Patents by Inventor Graziella Janssen

Graziella Janssen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminobenzamide derivatives as glycogen synthase kinase 3 beta inhibitors
    Publication number: 20060063789
    Abstract: This invention concerns a compound of formula a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein ring A represents a 6-membered heterocycle; R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; optionally substituted C1-6alkyl; C1-6alkyloxycarbonyl; optionally substituted C1-6alkyloxyC1-6alkylcarbonyl; X is a direct bond or a linker atom or group; Z is O or S; R2 is hydrogen, C1-10alkyl, C2-10alkenyl, C2-10alkynyl, a carbocycle or a heterocycle, each of said groups may optionally be substituted; R3 is hydrogen; hydroxy; halo; optionally substituted C1-6alkyl or C2-6alkenyl or C2-6alkynyl; C1-6alkyloxy; C1-6alkylthio; C1-6alkyloxycarbonyl; C1-6alkylcarbonyloxy; carboxyl; cyano; nitro; amino; mono- or di(C1-6alkyl)amino; polyhaloC1-6alkyl; polyhaloC1-6alkyloxy; polyhaloC1-6alkylthio; R21; R21—C1-6alkyl; R21—O—; R21—S—; R21—C(?O)—; R21—S(?O)p—; R7—S(?O)p—; R7—S(?O)p—NH—; R21—S(?O)p—NH—; R7—C(?O)—; —NHC(?O)H; —C(?O)NHNH2; R7—C(?O)—NH—;
    Type: Application
    Filed: October 29, 2002
    Publication date: March 23, 2006
    Inventors: Eddy Jean Freyne, Peter Antonius, Marc Willems, Werner Johan, Paul Janssen, Paulus Joannes, Jan Heeres, Marc de Jonge, Lucien Koymans, Frederik Daeyaert, Michael Kukla, Hugo Gabriel, Bony Nuydens, Marc Mercken, Donald Ludovici, Herwig Janssen, Paul Maria, Graziella Janssen, Jasmine Werner, Maroussia Janssen, Theodora Arts
  • Amide derivatives as glycogen synthase kinase 3-beta inhibitors
    Publication number: 20050176713
    Abstract: This invention concerns a compound of formula a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein ring A represents a 6-membered heterocycle; R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; optionally substituted C1-6alkyl; C1-6alkyloxycarbonyl; optionally substituted C1-6alkyloxyC1-6alkylcarbonyl; X is a direct bond or a linker atom or group; Z is O or S; R2 is hydrogen, C1-10alkyl, C2-10alkenyl, C2-10alkynyl, a carbocycle or a heterocycle, each of said groups may optionally be substituted; R3 is hydrogen; hydroxy; halo; optionally substituted C1-6alkyl or C2-6alkenyl or C2-6alkynyl; C1-6alkyloxy; C1-6alkylthio; C1-6alkyloxycarbonyl; C1-6alkylcarbonyloxy; carboxyl; cyano; nitro; amino; mono- or di(C1-6alkyl)amino; polyhaloC1-6alkyl; polyhaloC1-6alkyloxy; polyhaloC1-6alkylthio; R21; R21-C1-6alkyl; R21—O—; R21—S—; R21—C(?O)—; R21—S(?O)p—; R7—S(?O)p—; R7—S(?O)p—NH—; R21—S(?O)p—NH—; R7—C(?O)—; —NHC(?O)H; —C(?O)NHNH2; R7—C(?O)—NH—;
    Type: Application
    Filed: October 29, 2002
    Publication date: August 11, 2005
    Inventors: Eddy Jean Freyne, Peter Jacobus Johannes Buijnsters, Marc Willems, Werner Constant Embrechts, Jean Fernand Lacrampe, Paul Adriaan Janssen, Herwig Josephus Janssen, Paul Janssen, Graziella Janssen, Jasmine Janssen, Maroussia Godelieve Janssen, Theodora Joanna Arts, Paulus Lewi, Jan Heeres, Marc de Jonge, Lucien Maria Koymans, Frederik Frans Daeyaert, Rony Nuydens, Marc Mercken