Abstract: A catheter assembly is provided. The catheter assembly includes a catheter including at least one lesion generating electrode, the at least one lesion generating electrode configured to be positioned within a patient, and at least one return array configured to be positioned within the patient and remote from the at least one lesion generating electrode, the at least one return array including at least one return electrode, wherein the catheter assembly is configured to apply energy between i) the at least one lesion generating electrode and ii) a return patch and the at least one return electrode to generate lesions proximate the at least one lesion generating electrode.

Abstract: A treadmill for backward walking is disclosed. The treadmill may include a static frame and dynamic platform pivotally mounted to the static frame. A C-shaped support handle includes side portions that may be grasped or otherwise used by a user to stabilize their position, and a cross member against which the user may lean, e.g. with the user's hips or back. A user may press against a treadmill belt with the user's feet, against resistance from a brake, to move the treadmill belt away from the user's body.

Abstract: Materials, methods and techniques relate to steel alloys. In some instances, steel alloys can include chromium, molybdenum, vanadium, copper, nickel, manganese, niobium, aluminum, and iron. In some instances, exemplary steel alloys are subjected to solution carburizing, tempering, and/or plasma nitriding. Exemplary steel alloys are typically precipitation strengthened carburizable and nitridable steel alloys.

Abstract: A treadmill for backward walking is disclosed. The treadmill may include a static frame and dynamic platform pivotally mounted to the static frame. A C-shaped support handle includes side portions that may be grasped or otherwise used by a user to stabilize their position, and a cross member against which the user may lean, e.g. with the user's hips or back. A user may press against a treadmill belt with the user's feet, against resistance from a brake, to move the treadmill belt away from the user's body.

Abstract: Exemplary alloys may comprise, by weight percentage, 13.25% to 14.75% chromium; 4.5% to 5.5% nickel; 0.11% to 0.17% carbon; 0.01% to 0.31% titanium; and the balance of weight percent comprising iron and incidental elements and impurities. Exemplary methods may include conducting additive manufacturing with an atomized alloy powder to generate a manufactured article, where the atomized alloy powder may comprise, by weight percentage, 13.25% to 14.75% chromium; 4.5% to 5.5% nickel; 0.11% to 0.17% carbon; 0.01% to 0.31% titanium; and the balance of weight percent comprising iron and incidental elements and impurities.

Abstract: The present disclosure provides electroporation catheters that are capable of forming a loop, generally a circular loop, an oval loop, or like in shape, located on the distal end portion of a catheter shaft within the vasculature of an individual. The electroporation catheters of the present disclosure may be delivered into the vasculature of the individual in a straight conformation and allow for the formation of the loop once positioned in the desired location. Some embodiments of the present disclosure include an electroporation catheter that includes a loop member pull wire in a spiral or helical configuration on an inside surface of the distal end portion of the catheter shaft.

Abstract: A method of navigating a catheter to a target location in an anatomical structure of a patient includes inserting a portion of a catheter into the patient. The catheter includes an elongate shaft having a proximal and a distal end, and a loop subassembly coupled to the distal end. The loop subassembly includes a loop coupled to the distal end and positioned parallel to the elongate shaft, and electrodes disposed on the loop. The method includes positioning one of a portion of the loop subassembly and a portion of the distal end of the elongate shaft in contact with a surface of the anatomical structure a distance from the target location, and translating the loop subassembly toward the target location with the one of the portion of the loop subassembly and the portion of the distal end of the elongate shaft in contact with the surface of the anatomical structure.

Abstract: A catheter assembly is provided. The catheter assembly includes a tip electrode array including at least one tip electrode, the tip electrode array located at a distal end of the catheter assembly, and a mini electrode array including a plurality of mini electrodes, the mini electrode array positioned proximal of the tip electrode array, wherein each of the at least one tip electrode and each of the plurality of mini electrodes are configured to be activated independent of one another for mapping applications, and wherein at least some of the at least one tip electrode and the plurality of mini electrodes are configured to be activated in unison for ablation applications.

Abstract: A catheter includes a shaft including a proximal end and a distal end, an electrical conductor coupled to the catheter, and an electrode coupled to the electrical conductor. The electrode includes at least one recessed portion, and an impedance reduction layer disposed in the at least one recessed portion. The impedance reduction layer has a thickness less than a depth of the recessed portion.

Abstract: The present disclosure provides electroporation catheters that are capable of forming a loop, generally a circular loop, an oval loop, or like in shape, located on the distal end portion of a catheter shaft within the vasculature of an individual. The electroporation catheters of the present disclosure may be delivered into the vasculature of the individual in a straight conformation and allow for the formation of the loop once positioned in the desired location. Some embodiments of the present disclosure include an electroporation catheter that includes a loop member pull wire in a spiral or helical configuration on an inside surface of the distal end portion of the catheter shaft.

