Patents by Inventor Greg Stahler
Greg Stahler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20200114162Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: September 24, 2019Publication date: April 16, 2020Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Ananya Mitra, Joyce Huang, Dan Andersen, Alexander K. Arrow, David Moore
-
Publication number: 20190391347Abstract: Configurations are described for creating and using separable optical feedthroughs. These are especially useful in their at least semi-hermetic form when integrated with implantable photomedical devices. One embodiment is directed to a system for operatively coupling an optical output from a light source positioned inside of a sealed housing to an external optical fiber, comprising: a first optical fiber disposed adjacent to the light source and configured to receive at least a portion of the optical output; a second optical fiber operatively coupled to the first optical fiber and configured to capture at least a portion of an output from the first optical fiber; a primary seal operatively coupled to the housing between the light source and the second optical fiber that is at least partially transparent; and a secondary seal positioned between the second optical fiber and the environment.Type: ApplicationFiled: September 3, 2019Publication date: December 26, 2019Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, David Angeley, Brian Andrew Ellingwood
-
Publication number: 20190129111Abstract: Configurations are described for creating and using separable optical feedthroughs. These are especially useful in their at least semi-hermetic form when integrated with implantable photomedical devices. One embodiment is directed to a system for operatively coupling an optical output from a light source positioned inside of a sealed housing to an external optical fiber, comprising: a first optical fiber disposed adjacent to the light source and configured to receive at least a portion of the optical output; a second optical fiber operatively coupled to the first optical fiber and configured to capture at least a portion of an output from the first optical fiber; a primary seal operatively coupled to the housing between the light source and the second optical fiber that is at least partially transparent; and a secondary seal positioned between the second optical fiber and the environment.Type: ApplicationFiled: December 27, 2018Publication date: May 2, 2019Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, David Angeley, Brian Andrew Ellingwood
-
Publication number: 20190105507Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: December 11, 2018Publication date: April 11, 2019Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Dan Andersen, Joyce Huang, David C. Lundmark, David Moore
-
Publication number: 20190015677Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: September 18, 2018Publication date: January 17, 2019Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Dan Andersen, Joyce Huang, David C. Lundmark, David Moore
-
Patent number: 10105550Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: GrantFiled: July 31, 2014Date of Patent: October 23, 2018Assignee: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Ananya Mitra, Joyce Huang, Dan Andersen, Alexander Arrow, David Moore
-
Publication number: 20180280716Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: March 28, 2018Publication date: October 4, 2018Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Ananya Mitra, Joyce Huang, Dan Andersen, Alexander K. Arrow, David Moore
-
Publication number: 20180214711Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: March 27, 2018Publication date: August 2, 2018Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Ananya Mitra, Joyce Huang, Dan Andersen, Alexander K. Arrow, David Moore
-
Patent number: 10022552Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: GrantFiled: July 31, 2014Date of Patent: July 17, 2018Assignee: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Ananya Mitra, Joyce Huang, Dan Andersen, Alexander K. Arrow, David Moore
-
Publication number: 20180156994Abstract: Configurations are described for creating and using separable optical feedthroughs. These are especially useful in their at least semi-hermetic form when integrated with implantable photomedical devices. One embodiment is directed to a system for operatively coupling an optical output from a light source positioned inside of a sealed housing to an external optical fiber, comprising: a first optical fiber disposed adjacent to the light source and configured to receive at least a portion of the optical output; a second optical fiber operatively coupled to the first optical fiber and configured to capture at least a portion of an output from the first optical fiber; a primary seal operatively coupled to the housing between the light source and the second optical fiber that is at least partially transparent; and a secondary seal positioned between the second optical fiber and the environment.Type: ApplicationFiled: January 30, 2018Publication date: June 7, 2018Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, David Angeley, Brian Andrew Ellingwood
-
Publication number: 20180140862Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: December 21, 2017Publication date: May 24, 2018Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Dan Andersen, Joyce Huang, David C. Lundmark, David Moore
-
Publication number: 20180133501Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: November 3, 2017Publication date: May 17, 2018Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Dan Andersen, Joyce Huang, David C. Lundmark, David Moore
-
Patent number: 9918681Abstract: The invention comprises a virtual window system that creates a visual coherency between the image of the patient and his or her anatomy and the patient by aligning the image of the patient anatomy on the display to the patient and presenting the image to the user that feels as if the user is looking directly into the patient through the display. The invention is designed to also display medical devices, such as a minimally invasive tool. The system substantially unifies the coordinate systems of the patient, the medical device, the display, and the physician's hands. The invention creates a visual coherency between the motion of the medical device in the image and the motion of the physician's hands manipulating the device. This invention also creates a visual coherency between the motion of the image in the display and of that display.Type: GrantFiled: September 14, 2012Date of Patent: March 20, 2018Assignee: Auris Surgical Robotics, Inc.Inventors: Dan Wallace, Greg Stahler, Jaime Waydo, Aaron Grogan
