Abstract: A power converter is provided that includes a power inverter, a rectifier circuit and an isolation transformer circuit. The power inverter is to convert a direct current (DC) input to an alternating current (AC) output, the power inverter including N bridge circuits connected in parallel, where N>1. The rectifier circuit is to convert the AC output to a DC output, the rectifier circuit including N+1 series diode pairs connected in parallel. The isolation transformer circuit is coupled to and between the power inverter and the rectifier circuit to transfer the AC output from the power inverter to the rectifier circuit, the isolation transformer circuit including N transformers. Respective ones of the N transformers are coupled to one of the N bridge circuits and two of the N+1 series diode pairs.

Abstract: This invention relates to an engineered leader-independent heterocyclase (also known as a cyclodehydratase) comprising a defined cyanobactin leader sequence which drives the efficient conversion of heterocyclisable amino acids, such as Ser, Thr and Cys, within a peptide substrate lacking a leader sequence into heterocycles produce a homogenous heterocycle-containing product. This may be useful in biotechnology and chemical synthesis.

Abstract: This invention relates to an engineered leader-independent heterocyclase (also known as a cyclodehydratase) comprising a defined cyanobactin leader sequence which drives the efficient conversion of heterocyclisable amino acids, such as Ser, Thr and Cys, within a peptide substrate lacking a leader sequence into heterocycles produce a homogenous heterocycle-containing product. This may be useful in biotechnology and chemical synthesis.