Patents by Inventor Greg Verdine

Greg Verdine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Building blocks for stapled peptides
    Patent number: 11091427
    Abstract: This invention relates to a method for producing an alkenyl 1-aminocyclopropane-1-carboxylic acid of Formula I wherein R1 is a protecting group, n is an integer between 1 and 10, and A and B are chiral centres such that when A is S, B is R and when A is R, B is S. The method comprises a stereoselective formation of the cyclopropane moiety by cycloaddition onto a double bond, in a molecule comprising a chiral template, Formula lc. Further provided is the use of Formula I in the production of stapled peptides.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: August 17, 2021
    Assignee: Agency for Science, Technology and Research
    Inventors: Tsz Ying Yuen, Charles William Johannes, Greg Verdine