Abstract: The present invention is for an autonomous aerial vehicle that enables near real-time and offline data processing among heterogenous devices that are in unreliable or unconnected network service areas, wherein the heterogenous devices are associated with heavy industrial systems. The autonomous aerial vehicle may obtain data from a first physical asset, and segment the obtained data as suitable for a local area compute node and/or a cloud compute node. The autonomous aerial vehicle may identify a location associated with the one or more destination devices and may compute a flight path to the destination location. The aerial device may hereafter travel to the destination location and upload relevant data to the at least one destination upon arrival.

Abstract: The present invention is for an autonomous aerial vehicle that enables near real-time and offline data processing among heterogenous devices that are in unreliable or unconnected network service areas, wherein the heterogenous devices are associated with heavy industrial systems. The autonomous aerial vehicle may obtain data from a first physical asset, and segment the obtained data as suitable for a local area compute node and/or a cloud compute node. The autonomous aerial vehicle may identify a location associated with the one or more destination devices and may compute a flight path to the destination location. The aerial device may thereafter travel to the destination location and upload relevant data to the at least one destination upon arrival.

Abstract: Obtaining location data in a novel way is considered to be a part of this invention. An exemplary method for doing so includes identifying first positioning information for a data delivery vehicle based at least in part on a plurality of positioning signals received at the data delivery vehicle from a set of satellites of a global navigation satellite system (GNSS). The example method comprises obtaining relative position information associated with a position vector from the data delivery vehicle to a remote vehicle, the remote vehicle being unable to receive the plurality of positioning signals from the set of satellites. The example method comprises determining second positioning information for the remote vehicle based at least in part on the first positioning information and the relative position information. The example method comprises transmitting the second positioning information to the remote vehicle.

Abstract: A shaft coupler having first and second spindles adapted to be secured to a first and second output shafts of first and second motors, respectively. A locker ring is assembled to the first spindle, and a locker carrier is assembled to the second spindle. A coil is carried by the locker carrier and switches between an energized state wherein the coil shifts the locker ring to slide into engagement with the second spindle to lock the first and second output shafts together, and a deenergized state wherein a spring biases the locker ring out of engagement with the second spindle to unlock the first and second output shafts from each other. A first set of locking teeth are disengaged from a second set of locking teeth when the coil is deenergized, and are engaged when the coil is energized.

Abstract: A differential includes a disconnect feature. When in a disengaged state, the drive gear is decoupled from the differential carrier. As a result, the portions of the powertrain that would provide propulsion through the differential may be stationary and parasitic drag is decreased. The differential is transitioned into an engaged state by providing electrical current in a solenoid coil fixed to the housing. A solenoid piston acts through a thrust bearing to slide a sleeve, thereby coupling the carrier to the drive gear.

Abstract: Described herein are alterable optical structures. Also described herein are methods of altering same.

Abstract: Obtaining location data in a novel way is considered to be a part of this invention. An exemplary method for doing so includes identifying first positioning information for a data delivery vehicle based at least in part on a plurality of positioning signals received at the data delivery vehicle from a set of satellites of a global navigation satellite system (GNSS). The example method comprises obtaining relative position information associated with a position vector from the data delivery vehicle to a remote vehicle, the remote vehicle being unable to receive the plurality of positioning signals from the set of satellites. The example method comprises determining second positioning information for the remote vehicle based at least in part on the first positioning information and the relative position information. The example method comprises transmitting the second positioning information to the remote vehicle.

Abstract: A shaft coupler having first and second spindles adapted to be secured to a first and second output shafts of first and second motors, respectively. A locker ring is assembled to the first spindle, and a locker carrier is assembled to the second spindle. A coil is carried by the locker carrier and switches between an energized state wherein the coil shifts the locker ring to slide into engagement with the second spindle to lock the first and second output shafts together, and a deenergized state wherein a spring biases the locker ring out of engagement with the second spindle to unlock the first and second output shafts from each other. A first set of locking teeth are disengaged from a second set of locking teeth when the coil is deenergized, and are engaged when the coil is energized.

Abstract: The present invention is for an autonomous aerial vehicle that enables near real-time and offline data processing among heterogenous devices that are in unreliable or unconnected network service areas, wherein the heterogenous devices are associated with heavy industrial systems. The autonomous aerial vehicle may obtain data from a first physical asset, and segment the obtained data as suitable for a local area compute node and/or a cloud compute node. The autonomous aerial vehicle may identify a location associated with the one or more destination devices and may compute a flight path to the destination location. The aerial device may thereafter travel to the destination location and upload relevant data to the at least one destination upon arrival.

Abstract: A system is provided comprising a robotic instrument for use with a tool. In some versions, the robotic instrument comprises a hand-held portion to be held by a user and a tool support movably coupled to the hand-held portion to support the tool. The robotic instrument further includes an actuator assembly operatively attached to the tool support and the hand-held portion and configured to move the tool support relative to the hand-held portion in a plurality of degrees of freedom. The robotic instrument may includes a handle alignment member extending from the hand-held portion. At least a portion of the handle alignment member and a tool plane defined by the tool are aligned when the tool support has an optimal range of motion relative to the hand-held portion.

