Patents by Inventor Gregory Basarab

Gregory Basarab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial piperdine derivatives
    Patent number: 8399489
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: March 19, 2013
    Assignee: Astrazeneca AB
    Inventors: Gregory Basarab, Brian Dangel, Paul Robert Fleming, Michael Barry Gravestock, Oluyinka Green, Sheila Irene Hauck, Pamela Hill, Kenneth Gregory Hull, George Mullen, Haihong Ni, Brian Sherer, Fei Zhou
  • 2-(PIPERIDIN-1-YL)-4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS
    Publication number: 20120028979
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Application
    Filed: October 6, 2011
    Publication date: February 2, 2012
    Inventors: Gregory BASARAB, Pamela HILL, Brian SHERER, Fei ZHOU
  • Piperidine compounds for use in the treatment of bacterial infections
    Patent number: 8071605
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: December 6, 2011
    Assignee: AstraZeneca AB
    Inventors: Gregory Basarab, Pamela Hill, Brian Sherer, Fei Zhou
  • PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY
    Publication number: 20100286181
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Application
    Filed: August 16, 2007
    Publication date: November 11, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Gregory Basarab, Pamela Hill, Kenneth Gregory Hull
  • ANTIBACTERIAL PIPERDINE DERIVATIVES
    Publication number: 20100179150
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Application
    Filed: February 16, 2006
    Publication date: July 15, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Gregory Basarab, Brian Dangel, Paul Robert Fleming, Michael Barry Gravestock, Oluyinka Green, Sheila Irene Hauck, Pamela Hill, Kenneth Gregory Hull, George Mullen, Brian Sherer, Fei Zhou, Haihong Ni
  • PIPERIDINE COMPOUNDS AND USES THEREOF - 596
    Publication number: 20100173909
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Application
    Filed: December 10, 2009
    Publication date: July 8, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Gregory BASARAB, Pamela HILL, Brian SHERER, Fei ZHOU
  • Antibacterial Pyrrolopyridines, Pyrrolopyrimidines and Pyrroloazepines-154
    Publication number: 20080312211
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described: formula (I). Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Application
    Filed: December 19, 2006
    Publication date: December 18, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Gregory Basarab, Haihong Ni, Brian Sherer, Fei Zhou
  • PIPERDINE COMPOUNDS AND USES THEREOF-911
    Publication number: 20080312255
    Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
    Type: Application
    Filed: June 11, 2008
    Publication date: December 18, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Gregory Basarab, Pamela Hill, Fei Zhou
  • Fused heterocycles as inhibitors of glutamate racemase(MURI)
    Patent number: 7371757
    Abstract: This invention relates to novel compounds having formula: (I) or (II) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of H. pylori infection.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: May 13, 2008
    Assignee: AstraZeneca AB
    Inventors: Marshall Morningstar, Gregory Basarab, Charles Joseph Eyermann, Madhu Gowravaram, Oluyinka Green, Andrew Kiely, Lawrence MacPherson, Nguyen Thanh
  • Novel Fused Heterocycles and Uses Thereof
    Publication number: 20070275954
    Abstract: This invention relates to novel compounds having the Formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of H. pylori infection.
    Type: Application
    Filed: May 19, 2005
    Publication date: November 29, 2007
    Applicant: AstraZeneca AB
    Inventors: Gregory Basarab, Charles Eyermann, Bolin Geng, Madhusudhan Gowravaram, James Loch III, Lawrence MacPherson, Marshall Morningstar, George Mullen, Alex Staz, Andrew Kiely
  • Pyrazolo[3,4-d]pyrimidines inhibiting infections
    Patent number: 7285558
    Abstract: Compounds having the general formula and pharmaceutical compositions containing them, and their use in the treatment or prophylaxis of H. pylori infection.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: October 23, 2007
    Assignee: AstraZeneca AB
    Inventors: Gregory Basarab, Joseph Eyermann, Madhusudhan Gowravaram, Oluyinka Green, Lawrence MacPherson, Marshall Morningstar, Thanh Nguyen
  • Pyrazolo [3,4-d] pyrimidine derivatives and their use in the treatment of h.pylori infection
    Publication number: 20070004761
    Abstract: This invention relates to novel compounds having the structural diagram (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of H. pylori infection.
    Type: Application
    Filed: December 19, 2003
    Publication date: January 4, 2007
    Inventors: Gregory Basarab, Joseph Eyermann, Madhusudhan Gowravaram, Ohryinka Green, Lawrence MacPherson, Marshall Morningstar, Thanh Nguyen
  • Fused heterocycles as inhibitors of glutamate racemase(muri)
    Publication number: 20060252781
    Abstract: This invention relates to novel compounds having formula: (I) or (II) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of H. pylori infection.
    Type: Application
    Filed: August 12, 2004
    Publication date: November 9, 2006
    Inventors: Gregory Basarab, Charles Eyermann, Madhusudhhan Gowravaram, Oluyinka Green, Andrew Kiely, Lawrence Macpherson, Marshall Morningstar, Nguyen Thanh
  • FUNGICIDAL CARBOXAMIDES
    Publication number: 20060178425
    Abstract: Compounds of Formula I are disclosed which are useful as fungicides wherein X is —O—, —CH(R11)— or ?C(R11)—; R1 is H or C1-C2 alkyl; R2 is H; C1-C6 alkyl; C3-C6 cycloalkyl; or phenyl optionally substituted with halogen, cyano, C1-C2 alkyl or C1-C2 alkoxy; and R3—R11 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound of Formula I.
    Type: Application
    Filed: March 2, 2001
    Publication date: August 10, 2006
    Inventors: Gregory Basarab, Douglas Jordan, Thomas Lessen, Stephen Hansen
  • FUNGICIDAL CARBOXAMIDES
    Publication number: 20060025472
    Abstract: Compounds of Formula I are disclosed which are useful as fungicides wherein Q is X is —O—, —CH(R11)— or ?C(R11)—; R1 is H or C1-C2 alkyl; R2 is H; C1-C6 alkyl; C3-C6 cycloalkyl; or phenyl optionally substituted with halogen, cyano, C1-C2 alkyl or C1-C2 alkoxy; and R3-R11 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound of Formula I.
    Type: Application
    Filed: March 2, 2001
    Publication date: February 2, 2006
    Inventors: Gregory Basarab, Douglas Jordan, Thomas Lessen, Stephen Hansen
  • Pyrazolo[3,4-d]pyrimidines inhibiting h. pylori infections
    Publication number: 20040254183
    Abstract: Compounds having the general formula 1
    Type: Application
    Filed: June 14, 2004
    Publication date: December 16, 2004
    Inventors: Gregory Basarab, Joseph Eyermann, Madhusudhan Gowravaram, Oluyinka Green, Lawrence MacPherson, Marshall Morningstar, Thanh Nguyen