Abstract: A spring post fastening system includes a reception member including a bottom interference member and a center protrusion extending from the bottom interference member, the center protrusion defining a center reception orifice and a retention notch, and an engagement member~including a top interference member and an engagement protrusion coupled to the top interference member. The engagement protrusion includes at least one notch engagement protrusion. Further, the engagement protrusion is configured to slideably engage the reception orifice.

Abstract: Method for alleviating testicular pain in a patient in need thereof. The method can comprise the step of locally administering a neurotoxin (e.g., a botulinum toxin) to at least one anatomical site selected from the group consisting of a testicle and a tissue associated with the testicle of the patient.

Abstract: Skin topographical methods for quantifying pharmacodynamic parameters of a paralytic effect of a Clostridial toxin, such as a botulinum toxin upon a muscle, such as a frontalis muscle. The methods are effective in determining the potency of a Clostridial toxin, and in comparing toxins. For example, wrinkle reduction effects caused by one or more neurotoxins may be monitored, and differences in effects correspond to differences of neurotoxins.

Abstract: Skin topographical methods for quantifying pharmacodynamic parameters of a paralytic effect of a Clostridial toxin, such as a botulinum toxin upon a muscle, such as a frontalis muscle. The methods are effective in determining the potency of a Clostridial toxin, and in comparing toxins. For example, wrinkle reduction effects caused by one or more neurotoxins may be monitored, and differences in effects correspond to differences of neurotoxins.

Abstract: Skin topographical methods for quantifying pharmacodynamic parameters of a paralytic effect of a Clostridial toxin, such as a botulinum toxin upon a muscle, such as a frontalis muscle. The methods are effective in determining the potency of a Clostridial toxin, and in comparing toxins. For example, wrinkle reduction effects caused by one or more neurotoxins may be monitored, and differences in effects correspond to differences of neurotoxins.

Abstract: Methods for treating an injured muscle by local administration of a neurotoxin, such as a botulinum toxin, to promote healing and/or to reduce the pain associated with an injured muscle.

Abstract: Methods of treating a urethral stricture in a patient. The methods can include the step of administering an therapeutically effective amount of a botulinum toxin directly to a urethra of the patient, for example by use of a stent from which the botulinum toxin can elute or diffuse, thereby treating the urethra stricture.

Abstract: The present invention provides for methods of treating cardiovascular diseases in a mammal. The methods include a step of administering an effective amount of a botulinum toxin directly to a blood vessel of a mammal thereby treating a cardiovascular disease.

Abstract: Methods for treating an injured muscle by local administration of a neurotoxin, such as a botulinum toxin, to promote healing and/or to reduce the pain associated with an injured muscle.

Abstract: Skin topographical methods for quantifying pharmacodynamic parameters of a paralytic effect of a Clostridial toxin, such as a botulinum toxin upon a muscle, such as a frontalis muscle. The methods are effective in determining the potency of a Clostridial toxin, and in comparing toxins. For example, wrinkle reduction effects caused by one or more neurotoxins may be monitored, and differences in effects correspond to differences of neurotoxins.

Abstract: A botulinum toxin system for in vivo release of therapeutic amounts of botulinum toxin in a human patient over a prolonged period of time. The system may be a suppository effective in treating one or more anorectal disorders or conditions, such as anal fissures, hemorrhoids, anismus, and the like.