Patents by Inventor Greg Salamo

Greg Salamo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for X-ray induced release from pH sensitive liposomes
    Patent number: 10220000
    Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: March 5, 2019
    Assignees: The Board of Trustees of the University of Arkansas, BioVentures, LLC
    Inventors: Daniel Fologea, Ralph Henry, Greg Salamo, Yuriy Mazur, Michael J. Borrelli
  • Methods and Compositions for X-ray Induced Release from pH Sensitive Liposomes
    Publication number: 20180104188
    Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.
    Type: Application
    Filed: December 19, 2017
    Publication date: April 19, 2018
    Applicant: The Board of Trustees of the University of Arkansas
    Inventors: Daniel Fologea, Ralph Henry, Greg Salamo, Yuriy Mazur, Michael J. Borrelli
  • Methods and compositions for X-ray induced release from pH sensitive liposomes
    Patent number: 9849087
    Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: December 26, 2017
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Daniel Fologea, Ralph Henry, Greg Salamo, Yuriy Mazur, Michael J. Borrelli
  • METHODS AND COMPOSITIONS FOR X-RAY INDUCED RELEASE FROM PH SENSITIVE LIPOSOMES
    Publication number: 20140328905
    Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.
    Type: Application
    Filed: November 8, 2012
    Publication date: November 6, 2014
    Inventors: Daniel Fologea, Ralph Henry, Greg Salamo, Yuriy Mazur, Michael J. Borrelli
  • Method of controlled drug release from a liposome carrier
    Patent number: 8808733
    Abstract: Disclosed are methods and compositions for the controlled release of a drug or agent from a liposome using light or radiation. Also disclosed are compositions comprising liposomes having a lipid layer, wherein the liposomes contain an agent, an enzyme capable of releasing the agent from the liposome, and an enzyme activator sequestered by a molecular cage. In another aspect, methods of delivering an agent to a target in a subject are disclosed.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: August 19, 2014
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Daniel Fologea, Greg Salamo, Ralph Henry, Michael J. Borrelli, Peter M. Corry
  • METHOD OF CONTROLLED DRUG RELEASE FROM A LIPOSOME CARRIER
    Publication number: 20120041357
    Abstract: Disclosed are methods and compositions for the controlled release of a drug or agent from a liposome using light or radiation. Also disclosed are compositions comprising liposomes having a lipid layer, wherein the liposomes contain an agent, an enzyme capable of releasing the agent from the liposome, and an enzyme activator sequestered by a molecular cage. In another aspect, methods of delivering an agent to a target in a subject are disclosed.
    Type: Application
    Filed: March 31, 2010
    Publication date: February 16, 2012
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
    Inventors: Daniel Fologea, Greg Salamo, Ralph Henry, Michael J. Borrelli, Peter M. Corry