Patents by Inventor Gregory Delgado

Gregory Delgado has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CD28 COMPOSITIONS
    Publication number: 20250043001
    Abstract: Provided herein are novel anti-CD28 x anti-STEAP1 and anti-CD28 x anti-CEACAM5 antibodies and methods of using such antibodies for the treatment of related cancers.
    Type: Application
    Filed: March 14, 2024
    Publication date: February 6, 2025
    Inventors: Gregory Moore, Viralkumar Rameshkumar Davra, Dong Hyun Nam, Veronica Gusti Zeng, Michael Hedvat, Jing Qi, Rumana Rashid, Patrick Arpp, Ernesto Delgado, ChaoFang Tan, Heather Preciado Jimenez, Charles G. Bakhit, Juan Diaz
  • Method of modulating tetrotodoxin-resistant sodium channel
    Patent number: 7122325
    Abstract: The present invention relates to a voltage-gated sodium channel present in peripheral nerve tissue that is tetrodotoxin-resistant. One aspect of the present invention is purified and isolated DNA encoding this sodium channel. Another aspect of the present invention is the recombinant protein expressed by this DNA, expression vectors comprising the DNA sequence, and host cells transformed with these expression vectors. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-resistant sodium channel as a therapeutic target for compounds to treat disorders of the peripheral nervous system.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: October 17, 2006
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Ronald Herman, Stephen Gregory Delgado, Linda Marie Fish, Lakshmi Sangameswaran, Douglas Kenneth Rabert
  • Cloned peripheral nerve, tetrodotoxin-resistant sodium channel alpha-subunit
    Publication number: 20030096360
    Abstract: The present invention relates to a voltage-gated sodium channel present in peripheral nerve tissue that is tetrodotoxin-resistant. One aspect of the present invention is purified and isolated DNA encoding this sodium channel. Another aspect of the present invention is the recombinant protein expressed by this DNA, expression vectors comprising the DNA sequence, and host cells transformed with these expression vectors. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-resistant sodium channel as a therapeutic target for compounds to treat disorders of the peripheral nervous system.
    Type: Application
    Filed: August 1, 2002
    Publication date: May 22, 2003
    Inventors: Ronald Herman, Stephen Gregory Delgado, Linda Marie Fish, Lakshmi Sangameswaran, Douglas Kenneth Rabert
  • Human peripheral nerve, tetrodotoxin-resistant sodium channel &agr;-subunit polypeptide
    Patent number: 6479259
    Abstract: The present invention relates to a voltage-gated sodium channel present in peripheral nerve tissue that is tetrodotoxin-resistant. One aspect of the present invention is purified and isolated DNA encoding this sodium channel. Another aspect of the present invention is the recombinant protein expressed by this DNA, expression vectors comprising the DNA sequence, and host cells transformed with these expression vectors. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-resistant sodium channel as a therapeutic target for compounds to treat disorders of the peripheral nervous system.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: November 12, 2002
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Ronald Herman, Stephen Gregory Delgado, Linda Marie Fish, Lakshmi Sangameswaran, Douglas Kenneth Rabert
  • Cloned tetrodotoxin-sensitive sodium channel &agr;-subunit and a splice variant thereof
    Patent number: 6335172
    Abstract: DNA encoding for a voltage-gated, TTX-sensitive sodium channel is isolated. Also disclosed are polypeptide products of recombinant expression of these DNA sequences, expression vectors comprising the DNA sequences, and host cells transformed with these expression vectors. Other aspects of this invention are peptides whose sequences are based on the amino acid sequences deduced from these DNA sequences, antibodies specific for such proteins and peptides, procedures for detection and quantitation of such proteins, and nucleic acids related thereto. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-sensitive sodium channel as a therapeutic target for compounds.
    Type: Grant
    Filed: October 21, 1999
    Date of Patent: January 1, 2002
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Stephen Gregory Delgado, Paul Shartzer Dietrich, Linda Marie Fish, Ronald Charles Herman, Lakshmi Sangameswaran
  • Cloned peripheral nerve, tetrodotoxin-resistant sodium channel &agr;-subunit
    Patent number: 6184349
    Abstract: The present invention relates to a voltage-gated sodium channel present in peripheral nerve tissue that is tetrodotoxin-resistant. One aspect of the present invention is purified and isolated DNA encoding this sodium channel. Another aspect of the present invention is the recombinant protein expressed by this DNA, expression vectors comprising the DNA sequence, and host cells transformed with these expression vectors. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-resistant sodium channel as a therapeutic target for compounds to treat disorders of the peripheral nervous system.
    Type: Grant
    Filed: April 15, 1997
    Date of Patent: February 6, 2001
    Assignee: Syntex (USA) Inc.
    Inventors: Ronald Herman, Stephen Gregory Delgado, Linda Marie Fish, Lakshmi Sangameswaran, Douglas Kenneth Rabert
  • Cloned tetrodotoxin-sensitive sodium channel .alpha.-subunit and a splice variant thereof
    Patent number: 6030810
    Abstract: DNA encoding for a voltage-gated, TTX-sensitive sodium channel is isolated. Also disclosed are polypeptide products of recombinant expression of these DNA sequences, expression vectors comprising the DNA sequences, and host cells transformed with these expression vectors. Other aspects of this invention are peptides whose sequences are based on the amino acid sequences deduced from these DNA sequences, antibodies specific for such proteins and peptides, procedures for detection and quantitation of such proteins, and nucleic acids related thereto. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-sensitive sodium channel as a therapeutic target for compounds.
    Type: Grant
    Filed: February 16, 1998
    Date of Patent: February 29, 2000
    Inventors: Stephen Gregory Delgado, Paul Shartzer Dietrich, Linda Marie Fish, Ronald Charles Herman, Lakshmi Sangameswaran
  • Fractionating starch hydrolysates
    Patent number: 5194094
    Abstract: A low DE starch hydrolysate is fractionated using a strong base ion exchange resin in hydrophobic anion form. Fractionated acyclic limit dextrins from a cyclodextrin glycosyl transferase digest are found to have extremely long term clarity.
    Type: Grant
    Filed: June 12, 1991
    Date of Patent: March 16, 1993
    Assignee: American Maize-Products Company
    Inventors: Robert Ammeraal, Gregory Delgado
  • Method for making a reduced fat foodstuff
    Patent number: 4981709
    Abstract: The method for making a reduced fat foodstuff entails replacing at least a portion of the fat and/or oil in the foodstuff with an aqueous dispersion of a hydroxypropylated starch having a degree of substitution of above 0.04 and an apparent amylose content of about 40%. A high amylose corn starch is the preferred starch base. a paste made from the dispersion is translucent and tends not to retrograde.
    Type: Grant
    Filed: July 19, 1989
    Date of Patent: January 1, 1991
    Assignee: American Maize-Products Company
    Inventors: Susan L. Furcsik, David J. Mauro, Edward DeBoer, Kenneth Yahl, Gregory Delgado