Patents by Inventor Greg Hinkle

Greg Hinkle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS DIRECTED TO TREATING LIVER FIBROSIS
    Publication number: 20190016751
    Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the COL1A1, TGF-?, and SMAD2/3 genes, and methods of using such dsRNA compositions to inhibit expression of COL1A1, TGF-?, and SMAD2/3.
    Type: Application
    Filed: February 26, 2018
    Publication date: January 17, 2019
    Applicant: Alnylam Pharmaceuticals, Inc.
    Inventors: Greg Hinkle, Victor Kotelianski, Brian Bettencourt, Alfica Sehgal, Tatiana Novobrantseva
  • Compositions and methods directed to treating liver fibrosis
    Patent number: 9944671
    Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the COL1A1, TGF-?, and SMAD2/3 genes, and methods of using such dsRNA compositions to inhibit expression of COL1A1, TGF-?, and SMAD2/3.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: April 17, 2018
    Assignee: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: Greg Hinkle, Victor Kotelianski, Brian Bettencourt, Alfica Sehgal, Tatiana Novobrantseva
  • Socially augmented browsing of a website
    Patent number: 9871877
    Abstract: A computer system enables users of an Internet application (such as a web site or a mobile application) to specify that they wish to be members of one or more groups. The computer system provides the user with information about activities performed by other users who are members of the same group as the user. For example, the computer system may inform a user of the web pages currently being viewed and/or recently viewed by other users who are members of the same group(s) as the user. Examples of other information that the computer system may inform the user about include amount of time spent by other users in the same group on particular web pages, content shared by those users, and products purchased by those users. Groups may be created by the users themselves and/or by the administrators of the Internet application.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: January 16, 2018
    Assignee: Evergage, Inc.
    Inventors: Karl Wirth, Greg Hinkle, Chris Phelan
  • Socially Augmented Browsing of a Website
    Publication number: 20160044119
    Abstract: A computer system enables users of an Internet application (such as a web site or a mobile application) to specify that they wish to be members of one or more groups. The computer system provides the user with information about activities performed by other users who are members of the same group as the user. For example, the computer system may inform a user of the web pages currently being viewed and/or recently viewed by other users who are members of the same group(s) as the user. Examples of other information that the computer system may inform the user about include amount of time spent by other users in the same group on particular web pages, content shared by those users, and products purchased by those users. Groups may be created by the users themselves and/or by the administrators of the Internet application.
    Type: Application
    Filed: August 7, 2015
    Publication date: February 11, 2016
    Applicant: Evergage, Inc.
    Inventors: Karl Wirth, Greg Hinkle, Chris Phelan
  • GNAQ targeted dsRNA compositions and methods for inhibiting expression
    Patent number: 8889644
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a G-alpha q subunit (GNAQ) of a heterotrimeric G gene, and methods of using the dsRNA to inhibit expression of GNAQ.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: November 18, 2014
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: Jared Gollob, Greg Hinkle, Ivanka Toudjarska, David Bumcrot
  • COMPOSITIONS AND METHODS DIRECTED TO TREATING LIVER FIBROSIS
    Publication number: 20130158097
    Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the COL1A1, TGF-?, and SMAD2/3 genes, and methods of using such dsRNA compositions to inhibit expression of COL1A1, TGF-?, and SMAD2/3.
    Type: Application
    Filed: June 2, 2011
    Publication date: June 20, 2013
    Applicant: Alnylam Pharmaceuticals, Inc.
    Inventors: Greg Hinkle, Victor Kotelianski, Brian Bettencourt, Alfica Sehgal, Tatiana Novobrantseva
  • GNAQ TARGETED dsRNA COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION
    Publication number: 20130012570
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a G-alpha q subunit (GNAQ) of a heterotrimeric G gene, and methods of using the dsRNA to inhibit expression of GNAQ.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Inventors: Jared Gollob, Greg Hinkle, Ivanka Toudjarska, David Bumcrot