Patents by Inventor Greg Petsko

Greg Petsko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
    Publication number: 20250163114
    Abstract: Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.
    Type: Application
    Filed: January 16, 2025
    Publication date: May 22, 2025
    Applicant: Brandeis University
    Inventors: Greg Petsko, Dagmar Ringe, Shulin Ju
  • Methods of reducing FUS/TLS- or TDP-43-mediated neuronal cytotoxicity in amyotrophic lateral sclerosis (ALS) by UPF2
    Patent number: 12275764
    Abstract: Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: April 15, 2025
    Assignee: Brandeis University
    Inventors: Greg Petsko, Dagmar Ringe, Shulin Ju
  • TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
    Publication number: 20230054101
    Abstract: Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.
    Type: Application
    Filed: April 15, 2022
    Publication date: February 23, 2023
    Inventors: Greg Petsko, Dagmar Ringe, Shulin Ju
  • Methods of reducing FUS/TLS- or TDP-43-mediated neuronal cytotoxicity by UPF1
    Patent number: 11332504
    Abstract: Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: May 17, 2022
    Assignee: Brandeis University
    Inventors: Greg Petsko, Dagmar Ringe, Shulin Ju
  • TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
    Publication number: 20200131236
    Abstract: Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.
    Type: Application
    Filed: January 10, 2020
    Publication date: April 30, 2020
    Inventors: Greg Petsko, Dagmar Ringe, Shulin Ju
  • Methods of reducing TDP-43-mediated neuronal cytotoxicity in amyotrophic lateral sclerosis by a UPF1 polypeptide or polynucleotide
    Patent number: 10533038
    Abstract: Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: January 14, 2020
    Assignee: Brandeis University
    Inventors: Greg Petsko, Dagmar Ringe, Shulin Ju