Abstract: An apparatus, system or device and methods for applying one or more stimuli to an implantation, occlusive device, or embolization are described. The implantation can include a polymer or polymer composition such as a hydrogel and can be used for sterilizing a subject in need of contraception by occluding the vas deferens, fallopian tube(s), or uterus, but can also be used to occlude, in whole or part, any other body ducts or organs. The one or more stimuli can modify the occlusion so that is removed from the body lumen in situ, there by reversing the contraception or other effects of the occlusion.

Abstract: Described are methods for reversible occlusion of a body lumen by way of degradation as a result of exposure to one or more stimuli such as light. The methods include administering one or more substance(s) into a body lumen of a subject and forming a stimuli-responsive polymer mass in the body lumen from the one or more substance(s). The mass is sufficient to occlude the body lumen in a manner that prevents transport of at least one material through the body lumen and is susceptible to on-command reversal in the body lumen upon exposure to one or more stimuli. The methods include administering one or more stimuli to a polymer mass in a body lumen for a time and intensity to cause the reverse the polymer mass. The methods are particular useful for applications in which it is desirable to temporarily occlude a body lumen, such as male and female contraception.