Patents by Inventor Greg Cope

Greg Cope has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulation of target protein activity through modifier proteins
    Patent number: 6846663
    Abstract: The present invention is based on the discovery that a polypeptide containing the JAB subunit or the JAM domain has peptidase activity, e.g., isopeptidase activity. The present invention provides polypeptides and crystalline polypeptides containing the JAM domain and methods of using such polypeptides to screen for agents capable of affecting the peptidase activity of the polypeptides. The present invention also provides methods of using the JAM domain for rational drug design or identifying agents capable of affecting the peptidase activity of the JAM domain.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: January 25, 2005
    Assignee: California Institute of Technology
    Inventors: Svetlana A. Lyapina, Rati Verma, Raymond Deshaies, Greg Cope
  • Regulation of target protein activity through modifier proteins
    Publication number: 20040259193
    Abstract: The present invention is based on the discovery that a polypeptide containing the JAB subunit or the JAM domain has peptidase activity, e.g., isopeptidase activity. The present invention provides polypeptides and crystalline polypeptides containing the JAM domain and methods of using such polypeptides to screen for agents capable of affecting the peptidase activity of the polypeptides. The present invention also provides methods of using the JAM domain for rational drug design or identifying agents capable of affecting the peptidase activity of the JAM domain.
    Type: Application
    Filed: November 25, 2003
    Publication date: December 23, 2004
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Svetlana A. Lyapina, Rati Verma, Raymond Deshaies, Greg Cope
  • Regulation of target protein activity through modifier proteins
    Publication number: 20020156012
    Abstract: The present invention is based on the discovery that a polypeptide containing the JAB subunit or the JAM domain has peptidase activity, e.g., isopeptidase activity. The present invention provides polypeptides and crystalline polypeptides containing the JAM domain and methods of using such polypeptides to screen for agents capable of affecting the peptidase activity of the polypeptides. The present invention also provides methods of using the JAM domain for rational drug design or identifying agents capable of affecting the peptidase activity of the JAM domain.
    Type: Application
    Filed: January 14, 2002
    Publication date: October 24, 2002
    Inventors: Svetlana A. Lyapina, Rati Verma, Raymond Deshaies, Greg Cope