Patents by Inventor Greg Thiessen

Greg Thiessen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DP04 polymerase variants
    Patent number: 11708566
    Abstract: Recombinant DP04-type DNA polymerase variants with amino acid substitutions that confer modified properties upon the polymerase for improved single molecule sequencing applications are provided. Such properties may include enhanced binding and incorporation of bulky nucleotide analog substrates into daughter strands and the like. Also provided are compositions comprising such DP04 variants and nucleotide analogs, as well as nucleic acids which encode the polymerases with the aforementioned phenotypes.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: July 25, 2023
    Assignee: Stratos Genomics, Inc.
    Inventors: Mark Stamatios Kokoris, Marc Prindle, Jack Chase, Robert Busam, Michael Kovarik, Salka Keller, Megan Murt, Greg Thiessen
  • METHODS, COMPOSITIONS, AND DEVICES FOR SOLID-STATE SYNTEHSIS OF EXPANDABLE POLYMERS FO RUSE IN SINGLE MOLECULE SEQUENCINGS
    Publication number: 20220042075
    Abstract: Methods, compositions and devices for single molecule sequencing are provided, particularly for solid-state synthesis and processing of expandable polymers (e.g., Xpandomers), as well as methods and compositions for producing new expandable polymer constructs that provide more accurate sequence information when passed through a nanopore sensor.
    Type: Application
    Filed: August 17, 2021
    Publication date: February 10, 2022
    Inventors: Lacey Merrill, Marc Prindle, Samantha Vellucci, Jagadeeswaran Chandrasekar, Mark Stamatios Kokoris, Gerson Aguirre, John Tabone, Robert N. McRuer, Michael Lee, Matthew Corning, Greg Thiessen, Salka Keller Barrett, Christian Berrios, Aaron Jacobs, Taylor Lehmann
  • DP04 POLYMERASE VARIANTS
    Publication number: 20210108183
    Abstract: Recombinant DP04-type DNA polymerase variants with amino acid substitutions that confer modified properties upon the polymerase for improved single molecule sequencing applications are provided. Such properties may include enhanced binding and incorporation of bulky nucleotide analog substrates into daughter strands and the like. Also provided are compositions comprising such DP04 variants and nucleotide analogs, as well as nucleic acids which encode the polymerases with the aforementioned phenotypes.
    Type: Application
    Filed: May 3, 2018
    Publication date: April 15, 2021
    Inventors: Mark Stamatios Kokoris, Marc Prindle, Jack Chase, Robert Busam, Michael Kovarik, Salka Keller, Megan Murt, Greg Thiessen