Abstract: A treadmill for backward walking is disclosed. The treadmill may include a static frame and dynamic platform pivotally mounted to the static frame. A C-shaped support handle includes side portions that may be grasped or otherwise used by a user to stabilize their position, and a cross member against which the user may lean, e.g. with the user's hips or back. A user may press against a treadmill belt with the user's feet, against resistance from a brake, to move the treadmill belt away from the user's body.

Abstract: Exemplary martensitic steel alloys may be particularly suited for additive manufacturing applications. Exemplary atomized alloy powders usable in additive manufacturing may include carbon, nickel, manganese, chromium, and the balance iron and incidental impurities. Exemplary steel alloys can be molybdenum free.

Abstract: A method of forming a spline for an electrode assembly includes providing a structural member including a first surface and a second surface. The method also includes providing a flexible circuit assembly including a plurality of electrodes and at least one flexible circuit substrate having a contact surface and an outer surface opposite the contact surface. The plurality of electrodes are disposed on the outer surface of the at least one flexible circuit substrate. The method includes positioning the flexible circuit assembly relative to the structural member such that a first set of electrodes is aligned with the first surface and a second set of electrodes is aligned with the second surface. The method also includes coupling the at least one flexible circuit substrate to at least one of the structural member and the at least one flexible circuit substrate.

Abstract: Disclosed herein is a multi-electrode catheter system including an amplifier stage and an amplifier interface. The amplifier stage includes at least a first quantity of amplifier channels. The amplifier interface includes a first interface having at least the first quantity of interface channels. The amplifier channels are respectively electrically coupled to the interface channels The amplifier interface includes a second interface having a second quantity of catheter channels, the second quantity being greater than the first quantity. The catheter channels are configured to be respectively electrically coupled to corresponding electrode leads of a multi-electrode catheter. The amplifier interface includes a switching matrix electrically coupled between the first interface and the second interface. The switching matrix is configured to selectively electrically couple a selected subset of catheter channels to respective interface channels of the first quantity of interface channels.

Abstract: An apparatus for controlling an electroporation catheter is provided. The electroporation catheter includes a distal end, a proximal end, at least one spline extending from the distal end to the proximal end, and a plurality of electrodes arranged on the at least one spline. The apparatus includes a pulse generator coupled to the electroporation catheter, and a computing device coupled to the pulse generator, the computing device operable to control the pulse generator to selectively energize the plurality of electrodes on the electroporation catheter to form an energization pattern.

Abstract: Exemplary alloys may comprise, by weight percentage, 13.25% to 14.75% chromium; 4.5% to 5.5% nickel; 0.11% to 0.17% carbon; 0.01% to 0.31% titanium; and the balance of weight percent comprising iron and incidental elements and impurities. Exemplary methods may include conducting additive manufacturing with an atomized alloy powder to generate a manufactured article, where the atomized alloy powder may comprise, by weight percentage, 13.25% to 14.75% chromium; 4.5% to 5.5% nickel; 0.11% to 0.17% carbon; 0.01% to 0.31% titanium; and the balance of weight percent comprising iron and incidental elements and impurities.

Abstract: Complex concentrated alloys include five or more elements, at least one of which is ruthenium. Example complex concentrated alloys can include nickel and chromium, iron, ruthenium, molybdenum, and/or tungsten. Example complex concentrated alloys have single phase microstructure of face centered cubic (FCC) and can be homogenous. Example complex concentrated alloys can exhibit improved corrosion resistance.

Abstract: A medical device may include a tubular body defining a central longitudinal axis and a lumen, the tubular body including an annular wall having an inner circumferential surface and an outer circumferential surface. The medical device may include a multi-core fiber extending along at least a portion of the length of the tubular body and at least partially disposed in the annular wall thereof. The medical device may include a plurality of single-core fibers extending along at least a portion of the length of the tubular body and defining a central longitudinal axis that is nonparallel to the central longitudinal axis of the tubular body. A medical device may include a multi-core fiber disposed on a top surface of a first layer and extending along at least a portion of the length of the first layer; and a second layer deposited or printed on the first layer.

Abstract: Exemplary martensitic steel alloys may be particularly suited for additive manufacturing applications. Exemplary atomized alloy powders usable in additive manufacturing may include carbon, nickel, manganese, chromium, and the balance iron and incidental impurities. Exemplary steel alloys can be molybdenum free.

Abstract: Materials, methods and techniques relate to steel alloys. In some instances, steel alloys can include chromium, molybdenum, vanadium, copper, nickel, manganese, niobium, aluminum, and iron. In some instances, exemplary steel alloys are subjected to solution carburizing, tempering, and/or plasma nitriding. Exemplary steel alloys are typically precipitation strengthened carburizable and nitridable steel alloys.