Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.

Abstract: A phantom for calibration and quality assurance of an MR tomograph that comprises a phantom body with measuring aids and an intermediate bottom in at least four planes. The first plane contains only measuring fluid. The second plane contains wedge-shaped elements. The third plane contains marks of known distance. The fourth plane contains comb-shaped elements. The measuring aids of the second plane are arranged on one side of the intermediate bottom and those of the fourth plane on the other side. The marks of the third plane are arranged in the intermediate bottom. This arrangement enables reliable calibration of the MR tomograph in a few steps with only this phantom.

Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.

Abstract: The present disclosure is concerned with the technical field of marking objects with optically readable codes and reading out (decoding) the codes. Subjects of the present disclosure are a method, a system and a computer program product for decoding optically readable codes introduced in surfaces of objects.

Abstract: Herein is reported a method for determining the concentration of a therapeutic antibody in a tissue of an experimental animal to whom the therapeutic antibody had been administered, wherein the interference from residual blood in a tissue sample of the experimental animal, which is used for determining the concentration of the therapeutic antibody in said tissue, is reduced by applying an inert reference antibody that does not penetrate into said tissue, whereby the inert reference antibody is administered 2 to 10 minutes prior to obtaining the tissue and blood sample.

Abstract: The invention relates to a phantom for simple calibration and quality assurance in an MR tomograph, having a phantom body (2), measuring aids (10, 11, 12, 13) and an intermediate bottom (14) having an upper and a lower side, wherein the measuring aids (10, 11, 12, 13) and the intermediate bottom (14) are arranged in the phantom body (2) in at least four planes (6, 7, 8, 9) and a first plane (6) comprises as the measuring aid only the measuring fluid (10), a second plane (7) comprises as the measuring aid wedge-shaped elements (11), a third plane (8) comprises as the measuring aid marks (12) of known distance from one another, and a fourth plane (9) comprises as the measuring aid comb-shaped elements (13), wherein the measuring aids (11) of the second plane (7) are arranged on one side of the intermediate bottom (14), the measuring aids (13) of the fourth plane (9) are arranged on the other side of the intermediate bottom (14) and the measuring aids (12) of the third plane (8) are arranged in the intermediate

Abstract: A device and a method for testing the MR-safety of an implant (4). The device includes a phantom (1) that has a test volume filled with a medium (2), wherein the test volume receives the implant (4) to be tested, at least one RF transmitter (3) that emits radio-frequency electromagnetic radiation into the test volume. The device is used for detecting the heating of the implant (4) and/or of the medium (2) surrounding the implant.

Abstract: There is a need for devices and methods which allow for a risk-free and reliable test of the MR-safety of implants outside the human body. For this purpose, the invention proposes a device for testing the MR-safety of an implant (4), comprising a phantom (1) that has a test volume filled with a medium (2), wherein the test volume receives the implant (4) to be tested, at least one RF transmitter (3) that emits radio-frequency electromagnetic radiation into the test volume, and comprising means for detecting the heating of the implant (4) and/or of the medium (2) surrounding said implant. The invention furthermore relates to a method for testing the MR-safety of an implant (4), in which a device of this kind is used.

Abstract: The invention relates to a vessel filter comprising at least one conductor loop (21) which forms the inductance of an electric resonance circuit. According to the invention, the conductor loop (21) forms the vessel filter or parts of a vessel filter. The invention provides a vessel filter which is characterized by good mechanical properties, especially a high degree of flexibility and stability, offering good representability in MR imaging systems.