Abstract: This application is directed to a surveillance camera system including a magnet mount for physically receiving a camera module. The camera module includes a housing having an exterior surface of a first shape. A surface of the magnet mount has a second shape that is substantially concave and complementary to the first shape, and is configured to engage the exterior surface of the housing of the camera module. A magnetic material is disposed inside the magnet mount and configured to magnetically couple to a magnetic material of the camera module. A friction pad is embedded on the surface of the magnet mount, has a substantially concave shape and protrudes beyond the second surface. The friction pad is configured to come into contact with the exterior surface of the housing of the camera module at least via a peripheral edge of the substantially concave friction pad.

Abstract: The invention provides compositions and methods comprising biomarker genes for identifying subjects that will respond to human MAP kinase kinase (MEK) inhibitor therapies, compositions and methods comprising biomarker genes for identifying subjects that will respond to MEK inhibitor/target of rapamycin complex (TORC) inhibitor combination therapies, and compositions and methods comprising biomarker genes for identifying subjects that will respond to MEK inhibitor/chemotherapy combination therapies.

Abstract: The present disclosure provides a method for determining a genotype of one or more biomarker genes in a tumor sample of a subject afflicted with cancer, the method comprising determining a genotype of one or more biomarker genes in the tumor sample and classifying a subject as sensitive or resistant to a therapy comprising a SHP2 inhibitor based on the genotype the one or more biomarker genes in the tumor sample.

Abstract: The present invention is for an autonomous aerial vehicle that enables near real-time and offline data processing among heterogenous devices that are in unreliable or unconnected network service areas, wherein the heterogenous devices are associated with heavy industrial systems. The autonomous aerial vehicle may obtain data from a first physical asset, and segment the obtained data as suitable for a local area compute node and/or a cloud compute node. The autonomous aerial vehicle may identify a location associated with the one or more destination devices and may compute a flight path to the destination location. The aerial device may thereafter travel to the destination location and upload relevant data to the at least one destination upon arrival.

Abstract: A vehicle includes an engine, an electric machine, a torque converter, a weldment, an engine disconnect clutch, and a torque converter lockup clutch. The engine has a crankshaft. The electric machine has a rotor. The torque converter has an impeller and a turbine. The weldment is configured to rotate about an axis and to transfer power from the crankshaft and the rotor to the impeller. The weldment has a first hub, a second hub, a torque converter cover, an impeller housing, and a third hub. The engine disconnect clutch is configured to rotatably connect and disconnect the crankshaft to and from the weldment. The torque converter lockup clutch is configured to rotatably connect and disconnect the turbine to and from the weldment.

Abstract: An apparatus for preparing food is provided, and includes a food chamber sized to receive at least one food item, a cutting structure configured to cut the at least one food item when pressed into contact therewith, an impeller for impelling the at least one food item into contact with the cutting structure, a liquid chamber for storing a liquid, a heating system for heating the liquid, and a liquid introduction system in communication with the liquid chamber, the liquid introduction system being operable to introduce at least one of a liquid mist and a liquid spray in the food chamber.

Abstract: Obtaining location data in a novel way is considered to be a part of this invention. An exemplary method for doing so includes identifying first positioning information for a data delivery vehicle based at least in part on a plurality of positioning signals received at the data delivery vehicle from a set of satellites of a global navigation satellite system (GNSS). The example method comprises obtaining relative position information associated with a position vector from the data delivery vehicle to a remote vehicle, the remote vehicle being unable to receive the plurality of positioning signals from the set of satellites. The example method comprises determining second positioning information for the remote vehicle based at least in part on the first positioning information and the relative position information. The example method comprises transmitting the second positioning information to the remote vehicle.

Abstract: Disclosed herein are systems and methods for enabling at least one autonomous device to traverse a three-dimensional space. An example system may comprise a first autonomous vehicle comprising a first sensor suite. The first autonomous vehicle may traverse the three-dimensional space in accordance with a path planned vector. The path planned vector may be dynamically updated based on a first vector associated with a first object identified based on data received from the first sensor suite. The example system may comprise a first aerial vehicle comprising a second sensor suite. The first aerial vehicle may traverse the three-dimensional space based on at least one of data provided by the second sensor suite, the first sensor suite, and other aerial vehicles. The path planned vector may be dynamically updated based on data received from at least one of the first sensor suite, the second sensor suite, and cloud interface data.

Abstract: Method(s) include projecting a support toolpath into a current layer of a model, removing any pieces within an expanded version of a current boundary of the model, generating a support toolpath for the current layer, adding a height increase to portion(s) of model toolpath(s) for the higher layer of the model that overlie the support toolpath generated for the current layer, connecting the support toolpath and the projected support toolpath to form a connected support toolpath, overlaying the connected support toolpath with a next boundary of the model in a lower layer of the model, adding a height increase to portion(s) of the connected support toolpath that fall within the next boundary of the model in the lower layer of the model, and repeating the process through layers of the model to form support toolpaths for support walls for the object to be manufactured by the extrusion printer.

Abstract: The present disclosure is directed to compounds of Formula (I), or pharmaceutically acceptable salts thereof and compounds of Formula (II), or pharmaceutically acceptable salts thereof, that modulate stimulator of interferon genes (STING), compositions comprising such compounds, and methods of using same for the treatment of disorders such as cancer and autoimmune disease.