Abstract: The present invention provides a safe and effective package for housing a dosage, which is easily opened by a user yet provides a secure and contaminant-free environment for the dosage housed within. The package may include a guided tear condition extending along at least one edge of the package, allowing a user to safely and effectively open the package without risk of compromising the dosage housed therein. In some embodiments, the dosage is a substantially flat dosage, such as a film.

Abstract: The invention relates to single-layer oral disintegrating films having at least two distinct zones, which comprise nicotine and allow for effective buccal (=oral mucosal) absorption thereof.

Abstract: The invention relates to oral disintegrable films, which are mucoadhesive, which completely disintegrate in the mouth of a consumer within 1 to 10 minutes, and which include an alkaline substance and optionally a pharmaceutically active substance.

Abstract: The present invention provides a taste-masked composition containing an active compound. The composition is taste-masked by employing a loaded polymeric matrix which is produced by incorporating or complexing the active compound on a polymeric matrix having ionic functional groups and removing unbound active compounds from the polymeric matrix.

Abstract: The invention relates to pharmaceutical compositions suitable for oral administration in the form of edible films comprising diclofenac.

Abstract: A water soluble film that is disintegrable in the oral cavity to deliver an active agent is provided. The disintegrable film includes at least one water soluble polymer and an active agent. Also provided are methods for preparing the disintegrable oral film and for using the disintegrable film to administer an effective dosage of an active agent into the oral cavity for absorption through the oral mucosa. According to certain embodiments, the disintegrable film includes at least one water soluble polymer and a nicotine active.

Abstract: A method is provided to splice and/or repair films. The method comprises: a) applying a splicing composition to a first water-soluble, orally-ingestible film, a second water-soluble, orally-ingestible film or to both films; b) overlapping the first water-soluble, orally-ingestible film on the second water-soluble, orally-ingestible film to form a splice between the first water-soluble, orally-ingestible film and the second water-soluble, orally-ingestible film; and c) allowing the splice to dry or cure, wherein the splicing composition comprises at least one animal-consumable solvent and, optionally, at least one orally-ingestible polymer.