Patents by Inventor Gregory A. Howell

Gregory A. Howell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETICALLY MODIFIED MOUSE EXPRESSING HUMAN APOE4 AND MOUSE TREM2 P.R47H AND METHODS OF USE THEREOF
    Publication number: 20240315220
    Abstract: Genetically modified mice characterized by one or more symptoms or signs associated with expression of human APOE4p and mouse Trem2p and relevant to non-familial late-onset Alzheimer's disease are provided wherein the genome of the mouse includes: 1) a DNA sequence encoding a human APOE4 protein (APOE4p) operably linked to a promoter; and 2) a DNA sequence encoding a mouse Trem2 protein having a mutation p.R47H (Trem2p) operably linked to a promoter, such that the mouse expresses human APOE4p and mouse Trem2p. Methods are provided for screening for a compound for use in the treatment of Alzheimer's disease using such genetically modified mice.
    Type: Application
    Filed: March 14, 2024
    Publication date: September 26, 2024
    Applicants: The Jackson Laboratory, Indiana University Research and Technology Corporation
    Inventors: Gareth Howell, Michael Sasner, Gregory Carter, Bruce Lamb
  • Wheel
    Patent number: D889359
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: July 7, 2020
    Assignee: FCA US LLC
    Inventors: Michael C. Gillam, Gregory A. Howell
  • Wheel
    Patent number: D889360
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: July 7, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Gregory A. Howell
  • Lower air dam
    Patent number: D890656
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: July 21, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Everard J Scott, Michael Gillam, Gregory A. Howell
  • Front fender
    Patent number: D890658
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: July 21, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Everard J Scott, Michael Gillam, Gregory A. Howell
  • Vehicle upper grille
    Patent number: D891313
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: July 28, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Everard J Scott, Michael Gillam, Gregory A. Howell
  • Step pad with hitch hole
    Patent number: D891319
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: July 28, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Everard J Scott, Michael Gillam, Gregory A. Howell
  • Side mirror
    Patent number: D891338
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: July 28, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Everard J Scott, Michael Gillam, Gregory A. Howell
  • Wheel
    Patent number: D891345
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: July 28, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Gregory A. Howell
  • Wheel
    Patent number: D891346
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: July 28, 2020
    Assignee: FCA US LLC
    Inventors: Jeremy Glover, Gregory A. Howell
  • Wheel
    Patent number: D895510
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: September 8, 2020
    Assignee: FCA US LLC
    Inventors: Everard J. Scott, Gregory A. Howell
  • Wheel
    Patent number: D895511
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: September 8, 2020
    Assignee: FCA US LLC
    Inventor: Gregory A. Howell
  • Wheel
    Patent number: D896148
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: September 15, 2020
    Assignee: FCA US LLC
    Inventors: Jeremy Glover, Gregory A. Howell
  • Wheel
    Patent number: D896149
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: September 15, 2020
    Assignee: FCA US LLC
    Inventors: Everard J. Scott, Gregory A. Howell
  • Box side panel assembly
    Patent number: D901349
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: November 10, 2020
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Everard J Scott, Michael Gillam, Gregory A. Howell
  • Wheel
    Patent number: D901354
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: November 10, 2020
    Assignee: FCA US LLC
    Inventors: Jeffrey R. Aneiros, Gregory A. Howell
  • Air inlet bezel
    Patent number: D909938
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: February 9, 2021
    Assignee: FCA US LLC
    Inventors: Deyan Ninov, Michael Gillam, Gregory A Howell
  • Front end
    Patent number: D910504
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: February 16, 2021
    Assignee: FCA US LLC
    Inventors: Everard J Scott, Michael Gillam, Gregory A. Howell
  • Automobile body
    Patent number: D1046687
    Type: Grant
    Filed: September 1, 2022
    Date of Patent: October 15, 2024
    Assignee: FCA US LLC
    Inventors: Mark T Allen, Timothy A Doyle, Tome Jovanoski, Chenming Zhang, Gregory A Howell, Joshua T Holly, Nicolas Ren Stone
  • Automobile body
    Patent number: D1048938
    Type: Grant
    Filed: September 1, 2022
    Date of Patent: October 29, 2024
    Assignee: FCA US LLC
    Inventors: Mark T Allen, Gregory A Howell, Irina Zavatski, Kohl J Kohrman, Joshua T Holly, Matthew Dunford, Eugenio Sellaro-Neto