Patents by Inventor Gregory Alan Stephenson

Gregory Alan Stephenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-aminobenzonitrile selective androgen receptor modulators
    Patent number: 8658693
    Abstract: The present invention provides novel selective androgen receptor modulators and their salts and pharmaceutical compositions thereof.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: February 25, 2014
    Assignee: Eli Lilly and Company
    Inventors: Jonathan Edward Green, Prabhakar Kondaji Jadhav, Venkatesh Krishnan, Donald Paul Matthews, Ashraf Saeed, Gregory Alan Stephenson
  • Notch pathway signaling inhibitor compound
    Patent number: 8569286
    Abstract: The present invention provides a compound, or a pharmaceutically acceptable salt or hydrate, and a pharmaceutical composition containing said compound, or a pharmaceutically acceptable salt or hydrate, useful as a Notch pathway signaling inhibitor for the treatment of cancer.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: October 29, 2013
    Assignee: Eli Lilly and Company
    Inventors: Philip Arthur Hipskind, Gregory Alan Stephenson
  • NOTCH PATHWAY SIGNALING INHIBITOR COMPOUND
    Publication number: 20130029972
    Abstract: The present invention provides a compound, or a pharmaceutically acceptable salt or hydrate, and a pharmaceutical composition containing said compound, or a pharmaceutically acceptable salt or hydrate, useful as a Notch pathway signaling inhibitor for the treatment of cancer.
    Type: Application
    Filed: July 18, 2012
    Publication date: January 31, 2013
    Applicant: ELI LILLY AND COMPANY
    Inventors: Philip Arthur HIPSKIND, Gregory Alan STEPHENSON
  • Crystalline (3-cyano-1H-indol-7-yl)-[4-(4-fluorophenethyl) piperazin-1-yl]methanone phosphate
    Patent number: 8188087
    Abstract: The present invention relates to novel crystalline forms of (3-cyano-1H-indol-7-yl)-[4-(4-fluorophenethyl)piperazin-1-yl]methanone phosphate and to pharmaceutical compositions containing said forms.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: May 29, 2012
    Assignee: Merck Patent GmbH
    Inventors: Susan Marie Reutzel-Eden, Gregory Alan Stephenson
  • CRYSTALLINE (3-CYANO-1H-INDOL-7-YL)-[4-(4-FLUOROPHENETHYL) PIPERAZIN-1-YLIMETHANONE PHOSPHATE
    Publication number: 20090221606
    Abstract: The present invention relates to novel crystalline forms of (3-cyano-1H-indol-7-yl)-[4-(4-fluorophenethyl)piperazin-1-yl]methanone phosphate and to pharmaceutical compositions containing said forms.
    Type: Application
    Filed: April 24, 2007
    Publication date: September 3, 2009
    Inventors: Susan Marie Reutzel-Eden, Gregory Alan Stephenson
  • CRYSTALLINE (R)-2-(4-CYCLOPROPANESULPHONYL-PHENYL)-N-PYRAZIN-2-YL-3-(TETRAHYDROPYRAN-4-YL)-PROPIONAMIDE
    Publication number: 20090181981
    Abstract: Crystalline R-2-(4-cyclopropanesulfonyl-phenyl)-N-pyrazin-2-yl-3-(tetrahydropyran-4-yl)-propionamide and methods of its preparation and use are disclosed.
    Type: Application
    Filed: January 7, 2009
    Publication date: July 16, 2009
    Inventors: Jeanette Tower Dunlap, Gregory Alan Stephenson
  • CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1
    Publication number: 20090111800
    Abstract: The present invention discloses novel compounds of Formula (I): having 11?-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11?-HSD type 1 activity.
    Type: Application
    Filed: April 5, 2007
    Publication date: April 30, 2009
    Inventors: Thomas Daniel Aicher, Peter Biagio Anzeveno, Renhua Li, Alexei Pavlovych Krasutsky, Thomas Edward Mabry, Ashraf Saeed, Nancy June Snyder, Gregory Alan Stephenson, Hongqi Tian, Owen Brendan Wallace, Leonard Larry Winneroski, JR., Yanping Xu
  • Lactam compound
    Patent number: 7468365
    Abstract: The present invention provides crystalline (N)-((S)-2-hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one, a crystalline anydrate and dihydrates thereof, compositions comprising (N)-((S)-2-hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one, its crystalline anhydrate or dihydrate, and methods for using the same.
    Type: Grant
    Filed: January 11, 2006
    Date of Patent: December 23, 2008
    Assignees: Eli Lilly and Company, Elan
    Inventors: James Edmund Audia, Benjamin Alan Diseroad, Varghese John, Lee H. Latimer, Jeffrey Scott Nissen, Gregory Alan Stephenson, Eugene D. Thorsett, Jay S. Tung
  • Process for preparing pharmaceutical bulk material having uniform dissolution
    Patent number: 6596307
    Abstract: The present invention provides a process for producing cefaclor crystalline bulk material having a dissolution rate in a capsule of ≧80% in water in 30 minutes. One process route includes reducing the water content of cefaclor dihydrates or bulk material containing cefaclor dihydrate to produce a cefaclor form having a water content ≦2%. The cefaclor having the lower water content can then be rehydrated to a water content from 3.0 to 6.5% without adversely affecting the dissolution rate. An alternative process includes the addition of at least 0.05% of cefaclor related substances to inhibit conversion of the monohydate to the dihydate form.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: July 22, 2003
    Assignee: Eli Lilly and Company
    Inventors: Frank Brown, Jr., Robert Alan Forbes, Arlette Faye Kreager, Michael Vincent Mullen, Gregory Alan Stephenson
  • Olanzapine dihydrate D
    Patent number: 6251895
    Abstract: The present invention provides the novel Dihydrate D 2-methyl-thieno-benzodiazepine and a formulation therefor.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: June 26, 2001
    Assignee: Eli Lilly and Company
    Inventors: Samuel Dean Larsen, John Richard Nichols, Susan Marie Reutzel, Gregory Alan Stephenson
  • Intermediates and process for preparing olanzapine
    Patent number: 6020487
    Abstract: The present invention provides a process for preparing olanzapine and intermediates therefor.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: February 1, 2000
    Assignee: Eli Lilly and Company
    Inventors: Charles Arthur Bunnell, Samuel Dean Larsen, John Richard Nichols, Susan Marie Reutzel, Gregory Alan Stephenson