Patents by Inventor Gregory Dietsch

Gregory Dietsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TYK2 inhibitors and uses thereof
    Patent number: 12600721
    Abstract: Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: April 14, 2026
    Assignee: SUDO BIOSCIENCES LIMITED
    Inventors: Anjali Pandey, Gregory Dietsch, Bhaskar Chaudhuri, Seetharaman Manojveer, Mahesh Thakkar, Athisayamani Jeyaraj Duraiswamy, Sukesh Kalva
  • SUBSTITUTED PYRIDINES, PYRIDAZINES, PYRIMIDINES, AND 1,2,4-TRIAZINES AS TYK2 INHIBITORS
    Publication number: 20250011335
    Abstract: Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: September 12, 2024
    Publication date: January 9, 2025
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • SUBSTITUTED PYRIDINES AND PYRIDAZINES AS TYK2 INHIBITORS
    Publication number: 20240391934
    Abstract: Described herein are compounds of Formula (XIV) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: August 1, 2024
    Publication date: November 28, 2024
    Inventors: Anjali PANDEY, Gregory DIETSCH, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • SUBSTITUTED PYRIDINES, PYRIDAZINES, AND PYRIMIDINES AS TYK2 INHIBITORS
    Publication number: 20240383916
    Abstract: Described herein are compounds of Formula (XIII) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 21, 2024
    Inventors: Anjali PANDEY, Gregory DIETSCH, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • Substituted pyridines, pyridazines, pyrimidines, and 1,2,4-triazines as TYK2 inhibitors
    Patent number: 12122785
    Abstract: Described herein are compounds of Formula (I) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Grant
    Filed: January 27, 2023
    Date of Patent: October 22, 2024
    Assignee: SUDO BIOSCIENCES LIMITED
    Inventors: Anjali Pandey, Gregory Dietsch, Bhaskar Chaudhuri, Seetharaman Manojveer, Mahesh Thakkar, Athisayamani Jeyaraj Duraiswamy, Sukesh Kalva
  • Substituted pyridines and pyridazines as TYK2 inhibitors
    Patent number: 12103937
    Abstract: Described herein are compounds of Formula (XIV) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Grant
    Filed: February 3, 2023
    Date of Patent: October 1, 2024
    Assignee: SUDO BIOSCIENCES LIMITED
    Inventors: Anjali Pandey, Gregory Dietsch, Seetharaman Manojveer, Mahesh Thakkar, Athisayamani Jeyaraj Duraiswamy, Sukesh Kalva
  • Substituted pyridines, pyridazines, and pyrimidines as TYK2 inhibitors
    Patent number: 12084458
    Abstract: Described herein are compounds of Formula (XIII) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Grant
    Filed: February 3, 2023
    Date of Patent: September 10, 2024
    Assignee: SUDO BIOSCIENCES LIMITED
    Inventors: Anjali Pandey, Gregory Dietsch, Seetharaman Manojveer, Mahesh Thakkar, Athisayamani Jeyaraj Duraiswamy, Sukesh Kalva
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20240199610
    Abstract: Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: February 16, 2022
    Publication date: June 20, 2024
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20240189309
    Abstract: Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: February 16, 2022
    Publication date: June 13, 2024
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20240124440
    Abstract: Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: December 16, 2021
    Publication date: April 18, 2024
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Swapan Kumar SAMANTA, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • SUBSTITUTED PYRIDINES, PYRIDAZINES, PYRIMIDINES, AND 1,2,4-TRIAZINES AS TYK2 INHIBITORS
    Publication number: 20230242546
    Abstract: Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: January 27, 2023
    Publication date: August 3, 2023
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20230183264
    Abstract: Described herein are triazole compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: February 3, 2023
    Publication date: June 15, 2023
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20230174553
    Abstract: Described herein are triazole compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: February 3, 2023
    Publication date: June 8, 2023
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • Substituted pyridines, pyridazines, pyrimidines, and 1,2,4-triazines as TYK2 inhibitors
    Patent number: 11613548
    Abstract: Described herein are compounds of Formula (XVII) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of Using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: March 28, 2023
    Assignee: SUDO BIOSCIENCES LIMITED
    Inventors: Anjali Pandey, Gregory Dietsch, Bhaskar Chaudhuri, Seetharaman Manojveer, Mahesh Thakkar, Athisayamani Jeyaraj Duraiswamy, Sukesh Kalva
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20220281885
    Abstract: Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.
    Type: Application
    Filed: May 5, 2022
    Publication date: September 8, 2022
    Inventors: Anjali PANDEY, Gregory DIETSCH, Bhaskar CHAUDHURI, Seetharaman MANOJVEER, Mahesh THAKKAR, Athisayamani Jeyaraj DURAISWAMY, Sukesh KALVA
  • Substituted benzoazepines as toll-like receptor modulators
    Patent number: 9655904
    Abstract: Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-versus-host disease.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: May 23, 2017
    Assignees: VENTIRX PHARMACEUTICALS, INC., ARRAY BIOPHARMA, INC.
    Inventors: James Jeffry Howbert, Gregory Dietsch, Robert Hershberg, Laurence E. Burgess, Joseph P. Lyssikatos, Brad Newhouse, Hong-Woon Yang
  • TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE
    Publication number: 20160331758
    Abstract: The present invention is directed generally to stable formulations of a TLR agonist preferably a TLR7 or a TLR8 agonist, for use in the treatment of cancer, preferably solid tumors and lymphomas. Specifically, the present invention is directed to stable formulations of up to 50 mg/ml of a TLR agonist which comprise a cyclodextrin.
    Type: Application
    Filed: December 21, 2015
    Publication date: November 17, 2016
    Inventors: J. Jeffry Howbert, Muralikrishna Duvvuri, Robert Hershberg, Gregory Dietsch
  • Substituted Benzoazepines as Toll-Like Receptor Modulators
    Publication number: 20160129010
    Abstract: Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-versus-host disease.
    Type: Application
    Filed: August 4, 2015
    Publication date: May 12, 2016
    Inventors: James Jeffry Howbert, Gregory Dietsch, Robert Hershberg, Laurence E. Burgess, Joseph P. Lyssikatos, Brad Newhouse, Hong-Woon Yang
  • Substituted benzoazepines as toll-like receptor modulators
    Patent number: 9242964
    Abstract: Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: January 26, 2016
    Assignees: VENTIRX PHARMACEUTICALS, INC., ARRAY BIOPHARMA, INC.
    Inventors: James Jeffry Howbert, Gregory Dietsch, Robert M. Hershberg, Laurence E. Burgess, George A. Doherty, C. Todd Eary, Robert D. Groneberg, Zachary Jones
  • Toll-like receptor agonist formulations and their use
    Patent number: 9216192
    Abstract: The present invention is directed generally to stable formulations of a TLR agonist preferably a TLR7 or a TLR8 agonist, for use in the treatment of cancer, preferably solid tumors and lymphomas. Specifically, the present invention is directed to stable formulations of up to 50 mg/ml of a TLR agonist which comprise a cyclodextrin.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: December 22, 2015
    Assignee: VentiRx Pharmaceuticals, Inc.
    Inventors: J. Jeffry Howbert, Muralikrishna Duvvuri, Robert Hershberg, Gregory Dietsch