Patents by Inventor Greg Harrowe

Greg Harrowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genes Differentially Expressed in Breast Cancer
    Publication number: 20130196314
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Application
    Filed: August 2, 2012
    Publication date: August 1, 2013
    Applicant: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang
  • Genes differentially expressed in breast cancer
    Patent number: 8236928
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: August 7, 2012
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang
  • HX2004-6 polypeptide expressed in cancerous cells
    Patent number: 7867731
    Abstract: The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: January 11, 2011
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Christoph Reinhard, Anne Bennett Jefferson, Vivien W. Chan, Joerg Kaufmann, Hong Xin, Giulia C. Kennedy, Greg Harrowe, Hamiduddin Khoja, Venkatakrishna Shyamala
  • Genes differentially expressed in breast cancer
    Patent number: 7605246
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Grant
    Filed: January 9, 2001
    Date of Patent: October 20, 2009
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang
  • Genes differentially expressed in breast cancer
    Publication number: 20060216748
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Application
    Filed: June 8, 2006
    Publication date: September 28, 2006
    Applicant: Chiron Corporation
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang
  • Genes differentially expressed in breast cancer
    Patent number: 7081517
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: July 25, 2006
    Assignee: Chiron Corporation
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang
  • Gene products differentially expressed in cancerous cells and their methods of use V
    Publication number: 20050130926
    Abstract: The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
    Type: Application
    Filed: October 28, 2004
    Publication date: June 16, 2005
    Inventors: Christoph Reinhard, Anne Jefferson, Vivien Chan, Joerg Kaufmann, Hong Xin, Giulia Kennedy, Greg Harrowe, Hamiduddin Khoja, Venkatakrishna Shyamala
  • Methods for determining metastatic potential of breast cancer cells by detecting GSEF gene product expression
    Patent number: 6566063
    Abstract: The invention features methods for detection of metastatic and potentially metastatic cancerous cells by detection of expression of a gland-specific Ets transcription factor (GSEF) sequence, which encodes an Ets-domain containing protein. The invention also features methods and compositions for modulation of the polypeptide and/or gene activity for prophylactic and therapeutic purposes, such as inhibition of progression of a cell to a metastatic cancerous cell.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: May 20, 2003
    Assignee: Chiron Corporation
    Inventors: Joerg Kaufmann, Hong Xin, Greg Harrowe
  • Genes differentially expressed in breast cancer
    Publication number: 20030017517
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Application
    Filed: July 18, 2002
    Publication date: January 23, 2003
    Applicant: Chiron Corporation
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang
  • Genes differentially expressed in breast cancer
    Publication number: 20020004239
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Application
    Filed: January 9, 2001
    Publication date: January 10, 2002
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang