Abstract: A peripheral device for regulating neural correlates of arousal and emotion regulation to be worn or held against the body is disclosed. The device can be triggered by either physiological signs or manual intervention and produces cutaneous signals such as vibration or electricity using novel combinations of physiologically reactive frequencies without effort on the part of the user. One embodiment includes combining sensors that measure changes in physiological signals of stress such as speech rate and pitch, galvanic skin response, or heart rate variability, and, using a machine learning algorithm on personalized data, can determine whether these changes are likely to benefit from regulation. If they are outside an idiosyncratic predetermined range, the device produces stimulation and the person will feel regulated if they are touching/wearing the device, or can choose to use the device if it is not currently being touched or worn.

Abstract: An improved method of treating depression in a person can be generally said to include applying to a body area of the person a therapeutic stimulation device having a tactile transducer that is positioned proximate the body area, and emitting with the tactile transducer a vibrational output toward the body area. A therapeutic stimulation device and a non-transitory machine-readable storage medium are also disclosed.

Abstract: A peripheral device for regulating neural correlates of arousal and emotion regulation to be worn or held against the body is disclosed. The device can be triggered by either physiological signs or manual intervention and produces cutaneous signals such as vibration or electricity using novel combinations of physiologically reactive frequencies without effort on the part of the user. One embodiment includes combining sensors that measure changes in physiological signals of stress such as speech rate and pitch, galvanic skin response, or heart rate variability, and, using a machine learning algorithm on personalized data, can determine whether these changes are likely to benefit from regulation. If they are outside an idiosyncratic predetermined range, the device produces stimulation and the person will feel regulated if they are touching/wearing the device, or can choose to use the device if it is not currently being touched or worn.