Patents by Inventor Greg BROOKE

Greg BROOKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic nucleic acid molecules
    Patent number: 12378559
    Abstract: Certain aspects of the present invention relate to methods and reagents for the treatment of prostate cancer. Also included in the present invention is an enzymatic nucleic acid molecule (“DNAzyme”) comprising a catalytic core and two specific binding arms complementary to a nucleic acid sequence comprised in an Androgen Receptor mRNA molecule. Also included are compositions comprising the enzymatic nucleic acid molecules and methods of treating disorders such as prostate cancer comprising use of such nucleic acid molecules.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: August 5, 2025
    Assignee: UNIVERSITY OF ESSEX ENTERPRISES LIMITED
    Inventors: Greg Brooke, Antonio Marco Castillo, Angela Pine
  • DNAZYME DESIGN
    Publication number: 20240274227
    Abstract: A method for providing at least one DNAzyme for performing a predetermined function on a target string and a method for training computer implemented instructions executable on a processor for providing at least one DNAzyme for performing a predetermined function on a target string are disclosed.
    Type: Application
    Filed: May 13, 2022
    Publication date: August 15, 2024
    Inventors: Antonio MARCO CASTILLO, Greg BROOKE, Angela PINE
  • ENZYMATIC NUCLEIC ACID MOLECULES
    Publication number: 20210395753
    Abstract: Certain aspects of the present invention relate to methods and reagents for the treatment of prostate cancer. Also included in the present invention is an enzymatic nucleic acid molecule (“DNAzyme”) comprising a catalytic core and two specific binding arms complementary to a nucleic acid sequence comprised in an Androgen Receptor mRNA molecule. Also included are compositions comprising the enzymatic nucleic acid molecules and methods of treating disorders such as prostate cancer comprising use of such nucleic acid molecules.
    Type: Application
    Filed: October 31, 2019
    Publication date: December 23, 2021
    Inventors: Greg BROOKE, Antonio MARCO, Angela PINE