Abstract: Systems and methods for performing apheresis procedures, including photopheresis. The systems and methods utilize a disposable fluid circuit that can be converted from a double needle configuration to a single needle configuration and from a single needle configuration to a double needle configuration. A controller directs the action of system pumps to clear potentially stagnant blood residing in the fluid circuit, tracks system parameters and status before and after conversion, and verifies that the procedure may proceed in its new configuration.

Abstract: A flow circuit for a blood treatment system includes flow cassettes, a separation chamber fluidically connected to the cassettes, tubings fluidically connecting the cassettes and the separation chamber, the tubings including a plasma tubing including a first column connector, a Luer activated port, and a check valve. The flow circuit has a first configuration for a replacement fluid therapeutic plasma exchange procedure in which the first column connector has first and second mating parts connected to one another, and a second configuration for an adsorption therapeutic plasma exchange procedure in which the flow circuit further comprises an adsorption device having a second column connector and the adsorption device is connected in line with plasma tubing and the first and second mating parts of the first column connector are connected to corresponding first and second parts of the second column connector.

Abstract: Systems and methods for the optimization of blood collection and therapies using an automated blood cell separator are disclosed. The systems and methods calculate or determine recommended settings based on, among other things, one or more of historical collection data, set defaults, contamination limits, blood, and blood component characteristics.

Abstract: Systems and methods for performing apheresis procedures, including photopheresis, are disclosed. The systems and methods utilize a disposable fluid circuit that can be converted from a double needle configuration to a single needle configuration and from a single needle configuration to a double needle configuration. A controller directs the action of system pumps to clear potentially stagnant blood residing in the fluid circuit, tracks system parameters and status before and after conversion, and verifies that the procedure may proceed in its new configuration.