Abstract: Genetically engineered hematopoietic cells, which express one or more factors that redirect glucose metabolites, and optionally a chimeric receptor polypeptide (e.g., an antibody-coupled T cell receptor (ACTR) polypeptide, a chimeric antigen receptor (CAR) polypeptide, or a TCR polypeptide) capable of binding to a target antigen of interest. Also disclosed herein are uses of the engineered hematopoietic cells for inhibiting cells expressing a target antigen in a subject in need thereof.

Abstract: Disclosed herein are genetically engineered hematopoietic cells, which express one or more Krebs cycle modulating polypeptides, and optionally a chimeric receptor polypeptide (e.g., an antibody-coupled T cell receptor (ACTR) polypeptide or a chimeric antigen receptor (CAR) polypeptide) capable of binding to a target antigen of interest. Also disclosed herein are uses of the engineered hematopoietic cells for inhibiting cells expressing a target antigen in a subject in need thereof.

Abstract: Disclosed herein are genetically engineered hematopoietic cells, which express one or more Krebs cycle modulating polypeptides, and optionally a chimeric receptor polypeptide (e.g., an antibody-coupled T cell receptor (ACTR) polypeptide or a chimeric antigen receptor (CAR) polypeptide) capable of binding to a target antigen of interest. Also disclosed herein are uses of the engineered hematopoietic cells for inhibiting cells expressing a target antigen in a subject in need thereof.

Abstract: A system for analyzing a packet-based network includes a wireless network analysis processing device that is configured to receive correlated packet records representative of the order in which corresponding packets are transmitted in a wireless network. The correlated packet records include media access control (MAC) layer data and network layer data for each corresponding packet. The MAC layer data and network layer data are processed to generate network topology data representative of the network topology, generate packet flow data representative of the flow of packets between devices at the MAC layer and across the network at the network layer, and measurement data relating to the packet flow data.

Abstract: A system for analyzing a packet-based network includes a correlator processor that is configured to receive packet records corresponding to packets communicated over a network and store the packet records in a data store. The correlator processor is also configured to generate correlated packet records from the packet records stored in the data store, the correlated packet records representative of the order in which the packets were transmitted in the network.