carbon atoms; straight or branched chain hydroxy-substituted alkyl groups having from 1 to 8 carbon atoms; straight and branched chain hydroxy-substituted alkenyl groups having from 2 to 8 carbon atoms. Such compounds are used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
    Type: Application
    Filed: January 30, 2007
    Publication date: August 16, 2007
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Hector F. DELUCA, Grazia CHIELLINI, Pawel GRZYWACZ, Lori A. PLUM, Margaret CLAGETT-DAME
  • 2-methylene-19-nor-(23S)-25-dehydro-1?-hydroxyvitamin D-26,23-lactone and 2-methylene-19-nor-(23R)-25-dehydro-1?-hydroxyvitamin D-26,23-lactone
    Patent number: 7235680
    Abstract: Compounds of formula 1A and 1B are provided where X1 and X2 are independently selected from H or hydroxy protecting groups.
    Type: Grant
    Filed: March 28, 2006
    Date of Patent: June 26, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Hector F. DeLuca, Lori A. Plum, Margaret Clagett-Dame, Grazia Chiellini, Pawel Grzywacz
  • 2-Methylene-19-nor-(23S)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone and 2-methylene-19-nor-(23R)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone
    Publication number: 20060223782
    Abstract: Compounds of formula 1A and 1B are provided where X1 and X2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological disorders.
    Type: Application
    Filed: March 28, 2006
    Publication date: October 5, 2006
    Inventors: Hector DeLuca, Lori Plum, Margaret Clagett-Dame, Grazia Chiellini, Pawel Grzywacz
  • Method for creating nuclear receptor activity modulating pharmaceuticals
    Publication number: 20040253648
    Abstract: Methods for screening, identifying and/or designing agents that modulate nuclear receptors are provided. These agents contact a site on a nuclear receptor involved in dimer/heterodimer formation, cofactor molecule interactions, and/or folding, which is termed the nuclear receptor dimer/heterodimer regulatory site (DHRS). Methods employing the DHRS are included, along with nuclear receptor:agent complexes and libraries of agents.
    Type: Application
    Filed: December 9, 2003
    Publication date: December 16, 2004
    Applicant: The Regents of the University of California
    Inventors: Robert J. Fletterick, Sabine Borngraeber, John D. Baxter, Thomas S. Scanlan, Grazia Chiellini, Paul Webb
  • Thyroid hormone analogues and methods for their preparation
    Patent number: 6107517
    Abstract: Thyroid hormone analogues are disclosed. Methods of using such analogues and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.
    Type: Grant
    Filed: June 30, 1999
    Date of Patent: August 22, 2000
    Assignee: The Regents of the University of California
    Inventors: Thomas S. Scanlan, Hikari A.I. Yoshihara, Grazia Chiellini, Timothy J. Mitchison
  • Selective thyroid hormone analogs
    Patent number: 5883294
    Abstract: Selective thyroid hormone agonists are disclosed that are highly selective for the TR.beta. subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.
    Type: Grant
    Filed: June 18, 1997
    Date of Patent: March 16, 1999
    Assignee: The Regeants of the University of California
    Inventors: Thomas S. Scanlan, Grazia Chiellini, Hikari Yoshihara, James Apriletti, John D. Baxter, Ralff C. J. Ribeiro