Patents by Inventor Gregory Butchko

Gregory Butchko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and apparatus for removal of DNA, viruses and endotoxins
    Patent number: 5221483
    Abstract: A single filtration device containing coated filter membranes and absolute pore filters is provided in which the membranes and absolute pore filters are present in two sections of the filter device. The filter device will remove up to about 98% of the endotoxins in addition to removing viruses with an efficiency of at least 4.6.times.10.sup.5 and DNA to less than 10 picograms per 500 mg sample.
    Type: Grant
    Filed: November 4, 1991
    Date of Patent: June 22, 1993
    Assignee: Coulter Corporation
    Inventors: Stephan D. Glenn, Gregory Butchko, Edward O'Connell, Paulette Smariga
  • Process and apparatus for removal of DNA and viruses
    Patent number: 5076933
    Abstract: A single filtration device containing coated filter membranes and absolute pore filters is provided in which the membranes and absolute pore filters are present in two sections of the filter device. The filter device will remove viruses, as modeled by type-C Xenotropic retrovirus, with an efficiency of at least 4.6.times.10.sup.5 ; remove DNA from levels of 10 .mu.g/sample to levels below 10 picograms per 500 mg sample of monoclonal antibody; and will remove at least 97% of some bacterial endotoxins.
    Type: Grant
    Filed: June 29, 1990
    Date of Patent: December 31, 1991
    Assignee: Coulter Corporation
    Inventors: Stephan D. Glenn, Edward O'Connell, Paulette Smariga, Gregory Butchko