Abstract: The invention concerns a device for localization of stereotactic coordinates by available MRI, CT, PET and angiogram imaging equipment in relation to known art animal stereotactic frames comprised of a pair of bars held in spaced parallel relation to each other by a cross bar that may be fixed to an operating table or the like by means of a fixing device, which connects to the instrument. The instrument may be detached from the stereotactic frame to allow for the imaging procedures. The instrument is made of non-magnetic and radiolucent material allowing for the use of magnetic material and radio-opaque stereotactic frames in combination with available MRI, CT, PET, and angiogram imaging equipment.

Abstract: The invention consists of a device and a method for sectioning of organs and irregular tissue blocks into tissue sections of a predefined thickness and orientation, in one uniform working process. The tissue is embedded into an alginate polymer, which is poured into an embedding container with two opposite arrays of parallel grooves. After hardening, the polymer can be sectioned in slices of a predetermined thickness. This is achieved by razor blade cuts through an array of parallel grooves in the embedding container. Finally, the tissue and alginate polymer can be removed by removing the side of the embedding container resulting in a series of parallel sections of predefined and often equal thickness.