Patents by Inventor Gregor Adams

Gregor Adams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8802104
    Abstract: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: August 12, 2014
    Assignee: The General Hospital Corporation
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry M. Kronenberg
  • Patent number: 8309095
    Abstract: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: November 13, 2012
    Assignee: The General Hospital Corporation
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry M. Kronenberg
  • Publication number: 20110224142
    Abstract: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
    Type: Application
    Filed: April 29, 2011
    Publication date: September 15, 2011
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: DAVID T. SCADDEN, LAURA M. CALVI, GREGOR ADAMS, HENRY M. KRONENBERG
  • Patent number: 7943136
    Abstract: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: May 17, 2011
    Assignee: The General Hospital Corporation
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry M. Kronenberg
  • Patent number: 7776334
    Abstract: The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: August 17, 2010
    Assignee: The General Hospital Corporation
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry M. Kronenberg
  • Publication number: 20100113360
    Abstract: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
    Type: Application
    Filed: November 18, 2009
    Publication date: May 6, 2010
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry Kronenberg
  • Patent number: 7635477
    Abstract: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: December 22, 2009
    Assignee: The General Hospital Corporation
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry Kronenberg
  • Publication number: 20090092625
    Abstract: The invention relates to methods for manipulating hematopoietic progenitor cells and related products In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function.
    Type: Application
    Filed: August 28, 2008
    Publication date: April 9, 2009
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry Kronenberg
  • Patent number: 7429383
    Abstract: The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: September 30, 2008
    Assignee: The General Hospital Corporation
    Inventors: David T. Scadden, Laura M. Calvi, Gregor Adams, Henry Kronenberg
  • Publication number: 20080112933
    Abstract: The present invention provides methods for increasing engraftment of stem cells in a subject by treating the cells with a G?s activator. The invention further provides methods for identifying G?s activators for use in increasing engraftment of stem cells in a subject.
    Type: Application
    Filed: November 7, 2005
    Publication date: May 15, 2008
    Inventors: David T. Scadden, Henry M. Kronenberg, Gregor Adams
  • Publication number: 20070281889
    Abstract: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
    Type: Application
    Filed: November 8, 2005
    Publication date: December 6, 2007
    Inventors: David Scadden, Laura Calvi, Gregor Adams, Henry Kronenberg
  • Publication number: 20060257376
    Abstract: The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function.
    Type: Application
    Filed: July 25, 2003
    Publication date: November 16, 2006
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: David Scadden, Laura Calvi, Gregor Adams, Henry Kronenberg
  • Publication number: 20040005661
    Abstract: The invention relates to a mitogen obtainable from a human tumour cell line, such as from HT1080 cells.
    Type: Application
    Filed: July 8, 2003
    Publication date: January 8, 2004
    Inventors: Stephen L. Minger, Gregor Adams, Paul Francis, Myra Mcclure