-
Publication number: 20170239488Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: March 28, 2017Publication date: August 24, 2017Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Dan Andersen, Joyce Huang, David C. Lundmark, David Moore
-
Publication number: 20170225008Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.Type: ApplicationFiled: March 29, 2017Publication date: August 10, 2017Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, Dan Andersen, Joyce Huang, David C. Lundmark, David Moore
-
Publication number: 20170205595Abstract: Configurations are described for creating and using separable optical feedthroughs. These are especially useful in their at least semi-hermetic form when integrated with implantable photomedical devices. One embodiment is directed to a system for operatively coupling an optical output from a light source positioned inside of a sealed housing to an external optical fiber, comprising: a first optical fiber disposed adjacent to the light source and configured to receive at least a portion of the optical output; a second optical fiber operatively coupled to the first optical fiber and configured to capture at least a portion of an output from the first optical fiber; a primary seal operatively coupled to the housing between the light source and the second optical fiber that is at least partially transparent; and a secondary seal positioned between the second optical fiber and the environment.Type: ApplicationFiled: April 3, 2017Publication date: July 20, 2017Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, David Angeley, Brian Andrew Ellingwood
-
Publication number: 20170182191Abstract: One embodiment is directed to a method for controllably managing pain in the afferent nervous system of a patient having a targeted tissue structure that has been genetically modified to have light sensitive protein, comprising: providing a light delivery element configured to direct radiation to at least a portion of a targeted tissue structure, a light source configured to provide light to the light delivery element, and a controller operatively coupled to light source, wherein the targeted tissue structure comprises a sensory neuron of the patient; and automatically operating the controller to illuminate the targeted tissue structure with radiation such that a membrane potential of cells comprising the targeted tissue structure is modulated at least in part due to exposure of the light sensitive protein to the radiation.Type: ApplicationFiled: July 29, 2015Publication date: June 29, 2017Applicant: Circuit Therapeutics, Inc.Inventors: Christopher L. Towne, Michael Kaplitt, Scott Delp, Karl Deisseroth, David Angeley, Greg Stahler, Dan Andersen, David C. Lundmark
-
Patent number: 9645332Abstract: Configurations are described for creating and using separable optical feedthroughs. These are especially useful in their at least semi-hermetic form when integrated with implantable photomedical devices. One embodiment is directed to a system for operatively coupling an optical output from a light source positioned inside of a sealed housing to an external optical fiber, comprising: a first optical fiber disposed adjacent to the light source and configured to receive at least a portion of the optical output; a second optical fiber operatively coupled to the first optical fiber and configured to capture at least a portion of an output from the first optical fiber; a primary seal operatively coupled to the housing between the light source and the second optical fiber that is at least partially transparent; and a secondary seal positioned between the second optical fiber and the environment.Type: GrantFiled: July 29, 2015Date of Patent: May 9, 2017Assignee: Circuit Therapeutics, Inc.Inventors: Greg Stahler, David Angeley, Brian Andrew Ellin
-
Publication number: 20160296681Abstract: Methods and apparatus are provided for measuring one or more aspects of breast milk expression. A sensing adaptor comprises a housing having a first end, a second end, and a central channel defined therethrough. The first coupling mechanism is disposed adjacent the first end, and configured to removably couple to a pumping device. The second coupling mechanism is disposed adjacent the second end, and configured to removably couple to a collection vessel receiving the expressed breast milk from the pumping device. The sensing adaptor further comprises a sensor coupled to the housing, the sensor configured to measure one or more aspects of the expressed breast milk as the expressed breast milk enters the collection vessel through the central channel from the pumping device.Type: ApplicationFiled: April 8, 2016Publication date: October 13, 2016Inventors: Nathaniel Gaskin, Jeffery B. Alvarez, Alex Goldenberg, Greg Stahler
-
Publication number: 20160091680Abstract: Configurations are described for creating and using separable optical feedthroughs. These are especially useful in their at least semi-hermetic form when integrated with implantable photomedical devices. One embodiment is directed to a system for operatively coupling an optical output from a light source positioned inside of a sealed housing to an external optical fiber, comprising: a first optical fiber disposed adjacent to the light source and configured to receive at least a portion of the optical output; a second optical fiber operatively coupled to the first optical fiber and configured to capture at least a portion of an output from the first optical fiber; a primary seal operatively coupled to the housing between the light source and the second optical fiber that is at least partially transparent; and a secondary seal positioned between the second optical fiber and the environment.Type: ApplicationFiled: July 29, 2015Publication date: March 31, 2016Applicant: Circuit Therapeutics, Inc.Inventors: Greg Stahler, David Angeley, Brian Andrew Ellin