Patents by Inventor Gregorio Pirozzi

Gregorio Pirozzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification and isolation of novel polypeptides having WW domains and methods of using same
    Patent number: 7279548
    Abstract: Novel polypeptides having WW domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: October 9, 2007
    Assignees: Cytogen Corporation, The University of North Carolina at Chapel Hill
    Inventors: Gregorio Pirozzi, Brian K. Kay, Dana M. Fowlkes
  • Identification and isolation of novel polypeptides having PDZ domains and methods of using same
    Publication number: 20050112552
    Abstract: The invention described herein encompasses the identification and isolation of polypeptides having PDZ domains or functional equivalents thereof. Various methods of use of these polypeptides are described including, but not limited to, targeted drug discovery. The invention also includes nucleotide sequences encoding novel PDZ domains and the proteins encoded thereby. The invention additionally provides for various peptide recognition units that bind to PDZ domains. The present invention also encompasses nucleotide sequences encoding novel WW domains and the polypeptides encoded thereby.
    Type: Application
    Filed: February 23, 2004
    Publication date: May 26, 2005
    Inventors: Juan Herrero, Gregorio Pirozzi, Albert Uveges
  • Novel genes associated with allergic hypersensitivity and mast cell activation
    Publication number: 20030166881
    Abstract: The invention relates generally to the changes in gene expression in mast cells during maturation and in tissues removed from patients with urticaria or allergic hypersensitivity relative to gene expression in mast cells removed from normal subjects. The invention specifically relates to four novel gene families which are differentially expressed in mast cells and allergic hypersensitivity diseases, such as urticaria, compared to normal tissues.
    Type: Application
    Filed: December 7, 2001
    Publication date: September 4, 2003
    Inventors: Karl Nocka, Gregorio Pirozzi, Richard Einstein
  • Identification and isolation of novel polypeptides having WW domains and methods of using same
    Publication number: 20030077577
    Abstract: Novel polypeptides having WW domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Application
    Filed: June 28, 2002
    Publication date: April 24, 2003
    Inventors: Gregorio Pirozzi, Brian K. Kay, Dana M. Fowlkes
  • Identification and isolation of novel polypeptides having WW domains and methods of using same
    Patent number: 6011137
    Abstract: Novel polypeptides having WW domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
    Type: Grant
    Filed: April 3, 1996
    Date of Patent: January 4, 2000
    Assignees: University of North Carolina at Chapel Hill, Cytogen Corp.
    Inventors: Gregorio Pirozzi, Brian K. Kay, Dana M. Fowlkes